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Hotel vacation rentals in Panama Canal

Find and book unique hotel rentals on Airbnb

Top-rated hotel rentals in Panama Canal

Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.

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A vibrant terrace features colorful umbrellas shading lounge chairs around a refreshing plunge pool. Lush greenery surrounds the area, complementing the bright yellow walls of the two-story building in the background, which overlooks the scenic landscape.

Hotel room in Taboga

4.9 out of 5 average rating, 10 reviews

Eco Lodge Mango Room Plus New

You’ll be charmed by this special room for two. This ground floor room with two ocean and garden view windows offers a pillow top double Bed/Full (137cm x 190cm), 2 bedside lights, free WiFi, a flat-screen smart TV, and a private ensuite bathroom with a shower. Enjoy the shared balcony with ocean, tropical garden or forest view and to a shared hammock area. Additionally enjoy: Plunge Pool -Sun Terrace - Gardens - Nearby ancient forest. Pets in suites only, not this room. Room is air conditioned.

A spacious room features a king bed with soft white linens and colorful striped accent pillows. The headboard is constructed from light wood, complementing the contemporary design. A view of the city skyline is visible in the artwork above the bed, enhancing the room's ambiance.

Hotel room in Panamá

4.9 out of 5 average rating, 10 reviews

Very Nice Downtown Panamá Hotel Free Parking

Welcome to the beautiful Aloft Panamá hotel This is a very nice and safe hotel located in the San Francisco area of Panamá with beautiful city views. King or 2 queen based on availability (Feel free to make request prior to booking if you have a preference) All rooms non smoking ($350 fine) No pets allowed Must be 21 with id to checkin Must have credit card for incidentals Checkin time starts at 3pm Checkout time before noon Free Parking Pool Bar/Lounge

An outdoor terrace features several lounge chairs and tables shaded by large umbrellas. A swimming pool extends along one side, with a backdrop of modern high-rise buildings under a partly cloudy sky. Lush greenery is present in planters, adding a touch of nature.

Hotel room in Panamá

4.83 out of 5 average rating, 6 reviews

En el corazón de la ciudad.

Hotel Mio Panamá somos un hotel 4 estrellas situado en la ciudad de Panamá, en el corazón del área financiera. Nuestro principal objetivo es satisfacer cualquier necesidad del cliente, ofreciendo los mejores servicios para garantizar una estancia cómoda y tranquila. Entre nuestras modernas instalaciones, encontrará una piscina, habitaciones amplias y cómodas, gimnasio, salas de reuniones y rooftop. Si le gusta viajar con su mascota, somos pet friendly.

A circular pool is surrounded by lush greenery, including vibrant flowers and palm leaves. A person in swimwear stands in the shallow water, with arms raised, creating a lively focal point. The pool is equipped with a ladder for easy access.

Private room in Panamá Oeste

5 out of 5 average rating, 3 reviews

Iwanna Green Ecolodge Habitación con Baño privado

Descubre tu oasis eco-amigable en el corazón de un hermoso entorno natural. Nuestra habitación con baño privado ofrece: Cama Full más sofá-cama Full Baño amplio, privado, con amenidades eco-amigables Ventanas con vista al jardín, ideal para relajarte Wi‑Fi gratuito de alta velocidad Desayuno saludable incluido (tostadas, huevos, frutas de temporada / café y más ) Espacios comunes: terrazas, piscina, espacios para descanso y más

A cozy hotel room is showcased with a spacious bed dressed in white linens and a red throw blanket. A wooden desk with two cups and a remote is positioned beside the bed. A soft lamp and a wall-mounted TV complete the inviting atmosphere.

Hotel room in Panamá

4.71 out of 5 average rating, 31 reviews

Cuarto de hotel #3 a una cuadra del Metro.

Disfruta de acceso ràpido a los destinos más populares de Ciudad de Panamà, centros comerciales, restaurantes, y áreas turísticas. Cuarto de hotel con baño privado, aire acondicionado, cable TV, recepciòn con 24 horas de servicio y estacionamientos sujetos a disponibilidad. Cerca de restaurantes y casinos. A una cuadra de la estaciòn del Metro que lo lleva en 10 minutos a Albrook Mall, el Centro Comercial más grande de Panamà.

A close-up view of vibrant purple bougainvillea flowers is presented alongside a well-maintained pathway, leading to a charming building with arched windows and a wooden front door. Green foliage frames the entrance, enhancing the welcoming atmosphere.

