Vacation rentals in Puxico

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Top-rated vacation rentals in Puxico

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite

A rustic cabin is shown with a wooden facade and a stone chimney, surrounded by lush greenery. An American flag is displayed on a porch, which features hanging flower baskets and a welcoming atmosphere. Sunlight filters through the trees, casting dappled shadows on the lawn.

Cabin in Dexter

4.96 out of 5 average rating, 81 reviews

Cozy cabin on the hill! Free Wifi!

Minutes away from fishing hunting and shopping! Located next to a family farm. You can arrange a time to visit and meet their cute cuddly critters! Be our guest! Looking forward to a ideal country cabin or relax in the beautifully lit claw foot tub or roast some delicious marshmallows next to the large rock fireplace located in the living room. It is amazing but the sleeping quarters are located up a flight of stairs if you have any disabilities that prevent stairs the cabin is not ideal.

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Top guest favorite

The exterior of a charming house is depicted, featuring a light-colored facade with a inviting front porch. Lush greenery and flowering plants surround the entrance, and a well-maintained lawn adds to the welcoming appearance. The roof is finished in metal, enhancing the home's rustic appeal.

Home in Puxico

5 out of 5 average rating, 24 reviews

The Sunday House | Sleeps 11

Welcome to our charming Puxico house, designed for comfort and connection! Enjoy an upscale kitchen with a butler’s pantry, a spacious dining room with a custom table, and a cozy sunroom for relaxing. Bedrooms feature premium bedding with extra blankets and pillows, plus a laundry room with a vintage utility sink. The large fenced backyard is perfect for games and outdoor dining. Walk to the town center or explore nearby Mingo National Wildlife Refuge, Wappapello Lake, and more. Book today!

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Top guest favorite

Treehouse in Greenville

5 out of 5 average rating, 378 reviews

Treehouse Escape• Secluded•Hot Tub year around

"The Roost" is a modern treehouse 2 hrs south of St Louis near Wappapello Lake. Yes it has indoor plumbing & running water. Accommodates two adults, has a fully equipped kitchen, and breakfast items are provided for you to cook. Surrounded by thousands of acres of national forest. Observe wildlife sightings from the deck while soaking in the private hot tub, sleep comfortably in a queen size pillowtop Serta bed on a Motion Air base, and relax as you enjoy the ambience of the fireplace.

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Top guest favorite

Cabin in Williamsville

4.97 out of 5 average rating, 118 reviews

Cypress Bend cabin w/hot tub on Black River

Cozy new built cabin on a bend of the beautiful Black River. You’ll walk up the 14 stairs to a large screened in covered deck with hot tub and sitting area, and gas grill. The glass doors and windows allow you views of the river. The theme throughout is Indian-Aztec. Accommodates only two adults. If you’re looking for a peaceful/romantic get away this is the perfect place. Located approximately 2 hours south of St. Louis, and less than 15 minutes from Poplar Bluff, MO.

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Guest favorite

The cabin exterior showcases a unique combination of stone and siding with a gently sloped roof. A small wooden deck leads to the front door, while a gravel driveway offers ample parking space. Surrounding trees provide a natural backdrop.

Cottage in Wappapello

4.92 out of 5 average rating, 62 reviews

Ridge Road Casita

Welcome to Ridge Road Casita near beautiful Wappapello Lake. Take time to unwind and enjoy the lake life and all it has to offer in our one bedroom, quaint and cozy cabin. Within minutes from Peoples Creek and Sundowner Marina. We have plenty of space to park a boat and vehicle. The Camp is approximately 8 miles away, if you’re in the area to catch a live band. There is a Dollar General close by and a variety of restaurants within the Wappapello area to enjoy!

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Guest favorite

A charming cabin sits amid lush greenery, featuring a welcoming front porch with seating. The quaint exterior is complemented by muted earth tones, and colorful elements enhance its character. The sky transitions from blue to soft pink at sunset, adding a serene backdrop.

Cabin in Williamsville

4.87 out of 5 average rating, 127 reviews

Keener Springs Springhouse

The Spring House at Keener Spring sits on a bluff overlooking beautiful Black River in the Ozark Foothills. Keener Spring is one of the largest privately owned springs in the country emitting 14 million gallons per day. The spring and the unique, water filled Keener Cave are the focal points of the 65 acre property. There are numerous places including our gravel bar within walking distance to BBQ, picnic, or just relax in the sunshine with your favorite beverage.

