Private suite vacation rentals in Pickens County

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Top-rated private suite rentals in Pickens County

Guests agree: these private suite rentals are highly rated for location, cleanliness, and more.

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Top guest favorite
A cozy living area is presented, featuring a large sectional couch and two recliner chairs. A sizable wall-mounted TV is visible, along with a bookshelf filled with games and movies. Soft lighting from a nearby lamp highlights the inviting atmosphere.
Guest suite in Pickens
5 out of 5 average rating, 11 reviews

Pickens Retreat

Located 1/2 mile from downtown Pickens, 1 mile from Hagood Mill, 20 mins from table rock and 30 mins from Clemson, there's a little bit of everything within reach. Private entrance, gas fireplace, full bathroom, 75” Roku TV, all amenities except stove (air fryer and microwave are available). This is the entire first level of a two story home. We live on the 2nd level and have our own separate entrance. Dogs 25lbs or less unless hypoallergenic. No cats. Fridays check-in will allow 2 day minimum

Guest favorite
A large blue swimming pool is framed by a secure black fence, with a water slide on one side. A pair of lounge chairs is positioned for relaxation, and trees provide a natural backdrop. A covered deck area is visible in the background.
Guest suite in Easley
5 out of 5 average rating, 20 reviews

Private, Spacious Guest Apartment- Pool Hot Tub

This is for a 1650 sq ft private, basement apartment, not whole house, with every amenity a full home normally offers and more! ★ Private Entrance ★ Swimming Pool w/ Slide, Basketball ★ Hot tub ★ Fire Pit ★ Air Hockey, Pool, and Ping Ping ★ Kids Corner with Reading nook, Toys, Games, and Books ★ Badminton, Volleyball, Cornhole, Ladder ball ★ Gas grill ★ Netflix, Amazon Prime, Hulu, ESPN +, Disney + on 70” and 65” TVs ★ Covered Patio with Comfy Furniture ★ Fully Stocked Kitchen ★ Washer/Dryer

Guest favorite
A spacious living area is highlighted by a billiard table in the foreground, with a comfortable seating arrangement visible. The open kitchen is seen in the background, showcasing modern appliances, light wood accents, and a dining area. Natural light illuminates the inviting space.
Guest suite in Central
4.95 out of 5 average rating, 126 reviews

Spectacular 3 brm/2 bath Terrace Escape-Clemson

A perfect place to spread out & enjoy a forest retreat. This is a 1500 sq/ft, a newly furnished terrace level of our home that can accommodate 6+ with a Murphy bed in third bedroom. It has a full kitchen ready to cook a big meal and washer/dryer and pool table SmartTV with Roku that can connect to all your favorite online channels as well as SlingTV for sports or other popular channels, Hi-Definition antennae for local stations. Pets are not allowed as some of our guests have allergies.

Top guest favorite
The exterior of the home features a brick facade with brown shutters framing a large window. Lush greenery and flowering plants are visible in the foreground, enhancing the appeal of the property. A sloped roof and a dormer window are seen above, adding character to the design.
Guest suite in Easley
5 out of 5 average rating, 17 reviews

Sweet Saluda Suite

Traveling Professionals - this is the perfect location! Near local hospitals, so traveling nurses can get to work quickly and return to a quiet retreat! 8 miles from downtown Greenville, this apartment suite is the perfect, tranquil space. Located on a tree lined street in a quiet neighborhood, this is an ideal spot to call home! Close to the Swamp Rabbit Trail, Furman University, Saluda Lake, as well as a short drive to Clemson University, anything and everything you need is close by!

Superhost
A sturdy wooden staircase leads up to a private entrance, framed by an attractive wooden exterior. Softly glowing string lights outline the steps, enhancing the welcoming ambiance. A small seating area is visible at the top, surrounded by lush greenery and flower beds.
Guest suite in Greenville
4.88 out of 5 average rating, 375 reviews

Lakefront modern private guest suite 6mi to DT

MINI PRIVATE OASIS. 6 MILES TO DOWNTOWN GREENVILLE! LAKEFRONT + PRIVATE DOCK NY Times #1 AMERICAN CITY! Experience modern luxury in your serene mini suite. Please note: the suite is located as an extension attached to a classical Scandinavian chalet. The suite is private. No shared spaces, shared soundproofed wall. 6mi downtown Greenville Amenities include: - Private entrance & patio - Private dock - 43” Roku TV - Charcoal grill, fire pit - Luxury toiletries - Blackout curtains

Top guest favorite
A bright living area is showcased with large windows offering views of the surrounding trees. Comfortable seating includes two sofas and an armchair, arranged around a coffee table. A patterned area rug adds warmth, while a TV is mounted on the wall.
Guest suite in Six Mile
4.94 out of 5 average rating, 88 reviews

Charming Clemson Cottage on Lake Keowee

Activities such as fishing, swimming, boating, and kayaking can be enjoyed right from the property. Enjoy the serenity of the lake while taking in the beautiful views of the surrounding nature. The cottage is perfect for a romantic getaway, Clemson football games or a gathering of friends. The fully equipped kitchen allows for easy meal preparation and the outdoor grill is perfect for cookouts. After a day of outdoor activities, relax on the patio and take in the sunset over the lake.

