House vacation rentals in Pickens County

4.94 out of 5 average rating, 101 reviews

A lush green lawn extends across the image, framed by trees and a backdrop of rolling hills. A bright blue sky dotted with fluffy white clouds adds to the serene atmosphere. The spacious landscape offers a tranquil view of the surrounding nature.

Home in Liberty

3 Bed Home Overlooking Fishing Pond on 10 Acres

This Home is a retreat in of itself! All New Accommodations offer Large eat in Kitchen, Primary Suite with Primary Bath. Stocked Fishing Pond! Peaceful and relaxing property to enjoy privately. If you are a foodie or shopper Greenville is only 15 miles away. Greenville has landed on countless "best of" lists so it's a must see! If Clemson is what you love we are twenty minutes from campus! Business class wifi too and cable TV Enjoy Great hiking at one of the close state parks too

A newly constructed duplex is depicted, featuring a light grey exterior with black shutters. The entrance is framed by two elegant chairs on the porch. A spacious driveway leads to a well-maintained area, surrounded by neat landscaping and a clear blue sky.

4.95 out of 5 average rating, 129 reviews

Cottage in Pickens

Enjoy easy access to all the Upstate has to offer! This newly constructed 2 bedroom, 1 bath duplex apartment is located along the Doodle Trail bike route. Enjoy hiking trails and waterfalls at Table Rock and Caesars Head State Parks, catch a Clemson football game, or check out Falls Park and downtown Greenville, all from one convenient location! The home is across the street from a well-maintained local park and playground and within walking distance to a coffee shop and restaurants.

4.91 out of 5 average rating, 182 reviews

A single-story home is presented with a light-colored facade and a covered front porch. The driveway leads to a garage, and neatly trimmed bushes frame the entrance. Tall trees and greenery provide a natural backdrop, enhancing the property's privacy and peaceful setting.

Home in Pendleton

Comfort & Convenience Close to Campus

The perfect blend of modern charm and full comfort & convenience just minutes from Clemson, The Pendleton Square and HWY access. You will be sure to have everything you need for your visit. Comfortably sized bedrooms with queen size beds. Spacious living area with cable TV & Netflix. Bright and open kitchen and dining fully equipped for all your cooking needs. Whether you're traveling alone for a little peace & quiet, with friends, or with family... we hope you enjoy your time here!

4.99 out of 5 average rating, 210 reviews

A charming home is presented in a serene neighborhood setting, featuring a well-maintained lawn and flowering shrubs. The exterior showcases a light-colored façade with a welcoming front porch and a spacious driveway leading to a two-car garage.

Home in Seneca

The Cozy Cottage

Beautiful, well-maintained home located in a private subdivision just minutes away from shopping, restaurants, lakes, golf courses, and Clemson University. This home has a fully equipped kitchen for dining in and a back patio for grilling out. The backyard overlooks a peaceful wooded area, providing a serene and private escape. Our home offers the perfect blend of tranquility and convenience. Perfect for getaways, football weekends, graduation, and other Clemson University events!

5 out of 5 average rating, 114 reviews

A modern one-story ranch house is depicted in a tranquil setting, featuring a spacious driveway and manicured landscaping. Natural light illuminates the exterior, enhanced by a welcoming entryway with decorative planters and a covered porch, surrounded by lush greenery and large trees.

Home in Travelers Rest

Modern Wooded Retreat

Modern, 1.6 acre retreat. Relax in fun + style & seclusion! Dog friendly, fully fenced back yard! Located 5 min. To downtown TR and 20 min to downtown Greenville! Roast marshmallows by the firepit, play giant jenga and connect 4, and take in the Carolina sunset. Minutes to the swamp rabbit trail and centrally located to lakes, hiking and exciting nightlife. Let us host you, while you explore everything Greenville and Travelers Rest have to offer, with all the comforts of home.

A spacious porch offers panoramic mountain views through large glass panels, framed by soft white curtains. The wooden floor extends outdoors, inviting relaxation amidst the surrounding greenery and distant mountain ranges.

