House vacation rentals in Panama Canal

Find and book unique houses on Airbnb

Top-rated house rentals in Panama Canal

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Superhost

A clear view of a tranquil swimming pool is framed by wooden beams, showcasing reflections of surrounding greenery. Lush tropical plants create a serene backdrop, enhancing the connection to nature.

Home in Gamboa

4.88 out of 5 average rating, 97 reviews

BirdHouse@ Gamboa Panamá Canal

Explore the wonders of the Panama rainforest and return to our magical tropical home! This unique house and pool is a wonderful place to escape the hustle of Panama City, celebrate nature, and enjoy family and friends. Gamboa is a safe, quiet town embedded in the Soberania National Park; it is the entry point to Pipeline Road, some of the best birding in the world. Or take leave of the forest and watch manatee, while fishing for peacock bass in Gatun Lake or paddling kayaks up the Chagres River.

Top guest favorite

A stone pathway leads through lush tropical foliage toward a welcoming entrance. Tall trees and vibrant greenery frame the path, creating a serene approach to the property, which is partially visible in the background, surrounded by nature's tranquility.

Home in Panama City

5 out of 5 average rating, 46 reviews

Mountain Retreat

Relax and unwind at this peaceful property nestled on two hectares of lush tropical vegetation surrounded by the sights & sounds of nature. Located at Panama's Blue Mountain(Cerro Azul), 30 kilometres from Panama City. This cozy & comfortable home is equipped with modern amenities & chic decorative touches. It consists of a main house with 2 bedrooms & a 2 bedroom cottage. It has a spacious terrace, pool & jacuzzi overlooking Panama City. The property also boasts its own spring water well

Top guest favorite

An outdoor space features a heated pool surrounded by light-colored tiles. A covered patio includes modern seating arrangements and a table, suitable for dining. Lush greenery is visible beyond the walls, with a glimpse of the sky above, providing a bright and open feel to the area.

Home in Vacamonte

5 out of 5 average rating, 24 reviews

The Hidden Gem

Here you will find your home away from home in this hidden gem. Furnished with all of the creature comforts, you will have plenty to do from relaxing on the patio while listening to music, to taking a dip in the heated pool, to relaxing on the comfy couch and watching Netflix. The house is situated on a beautiful gated beach property where you can find various activities from kayaking to the local water park. You can find the relaxation you were searching for here in this hidden gem.

Top guest favorite

The exterior of a modern house is shown, featuring a covered entrance and a driveway with a parked car. Lush green grass and tropical plants add a touch of greenery, complemented by a palm tree. Large windows offer light to the interior spaces.

Home in Panamá

4.92 out of 5 average rating, 12 reviews

Excellent and affordable house in La Chorrera.

The house is completely private, has parking at the entrance, the master bedroom has a double bed, air conditioning and 65” smart TV and a fully private bathroom, a secondary bedroom with a double bed, air conditioning and 43” smart TV, a secondary bedroom with a twin bed, fan and 32” smart TV, and a shared bathroom. The living-dining room has a sofa, coffee table, TV table with a 32” smart TV, a 4-seat dining room, and a fully-equipped kitchen with a 16-foot refrigerator.

Guest favorite

A tranquil dipping pool is framed by lush greenery, featuring white loungers and a large umbrella for shade. The pool area exudes a serene vibe with vibrant bougainvillea in the background, enhancing the inviting outdoor space.

Home in Taboga Island

4.95 out of 5 average rating, 197 reviews

Casa Rosie - Dream Home on Tabogá Island

Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Guest favorite

A lush green lawn showcases well-maintained grass, framed by tropical plants with vibrant yellow leaves. In the background, a spacious outdoor area is visible, featuring a covered seating area. Hammocks are gently swaying, inviting relaxation amidst the natural surroundings.