Hotel room in Panamá

4.86 out of 5 average rating, 43 reviews

Habitaciones privadas Sofia's B&B Hostal Boutique

Alojamiento tipo hostal boutique, contamos con 7 cómodas habitaciones privadas con baño, para una capacidad total de 18 huéspedes. La tarifa mostrada por Airbnb para tu reserva distribuye 2 huéspedes por habitación, es decir, los huéspedes deberan compartir camas y/o habitaciones. Si requieres una distribución especial de habitaciones para tu grupo, contacta primero con el anfitrión, ya que la tarifa podría variar.

A cozy sleeping area features a plush bed with a light-colored quilt and dotted pillows. A bedside table holds a small lamp, providing soft lighting. The wall is adorned with a unique decorative panel, and a ceiling fan offers comfort.

Private room in Panamá

4.82 out of 5 average rating, 22 reviews

Desk & Dream Room

Disfruta de la comodidad de este alojamiento tranquilo y céntrico en el corazón de San Francisco, tiene escritorio dentro de la habitación para trabajar o estudiar en un ambiente relax, con las demás comodidades incluyendo televisor led HD de 32" Justo en la calle de al lado está el super mercado, farmacia al frente, restaurantes, tiendas de chinitos, panaderías, paradas del metro bus cercanas.

Large green doors open to a charming balcony, revealing a view of a red-tiled roof and a small table with two chairs. A soft sofa is positioned nearby, complementing the inviting atmosphere of the space.

Hotel room in Panamá

4.85 out of 5 average rating, 102 reviews

Corcho rooms #2 - king room with balconies

Enjoy charming “Corcho rooms” in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant an serviced guest rooms upstairs. “Corcho” is luckily situated in the central, restored part of Casco. Most of the building around are restored and the neighborhood is safe.

Vacation rentals for every style

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Stylish accommodations with great services and amenities

Popular amenities for Panama Canal hotel rentals

Free parking on premises

Air conditioning

Family-friendly hotel rentals

A simple sleeping area features a spacious bed covered with a light blue blanket and white pillows. The wall unit holds a television, and a chair is positioned nearby. Dark curtains cover the window, contributing to the serene atmosphere of the room.

Hotel room in Colón

4.8 out of 5 average rating, 5 reviews

Meryland Hotel

A sleeping area features a spacious bed with a neutral-toned cover and a dark blue blanket folded at the foot. Simple wooden nightstands are mounted on either side, each equipped with bedside lighting. Soft natural light filters through a sheer curtain over a window.

Hotel room in Panamá

4.68 out of 5 average rating, 73 reviews

Tu segundo hogar en Panamá.

A vibrant yellow building is set against lush greenery, featuring multiple levels and spacious balconies. A refreshing plunge pool is surrounded by wooden decking, with colorful umbrellas providing shade. Lounge chairs in varying colors invite relaxation while flowers add a natural touch to the scene.

Private room in Taboga Island

4.66 out of 5 average rating, 53 reviews

Eco Lodge Garden Room 4, Oceanview Plunge Pool

A vibrant yellow building is visible amidst lush greenery, complemented by a clear blue sky. Colorful umbrellas shade the outdoor seating area around a turquoise pool, featuring wooden decking and various chairs. Tropical plants add to the natural surroundings.

Private room in Taboga Island

5 out of 5 average rating, 5 reviews

Eco Lodge Mango Room 3 Queen Plus

A hotel room featuring two spacious beds with soft bedding, complemented by a gray accent wall. A desk and chair are positioned near the window. The door to the hallway is visible in the background, along with a flat-screen television mounted on the wall.

Hotel room in Panamá

4.4 out of 5 average rating, 5 reviews

Double Deluxe

The sleeping area features two beds with decorative blue and white patterned bedspreads. A bedside table holds a telephone. Natural light enters from the window, accompanied by light curtains and deep red drapes. The walls are finished in a neutral tone.

Hotel room in Panamá

4.78 out of 5 average rating, 80 reviews

Habitación Familiar Triple sencilla

A tranquil pool area is surrounded by lush greenery, with palm trees and tropical plants creating a serene environment. Colorful circular seating stones are arranged near the edge of the pool, inviting relaxation. The pool's clear water reflects the sunlight, enhanced by the natural landscaping.

Private room in Panamá

4.65 out of 5 average rating, 46 reviews

El Canal

The exterior features a warm yellow facade with a large arched window and distinct wooden door, complemented by a neatly landscaped flower bed. Paved pathways lead to the entrance, providing a welcoming approach to the boutique hostel.

Hotel room in Panamá

4.75 out of 5 average rating, 12 reviews

Alojamiento entero Sofia's B&B Hostal Boutique

Hotel rentals with a pool

A spacious Jr Suite features a large bed adorned with colorful pillows, complemented by natural wood accents. A small wooden table and chairs are positioned nearby. A ceiling fan circulates air in the bright room, which is illuminated by a striking lamp and natural light from a doorway.

