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Vacation rentals in Obregon

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Obregon

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
Guesthouse in Yuma
4.95 out of 5 average rating, 123 reviews

Relaxing 2 Bedroom Attached Guest House

Stylish and relaxing attached 2Bedroom Guest house.Quiet neighborhood 5 min away from Onvida Yuma Regional center 4 min from Walmart,Starbucks and fast food restaurants. You will also have access to the shared pool and backyard.Pool is not heated but is available all year.Fully stocked kitchen,stacked washer & dryer in unit for your convenience.This apartment is adjacent to another airbnb property.Complete apartment is 100% private.Access to shared pool and backyard. Max guest occupancy 4 people

Guest favorite
Home in Yuma
4.95 out of 5 average rating, 136 reviews

Yuma’s Best | Pet Friendly | Snowbirds Welcome

Modern desert retreat in the clean, quiet Lynwood neighborhood of Yuma. Open layout with high ceilings and dome skylights that bring in natural light without added desert heat. Ideal for snowbirds, families, traveling professionals, and guests visiting Algodones for dental care (18 mins). Pet-friendly with private backyard patio—perfect for relaxing mornings and evening grilling. High-speed reliable WiFi, Spectrum cable TV + streaming. Close to shopping, golf, dunes, and Los Algodones, MX.

Guest favorite
A spacious living area features dark, comfortable seating arranged around a round coffee table. A large television is mounted on the wall opposite the seating. Light-colored tiles cover the floor, while natural light filters through the window with horizontal blinds.
Home in Yuma
4.96 out of 5 average rating, 23 reviews

Entire Home In Yuma Arizona

Upgraded super central 4 br, 2 bath You're just 10 min from the airport, 5 min to the hospital & Marine Corps Air Station, 15 min to the Los Algodones border, and 10 min to downtown Yuma. This comfy, spacious home is great for families, friends, or even solo travelers, it’s the perfect home base to relax and explore all that Yuma has to offer. This House offers you a large, comfortable home ideal for large groups, Your group will enjoy easy access to everything from this centrally located.

Guest favorite
Place to stay in Yuma
4.87 out of 5 average rating, 189 reviews

Adobe Encanto “house”

Beautiful & Historic Spanish-Style Home Built in 1925, this charming Spanish-style home is part of Yuma’s rich history. Recently renovated, it blends historic character with modern comfort, featuring vibrant décor, and a lush garden perfect for relaxing with family and friends. The property sits on a large lot. A fenced backyard separates the home from a charming tiny house, which is also an Airbnb. Both accommodations are completely private and do not share any indoor or outdoor spaces.

Guest favorite
A cozy living area features a mustard-yellow sofa adorned with decorative cushions. A round, metallic coffee table is positioned on a colorful area rug. Wall art and plants provide decorative touches, while a mounted television offers entertainment options.
Condo in Vicente Guerrero
4.97 out of 5 average rating, 76 reviews

Los Algodones Dental Stay | Upstairs 2BR + Parking

Perfect for dental visits in Los Algodones. This clean and quiet upstairs 2BR unit is minutes from the dental clinics — no car needed. Each bedroom has a private bathroom for comfort and privacy. Enjoy a full kitchen, WiFi, Smart TV, secure parking, laundry access, and easy self check-in. Great for couples, friends, or small families visiting for dental appointments. Please note: This is an upstairs unit and guests must use stairs. For a ground-floor unit, please check our other listing.

Top guest favorite
A dining area features a large wooden table adorned with a vibrant arrangement of red flowers in a white vase. The space is illuminated by a rustic chandelier, and a decorative wall displays the name 'The Dandy House' beside a barn-style door.
Home in Yuma
4.99 out of 5 average rating, 134 reviews

The Dandy House: A Stunning 3-Bedroom Charmer

This property is an extension of our local boutique in Yuma, Dandy Home and Ranch. Enjoy a stylish and cozy stay, as Dandy invites you to experience hospitality and inspiration, whether you are traveling for work or for pleasure. We are located just down the street from the hospital, and we are just steps away from Starbucks, and other convenient amenities. We invite you to relax in the backyard by the fire pit, cook an amazing meal, or cozy up by the fireplace, all in Dandy style.