Home in Panamá

4.87 out of 5 average rating, 38 reviews

Wonderful nature

Enjoy a family retreat in the heart of nature, where tranquility envelops you. This cozy accommodation, surrounded by a beautiful garden in the Metropolitan Natural Park, offers you a unique escape just 3 minutes from Albrook Mall and 5 minutes from downtown. Wake up to birdsong and a visit from the ñeques (agoutis), while relaxing in an exclusive and lively atmosphere. The perfect getaway to disconnect and enjoy nature with all the amenities!

Top guest favorite

A spacious living and dining area is depicted, featuring a blue sectional sofa with yellow accent pillows. A glass dining table with yellow placemats and black chairs is shown. Natural light enters through windows, revealing a glimpse of greenery outside.

Home in Panama City

4.8 out of 5 average rating, 107 reviews

Spacious Panama House in the 'heart of the city'

You couldn't ask for a better place to stay while you visit Panama. This location is perfect, while other properties might advertise similar amenities; not one of them can boast a combination of space and amazing location quite like this one. This is very private & secure property in a fantastic, & very safe area right in the heart of the city & close to everything! An oasis in the middle of the city with AC IN EVERY ROOM AND DININING ROOM.

Top guest favorite

A private pool area is framed by lush tropical plants and trees, with lounge chairs situated nearby. The pool’s clear blue water reflects the surrounding greenery and the structure in the background, which includes a covered patio for relaxation.

Home in Las Colinas de Caceres de Arraijan

4.98 out of 5 average rating, 215 reviews

Tropical Haven with Yoga Platform

Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

Guest favorite

A private rooftop terrace offers expansive views of the ocean and skyline. Comfortable seating arrangements include a coffee table and lounge chairs beneath a shaded umbrella. Decorative plants enhance the outdoor space, while string lights provide a warm ambiance during evenings.

Home in Panamá

4.93 out of 5 average rating, 124 reviews

Exceptional three-story building with sea view

This stunning three-story property, located in Casco Viejo, boasts a terrace with a sea view. Designed with a focus on elegance and relaxation, the house features spacious and well-lit interiors adorned with modern and high-quality decor. The strategic location of the house allows for breathtaking views from the terrace, offering a unique blend of luxury and relaxation in a historic and picturesque setting.

Guest favorite

The kitchen area features a black dining table with four chairs, complementing a modern microwave and refrigerator. Warm decorative elements, including wall art and a candle, add character to the space, which is equipped with essential appliances and a clean countertop.

Home in Panamá

4.93 out of 5 average rating, 370 reviews

Private Studio 10 Min from the Airport!

Entire apartment 10 minutes from the airport! The apartment is fully furnished including appliances and kitchen items, toiletries, dining room, work table and more. Just a few minutes walk from the SAN ANTONIO METRO Station, restaurants, shopping malls, laundries, supermarkets and pharmacies. We offer tours to San Blas to make the most of your trip. Our house is your house in Panama 🇵🇦

Guest favorite

The interior showcases a cozy seating area with a brown sofa and two clear chairs around a glass table. A spacious bed with warm bedding is positioned against the wall. Natural light enters through large windows adorned with soft curtains, highlighting decorative shelves and artwork.

Home in Panamá

4.92 out of 5 average rating, 153 reviews

Golden Space | By Paradox

PRIVATE APARTMENT IN PANAMA CITY, CLOSE TO CASCO VIEJO. If you're looking to get submerged into real Panama and live among the real locals. This is the right place to be. For More Info or visual content, follow us on IG as Paradox Experience and visit our Virtual Showcase with the link in our IG BIO. More than a regular stay, we are an experience.

Superhost

A private terrace features lounge chairs and green outdoor carpeting, providing a comfortable space for relaxation. A small pool with blue tiles is visible, with scenic ocean views and a distant island in the background, creating a serene setting.

Home in Taboga

5 out of 5 average rating, 5 reviews

Oceanview loft with large private terrace

Escape to this stylish oceanview loft featuring a spacious private terrace perfect for morning coffee or sunset drinks. Located just steps from the beach, this modern space offers a fully equipped kitchen, open living area, and stunning views of the sea. Ideal for couples or solo travelers seeking comfort and privacy.