
House vacation rentals in Punta Santiago, Humacao, Puerto Rico
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Top-rated house rentals in Punta Santiago, Humacao, Puerto Rico
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Punta Santiago, Humacao, Puerto Rico house rentals
House rentals with a pool

Beautiful Getaway Home | Private Pool | 4BD

Renald's Place

Surf Side, Private Salt Water Pool, Ocean View

Between sea and mountain El Yunque

❤️PRIVATE POOL,Beach home,BioBay Tour walk distance

Casa Amor Home Esperanza Salt Pool- close to Beach

Fabulous Ocean Views /Private Infinity Pool /4 BR

Casa Blanca - Enchanting rainforest stay with pool
Weekly house rentals

Your spacious 5-bedroom Beach Villa awaits!

Rare To Find Warm House

Marcelino's Little House

Flecha’s beach house in Punta Santiago

Mares Tropical house near el Malecon

Walk to the BEACH Ocean Breeze

Evy's House! Perfect Getaway

Davide, Colinas del Yunque *Paraiso Escondido* NEW
Private house rentals

Casa Serena Country Villa, Cidra, Puerto Rico

Relax Home

Private 2BR/2.5 BA W. Ocean View & Heated Infinity Pool

Tropical Naguabo Beach House | Pool & Beach

Nature Lover's Escape 3200acre Sanctuary & beach.

Stone House PR romantic and modern

Relaxing, three bedroom home with private pool

Respir@ Villa Activities
Quick stats about house rentals in Punta Santiago, Humacao, Puerto Rico
Total rentals
50 properties
Nightly prices starting at
R882 ZAR before taxes and fees
Total number of reviews
2.6K reviews
Family-friendly rentals
40 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with a pool
20 properties have a pool
Destinations to explore
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- Rentals with lake access Punta Santiago, Humacao, Puerto Rico
- Rentals with beach access Punta Santiago, Humacao, Puerto Rico
- Rentals with pools Punta Santiago, Humacao, Puerto Rico
- Rentals with outdoor seating Punta Santiago, Humacao, Puerto Rico
- Rentals with a patio Punta Santiago, Humacao, Puerto Rico
- Pet-friendly rentals Punta Santiago, Humacao, Puerto Rico
- Beachfront rentals Punta Santiago, Humacao, Puerto Rico
- Waterfront rentals Punta Santiago, Humacao, Puerto Rico
- Rentals with a washer and dryer Punta Santiago, Humacao, Puerto Rico
- Family-friendly rentals Punta Santiago, Humacao, Puerto Rico
- House rentals Humacao Region
- House rentals Puerto Rico
- Flamenco Beach
- Mosquito Bay Beach
- Playa del Dorado
- Praia de Luquillo
- Liquillo Beach
- Playa de Vega
- Distrito T-Mobile
- Playa Puerto Nuevo
- Playa Sun Bay
- The Saint Regis Bahia Golf Course
- Rio Mar Village
- Playa el Convento
- Toro Verde Adventure Park
- Coco Beach Golf Club
- Playa Maunabo
- Playa Puerto Real
- Beach Planes
- Playa de Cerro Gordo
- Punta Bandera Luquillo PR
- Balneario Condado
- Carabali Rainforest Park
- Playa Puerto Nuevo
- Cerro Gordo National Park
- Punta Guilarte Beach