Top guest favorite
Home in Yuma
5.0 out of 5 average rating, 41 reviews

Yuma Valley Atrium Retreat

Bring the whole family or crew to this great place with lots of room for fun. Pool is not heated. We have four bedrooms; each has a private bathroom. Primary suite has a king bed and a walk-in shower. We have three TVs w/ Roku access, games, and puzzles. The office has a TV, futon couch, and a piano. Back yard includes pool with a slide & diving board, BBQ grill with table & chairs. Counter seats 4 and the dining table has 8 chairs. There are a port-a-crib and high chair available.

Guest favorite
A single-story home is presented with a tiled roof and stone accents. Lush greenery frames the entrance, with gravel landscaping surrounding the property. A driveway leads to a garage, and a rock feature adds a natural element to the front yard.
Home in Yuma
4.83 out of 5 average rating, 127 reviews

Large beautiful 3 bedroom pool home

Located in a beautiful and quiet subdivision this home boasts a large floor plan with plenty of room for a group of 10 and a sparkling pool. We’ve put a lot of thought into your stay with amenities like cold drinking water, a BBQ and washer and dryer to help you enjoy your stay, relax and unwind. Throw in a bath bomb (provided) and enjoy a soak in the tub or lay out pool side with a glass of wine. Master holds a king bed, 2nd room a queen, and 2 bunks with trundles in the 3rd.

Top guest favorite
A spacious bedroom features a comfortable bed dressed in neutral tones with decorative pillows. Two mirrors reflect natural light from a window framed by simple blinds. A textured rug complements the wood flooring, while a dresser and nightstands add functional decor.
Home in Yuma
4.98 out of 5 average rating, 250 reviews

Tuscany Style Casita

Discover a newly remodeled Tuscany-style casita that feels like a quiet Italian escape in the heart of Yuma. Thoughtfully furnished for up to four guests. This two bedroom casita is truly cozy and warm. The neighborhood is safe, quiet and well kept. We are centrally located with Onvida hospital 5 min away, 10 min to the airport, 10 min to Yuma Palms and downtown and just minutes from Sprouts, Starbucks, Bubba's 33, local restaurants and more. We offer gated private parking.

Top guest favorite
A compact studio features a cozy seating area with a small sofa and a sleek side table. A wall-mounted television displays a flickering fireplace. A table with two chairs is positioned nearby, with additional decor on the walls, including framed artwork and decorative plates.
Guest suite in Yuma
4.96 out of 5 average rating, 76 reviews

Tiny Arty Studio

Welcome to our cozy, compact studio, designed with both short and extended stays in mind. Enjoy complete privacy with your own entrance and a secluded patio, perfect for unwinding. Situated just 25 minutes from Algodones, you’ll find our location both convenient and peaceful, offering a serene neighborhood for a restful retreat. With easy access to hospitals, schools, and shopping areas, it’s the perfect spot for both relaxation and convenience.

Guest favorite
Home in Yuma
4.79 out of 5 average rating, 115 reviews

Private Pool Retreat | 3BR Home Sleeps 8 | Firepit

Welcome to your perfect getaway! This stunning 3-bedroom, 2-bathroom home features a beautiful private pool, ideal for families and friends looking to relax and unwind. Nestled in a peaceful neighborhood, our home combines comfort and convenience, making it the perfect base for your vacation. Outdoor propane grill available for guest use. Propane is not provided; guests are responsible for refilling/exchanging the tank if needed

Guest favorite
A cozy living area showcases a comfortable seating arrangement with a gray sectional and a wooden coffee table. A television is mounted on the wall, while a dining space is highlighted with a glass-top table surrounded by six chairs. Soft lighting and neutral tones create a welcoming environment.
Home in Yuma
4.91 out of 5 average rating, 217 reviews

House 2 bedrooms with/swimming pool

Enjoy your stay at "My Saguaro Casita" Has a beautiful pool, new air conditioning unit, a very comfortable home centrally located in Yuma, near the free way and close to Algodones and shopping centers. It offers you Outside and Inside options for entertainment with family and friends. Come and enjoy our home away from home.

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