4.96 out of 5 average rating, 181 reviews

“Mountain View Paradise” Waterfall Oasis

The peaceful sounds of a Rushing Waterfall welcome you to “Mountain Paradise”. Surrounded by 500 acres of forest and waterfalls, you have the ultimate level of privacy. Exquisitely furnished oasis with 3 bedrooms and 3 Full Baths. Enjoy 2 Master Suites with their own en suite Master Baths. Enjoy a game of golf at The Rock Golf Resort. Lake Keowee and Lake Jocassee are just minutes away. Visit Greenville, SC or head up to Brevard, NC both just 45 minutes away.

An aerial view showcases a serene landscape featuring a four-acre pond surrounded by lush greenery and autumn foliage. A winding driveway leads to a guest house nestled within the wooded area. Rolling hills provide a backdrop, enhancing the natural beauty of the property.

4.97 out of 5 average rating, 150 reviews

Our Slice of Heaven w/Views of Table Rock-Pickens

Our slice of heaven is located in the foothills of the Blue Ridge Mountains only 8 mins from Table Rock State Park. Our guest house is sitting on 55 wooded acres with our 4-acre pond and amazing awe-inspiring panoramic views of Pinnacle and Table Rock Mountain. Wrap yourself in the serenity of nature, with nothing more to wake you in the morning than the pleasant sounds of songbirds beckoning you to delight in the new day.

4.92 out of 5 average rating, 193 reviews

A welcoming cabin is nestled among tall trees, softly illuminated by string lights against the evening sky. A pathway leads toward the water, inviting relaxation with the gentle ambiance of nature surrounding the space.

Home in Easley

Spectacular Lakefront Retreat on the Saluda

Stunning views, quiet, still waters, wildlife in its natural habitat. This and more is what you'll find at Lakepoint on the Saluda. Better yet, this property is located on the water with 460' of lakefront and is just minutes from downtown Greenville, Furman, and Paris Mountain. Within 35 minutes you can be in Clemson. Includes kayaks, a canoe, hot tub (SEASONAL), work out room, and some of the best fishing in the upstate!

A cozy living area features a patterned area rug and a colorful loveseat, complemented by a comfortable chair. Light from a nearby lamp casts a warm glow. A small dining area with a wooden table is visible in the background, and a kitchenette is accessible beyond.

4.97 out of 5 average rating, 155 reviews

Hidden Retreat

4 private acres just off Hwy 11. HIKE - connector to the Palmetto trail and Table Rock State Park. BIKE - popular biking routes; Hwy 11, Hwy 288 and Hwy 178 + Doodle & Swamp Rabbit Trail. GOLF - 1 course 5 minutes away several others nearby. WATERFALLS - including the highest in the east. MOUNTAIN LAKES - 2 of the best, Jocassee & Keowee. HIDDEN RETREAT - close to many outdoor adventures. Up to 6 guests.

4.88 out of 5 average rating, 148 reviews

A living area is presented with a brown leather sofa and a white coffee table atop a textured rug. Light is provided by a ceiling fan and window, accompanied by framed artwork on the walls. A wall-mounted television is visible opposite the seating arrangement.

Home in Easley

Livin' Easley-walk to downtown-close to everything

Welcome to Livin' Easley! Your family will be close to everything when you stay at this newly renovated bungalow style house. Downtown Easley shops, restaurants, bars and The Silos are within walking distance, and Greenville and Clemson are just a short drive away. If you'd rather stay in, enjoy everything the house has to offer including bumper pool, a card table, board games, horseshoe pits, and Netflix.

4.96 out of 5 average rating, 273 reviews

A single-story guest house is set within a spacious green lawn, bordered by mature trees. The front porch features a white railing and steps leading to the entrance. The exterior is clad in light-colored siding, complemented by white shutters on the windows.

Home in Central

The Little House @ Cozy Hollow

Country living close to town. 2 miles from Cateechee Beach Park, 4 miles from SWU, 10 miles from Clemson, 12 miles from Oconee Nuclear Station, 13 miles from Garrison Arena, and 25 miles from Greenville. Enjoy your getaway at this private guest house with private drive, front & back porches, tv (streaming via Hulu Live, Disney+, Netflix, and more), washer/dryer, and full kichen including Keurig.