Top guest favorite
The property is shown from the lake, highlighting a spacious home surrounded by trees. A gentle lawn leads to a private dock along the water's edge, reflecting the tranquil surroundings. Scenic views of nature complement the architecture and landscape.
Guest suite in Greenville
5 out of 5 average rating, 175 reviews

Cozy, Cute & Clean Cottage on Saluda Lake

Stunning lake views from private covered deck with daily western sunsets. Large dock to sit, sun, read or fish. Two kayaks with life vests available to tour the water. Saluda Lake is said to be one of Greenville's best kept secrets. Though a small 331 acre lake, the nearly 2 mile river to the 1920's working dam is great water to boat and fish. 13 mins to main street Greenville; 5 mins to Furman University; 45 mins to Clemson University or Lake Hartwell area. 5 mins to grocery stores.

Top guest favorite
Two individuals sit on a dock overlooking the calm lake, draped in colorful beach towels. Adirondack chairs provide comfortable seating, positioned to enjoy the serene water views and surrounding greenery. A potted plant adds a touch of color to the peaceful scene.
Guest suite in Seneca
4.96 out of 5 average rating, 122 reviews

Hartwell Escape 6 mi to Clemson Beautiful views

We recently purchased this gorgeous home on Lake Hartwell, in a secluded cul-de-sac in a quiet neighborhood (6 miles to Clemson..ALL BACKROADS) You will have the entire bottom floor with separate entrance . Enjoy beautiful lake views on the covered porch or from our dock. A Private Neighborhood Boat ramp is 25 feet from our home. Bring your boat, use our dock, space for multiple trailers. Driveway parking. Dogs Welcome! ($25 pet fee/entire stay)

Top guest favorite
A spacious bedroom features a large bed with a patterned bedding set, complemented by a wooden headboard. Natural light filters through large windows, framed by shutters. A comfortable couch and wooden furniture create a cozy seating area, with decor items arranged tastefully around the room.
Guest suite in Clemson
5 out of 5 average rating, 29 reviews

Downtown Clemson - Private Guest Studio Suite

Take a break and unwind at this peaceful oasis nestled in a quiet, and beautiful downtown neighborhood. The location offers easy access to all Clemson has to offer while providing a quiet and pleasant stay in a lovely area. This private studio is connected to the main house but you will not share the space with others - it will be all yours. You have your own entrance and small private courtyard/patio to enjoy the weather outside. .

Top guest favorite
A spacious living area features a brown leather sofa and a light blue rocking chair, complemented by a round coffee table. A dining table with four chairs is visible, along with a streamlined kitchen area that includes a refrigerator and stove. Natural light fills the space.
Guest suite in Seneca
4.95 out of 5 average rating, 93 reviews

Forest Hills Hideaway

A little piece of home offering far more space and privacy than your typical hotel room. Our goal is to provide you with a quiet, comfortable, and serene space while you visit the area from near or far. From Forest Hills Hideaway you are: * 4.5 miles to Death Valley * an easy drive to hikes, waterfalls, lake destinations, the mountains, and more. Our mission: Hebrews 13:1-2 "Let brotherly love continue..."

Top guest favorite
A spacious living area features a large sectional sofa adorned with soft pillows, elegantly positioned on a patterned area rug. Natural light fills the space through multiple windows, complementing the neutral-colored walls. A coffee table with a decorative centerpiece is placed in front of the couch.
Guest suite in Easley
4.95 out of 5 average rating, 198 reviews

Lakefront Oasis | Kayaks & SUP | Near Greenville

Escape to this cozy lakefront oasis just 15 minutes from Greenville. Enjoy a luxury experience with stunning views, peaceful vibes, and room for six. Kayaks and paddle boards await for water adventures, plus a spacious fire pit for evening relaxation. Whether you’re seeking tranquility or city fun, this beautifully appointed retreat offers the perfect blend of both. Book your lake life getaway today!

Top guest favorite
The spacious outdoor patio features comfortable seating arranged in an L-shape, complemented by a dining table. An outdoor kitchen is visible in the background, enhancing the functionality of the space. Lush greenery surrounds the area, contributing to a serene environment.
Guest suite in Clemson
5 out of 5 average rating, 79 reviews

The Tiger Den - 1/2 mile from Clemson University

Welcome to our charming, newly-renovated guest suite! This cozy 2-bed, 1-bath oasis sits in a family-focused, quiet neighborhood, just over a half mile from Clemson University. Enjoy the exclusivity of our patio and outdoor kitchen for memorable gatherings. Book now for an unforgettable stay!

Popular amenities for Pickens County private suite rentals