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Guest favorite

A cabin with a red metal roof is framed by lush greenery and a gravel driveway. The stone chimney adds texture to the facade, while potted plants line the entrance, creating an inviting approach.

Cabin in Wappapello

4.94 out of 5 average rating, 190 reviews

Crooked Paddle

Welcome to the Crooked Paddle at Wappapello, MO. This vacation getaway is located just minutes away from Peoples Creek and Sundowner Marina Boat Launches, if you desire fishing or watersports. If hunting is your desired use, this getaway is close to Duck Creek Conservation Area, Otter Slough Conservation Area, and Mingo National Wildlife Refuge Visitor Center. Whether you want a couples retreat, hunting lodge, or family getaway this cabin will meet your needs.

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Superhost

A cozy cabin is set amidst natural surroundings, showcasing a hot tub on a wooden deck. A gravel pathway leads to the entrance, lined with soft lighting and surrounded by trees, enhancing the secluded ambiance of the private property near the lake.

Home in Lost Creek Township

4.84 out of 5 average rating, 129 reviews

Camp Bluegill Lake House

New, modern, and cozy with tons of amenities and activities. Relax in the hot tub overlooking the private lake or lounge on the private beach and watch the kids have fun in the paddle boat. Beautiful, secluded property on 5 acres. Tons of parking and easy in and out access for trailers and covered parking. Minutes from beaches, boat ramps and marinas on beautiful Lake Wappapello. Multiple state parks, trails and recreational activities also within minutes.

LocationFamilySleep quality

Superhost

The living area features a cozy couch set against a textured wall, with a vibrant area rug adding color to the space. A kitchenette is visible in the background, equipped with essential appliances, while a ladder leads to an elevated sleeping area. Natural light enhances the overall atmosphere.

Tiny home in Wappapello

4.69 out of 5 average rating, 16 reviews

Tiny Home Heaven at Wappapello Lake - Sleeps 5

This tiny home is the perfect spot to enjoy your stay at Wappapello Lake. This vacation has plenty of parking to accommodate your vehicles, trailer, and boat. We are conveniently minutes away from a Dollar General, Peoples Creek and Redman Creek recreation areas, and Sundowner Marina. This tiny home retreat will suit your needs if you are looking to fish, hunt, hike/bike trails, enjoy the beach, or just relax with your favorite people.

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Top guest favorite

A charming house is presented with a dark exterior and a peaked roof. Steps lead to the entrance, flanked by two large windows that allow natural light to fill the interior. Lush green grass surrounds the property, providing a welcoming atmosphere.

Home in Advance

4.98 out of 5 average rating, 42 reviews

2 King,2 Twin,1 Futon House

Bring the whole family to this great place with lots of room for fun. This gorgeous house offers two king beds and two twin beds. House features AC, iron, coin, laundry, Wi-Fi, heating, hairdryer, games,fully stocked kitchen. Plus a cozy living room with the futon for additional space. Kick back and relax and enjoy everything Advance and our house has to offer. The house sits just minutes away from prime duck hunting area..

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Guest favorite

The exterior of a rustic cabin is presented, featuring a gravel pathway leading to a covered porch equipped with a table and umbrella. Two white chairs are positioned beside the entrance. A fire pit stands nearby, surrounded by a landscaped area with trees.

Cabin in Wappapello

4.82 out of 5 average rating, 62 reviews

Private park setting for cabin on Rockwood point.

Cabin in a secluded area perfect for those looking for a lake get away without the hassle of other campers or busy streets right next to your site. Located near boat landings, marina, beaches, restaurants and grocery store. Enjoy easy access to the water and hiking trails. Cabin has AC and heat, making it great for any season (Lake/dam view in the winter). Come and enjoy the lake!

FamilyLocationOutdoor spaces

Top guest favorite

A modern cabin sits perched on a hillside, featuring a striking A-frame design. Large windows dominate the front façade, offering glimpses of the interior. The expansive porch is fitted with railing, surrounded by lush greenery, creating a serene and inviting outdoor space.

Cabin in Williamsville

4.99 out of 5 average rating, 71 reviews

Honky Tonk Hideout

“Hello darlin’,” welcome to the Honky Tonk Hideout in Poplar Bluff, MO (about 2.5-3 hours south of St. Louis, MO). Whether you are looking for a place to wash away those “9 to 5” blues, looking for some “wide open spaces,” or wanting to meet up with some “friends in low places,” Honky Tonk Hideout invites you to stay.

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