Hotel room in Panamá

4.25 out of 5 average rating, 4 reviews

Jr. Suite Rm #3- Cerro Azul

Hotel room in Panamá

4.42 out of 5 average rating, 19 reviews

Rainforest Suite with Breakfast! 15 min from city

A well-appointed sleeping area is equipped with two spacious beds, each dressed in crisp white linens and topped with red accent blankets. Soft lighting is provided by wall-mounted lamps, and floor-to-ceiling curtains frame the window, adding privacy and warmth to the space.

Hotel room in Panamá

4.77 out of 5 average rating, 13 reviews

Suite Doble-Apartamento Hotel Príncipe

The room features two neatly made single beds dressed in soft beige bedding, placed side by side. A window provides natural light, complemented by a wall-mounted light fixture. The modern floor is tiled in a light gray finish, contributing to a minimalist aesthetic.

Hotel room in Panamá

3.89 out of 5 average rating, 9 reviews

Habitación privada 2 camas twin

A spacious bedroom is presented with a large bed, complemented by soft pillows and a neutral bedspread. A small circular table with two upholstered chairs is positioned nearby. A large window allows natural light to fill the room, enhancing the warm red wall.

Hotel room in Panamá

Excelente habitación privada

A cozy bedroom features a spacious bed dressed in a light blue quilt. Two bedside tables with soft lamps flank the bed, providing gentle illumination. A green accent wall and a piece of leaf-themed artwork add a touch of natural beauty to the room.

Hotel room in Panamá

Tropical Tranquility - Coconut Lodge

An infinity pool stretches towards the horizon, offering unobstructed views of rolling hills and a serene landscape bathed in soft sunset hues. The smooth water appears to merge with the sky, while a stone patio surrounds the pool area, enhancing the tranquil setting.

Hotel room in Campana

4.68 out of 5 average rating, 19 reviews

Queen Room3 at Vida Lotus Retreat & Spa, Limon, PA

A spacious room features a neatly made bed with soft linens and two pillows. A flat-screen TV is mounted above a dark wood cabinet. A window is covered by dark curtains, while an air conditioning unit is positioned on the wall.

Hotel room in Colón

4.25 out of 5 average rating, 4 reviews

Meryland Hotel

Hotel rentals with a patio

A spacious sleeping area features a four-poster bed dressed in neutral linens, accented by a vibrant red pillow. A comfortable red couch is positioned near large glass doors, which provide natural light and views of the surrounding greenery.

Private room in Panamá

4.75 out of 5 average rating, 4 reviews

Harpy Eagle Room in Treehouse

A spacious room features a queen-sized bed with a light-colored duvet and decorative pillows. A large window with sheer curtains allows natural light to brighten the space. A small bedside table with a lamp and an art piece adorn the wall, complemented by a minimalist clothing rack.

Private room in Panamá

New place to stay

Double Studio - Viajero Hostels

A modern room features a spacious bed with neutral bedding, complemented by a light-colored accent wall. A small dining table with two chairs is positioned near a floor-to-ceiling window, which is framed by soft curtains. A flat-screen TV is mounted on the opposite wall.

Hotel room in Panamá

5 out of 5 average rating, 3 reviews

Eshel Panama Suites, Atlantic suite 04

Hotel room in Panama City

New place to stay

Pekin Room in the ORHO Hotel

A small sleeping area features light green walls and a cozy bed with a striped linen cover. A single window is partially draped with green curtains, allowing natural light to illuminate a potted plant positioned on the windowsill.

Private room in Panama City

4.67 out of 5 average rating, 12 reviews

El Tornillo semi-private space.

The bright sleeping area features two double beds with stylish headboards and decorative accent pillows. A textured area rug is placed on the hardwood floor. Natural light floods the room through large windows with sheer curtains, complementing the exposed brick wall.

Hotel room in Panamá

Charming Studio w Two Double Beds

A three-level villa is shown, featuring a bright yellow exterior with blue roofing. Large windows allow natural light to fill the space. Surrounded by lush greenery and tropical plants, a driveway with a vehicle is visible, enhancing the property’s inviting atmosphere.

Casa particular in Panamá

La Husseyenda- Birdwatcher Haven

An outdoor pool is illuminated in a calming blue hue, surrounded by lounge chairs. Umbrellas provide shade, while plants add a touch of greenery. The night sky and distant hills create a serene backdrop, enhancing the tranquil atmosphere of the space.

Hotel room in Taboga Island

Taboga Palace Hotel. Beach front English Bouquet

Destinations to explore