Villa vacation rentals in Mission Beach, San Diego

Find and book unique villas on Airbnb

Top-rated villa rentals in Mission Beach, San Diego

Guests agree: these villas are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Superhost

Villa in San Diego

4.94 out of 5 average rating, 18 reviews

Sanctuary 4BR Church & Deck Near Downtown (18 ppl)

This is a unique rental, which combines the convenience of vacation rentals with event spaces to enjoy. Like a hotel suite but with a large yard, you will have plentiful areas to enjoy for your stay. 6 bedrooms at our resort with a central meeting space that is a historic church from 1909 designed by innovation and renowned architect IRVING GILL. He created the building that we renovated and now call "" The SANCTUARY"". All rental houses & event spaces are within our acre-wide resort. -----

Guest favorite

Villa in Allied Gardens

4.91 out of 5 average rating, 22 reviews

Fun Get Away, Vaulted Ceiling, Pool, Hot Tub, New.

Enjoy a stylish experience at this centrally-located place. Great place to stay for those seeking an experience close to the beach and mountains and anywhere in San Diego you'd like to visit. 5 min from trails and Cowles Mountain. 15 min to Sea World, Animal Park, beaches, parks, downtown, Balboa park, the Midway museum, Coronado, Torrey Pines, La Jolla Cove, and much more! 2 min to a kid playground. Nice Villa in a really nice and Quiet Neighborhood, but will also accommodate your best party!

Guest favorite

Villa in Mission Hills

4.92 out of 5 average rating, 51 reviews

1stResorts.com AMAZING WATER VIEW PENTHOUSE HOTTUB

GORGEOUS NEW BREATHTAKING WATER VIEW VILLA! Great for quiet EXECUTIVES FOR LONGER TERM STAYS, COUPLES, FAMILIES, FRIENDS & INDIVIDUALS! Beautiful sparkling water of San Diego Bay to Pacific Ocean from ENTIRE IMMACULATE EXCLUSIVE PENTHOUSE! DESIGNER DECOR/PRIVATE Hot tub/very own Oasis! No need to venture out, everything you need/want on property! All comforts of home & more w/5 star LUXURY RESORT experience! PRIVATE DECK BarBQ & FirePit! Close to everything/BEST AREA/DEEP DISCOUNTS LOWEST RATES!

Top guest favorite

Villa in San Diego

4.98 out of 5 average rating, 51 reviews

Lux Villa: Heated Pool, Sauna, & Gym

Nestled in the heart of SD, the luxurious four bedroom stands as a modern marvel. Entering the grand foyer, you're greeted by fireplace that ads a touch of warmth to the ambiance and bose surround sound system that ensures every moment is accompanied by the perfect soundtrack. Queen-sized beds, deep soaking tub and rain showers in all three bathrooms. Outside, a sprawling terrace with a sparkling heated pool, enhanced swim jet, a cascading waterfall and sauna that adds to the serene ambiance.

Guest favorite

Villa in El Cajon

5 out of 5 average rating, 66 reviews

Zen Resort w Infinity Pool/Spa/Casita+360° views

Relax, rejuvenate, revive & re-ignite at this magnificent & blissful estate on over an acre of land with jaw dropping panoramas of dreamy Socal landscape! A superb year round temperature controlled Infinity edge pool & Spa with some of the most striking views transform this estate into a private resort. A Mexican hacienda style solitary villa set on a hilltop of a private hill, secluded, quiet, undisturbed with plenty of space for large groups. 15 minutes to downtown San Diego attractions.

Superhost

Villa in Downtown

4.82 out of 5 average rating, 49 reviews

TuCasa | Luxury 4 Story Villa in Little Italy

Welcome to San Diego! Take in the spectacular rooftop views from your stunning home in the heart of Little Italy. Spend days and nights relaxing on one of the many outdoor patios that offer plenty of space for entertaining. Fire up the BBQ, and stay warm by the fire pit as you sip on some wine while the sun sets. The beautifully designed interior features bright and eclectic details, adorned with maple flooring. This hideaway is the ultimate destination for your group travel in San Diego!

Superhost

Villa in Logan Heights

4.73 out of 5 average rating, 11 reviews

Bella Casa | Pool, Spa, King Bed, AC, Min to Dtown

Escape to this charming 2BR, 1BA home in the heart of San Diego! Enjoy a king-size adjustable bed, full-size bed, futon, and sofa bed. Stay comfortable with central AC & heat, resort-style amenities—pool, jacuzzi, outdoor lounge, and grill. The driveway fits two tandem cars and an electric gate for convenience. Shared laundry, plus a pack-and-play & high chair for little ones. Minutes from top attractions, beaches, dining, and airport access. Book now for the perfect San Diego getaway!

Superhost

Villa in Point Loma Peninsula

4.81 out of 5 average rating, 36 reviews

Historic Villa, Blocks from the Beach, Ocean Views

Built in 1923, this beach town retreat has tons of old world charm with all the modern amenities. Only 6 blocks to the beach, you couldn't ask for a better location. Dog Beach, Sunset Cliffs and some of the best bars, restaurants and vintage shops in all of San Diego are just outside your doorstep. ☞ 3 Bedrooms ☞ Private Hot Tub ☞ Private Swimming Pool ☞ Outdoor Dining ☞ Ocean Views (perfect for sunset cocktails) ☞ Outdoor Grill ☞ Bikes to enjoy the neighborhood ☞ Chef's Kitchen

Guest favorite

Villa in San Diego

4.96 out of 5 average rating, 26 reviews

Hillside Retreat | Pool, Game Room, Sunset Lounge

☀️Welcome to your luxurious San Diego getaway! ☀️ This spacious 5-bedroom, 2-bathroom 2-level home is perfect for groups and families. Dive into the sparkling blue pool, unwind in the 6-person hot tub, or relax in the cozy outdoor seating areas. Enjoy stunning views from the balcony overlooking the pool, perfect for sunsets. With a central location, plenty of space to relax, and a mix of comfort and elegance, this home is ideal for exploring or unwinding on your San Diego adventure!

Guest favorite

Villa in Ocean Beach

4.96 out of 5 average rating, 45 reviews

Gorgeous Beach Villa | Ocean Views + Sleeps 12!

Experience the ultimate family retreat in our spacious 6-bedroom, 4-bath home with breathtaking views of Mission Bay and the Pacific Ocean. Perfect for groups, it features two kitchens, multiple balconies, and a large backyard with a fire pit and grill. Walk to Ocean Beach and Sunset Cliffs or explore nearby attractions like SeaWorld and Balboa Park. Unwind with sea breezes, sunsets, and the sparkle of SeaWorld fireworks. Your unforgettable San Diego getaway starts here!

Top guest favorite

Villa in Mission Hills

4.99 out of 5 average rating, 80 reviews

Hidden Villa with Beautiful Furnished Garden Patio

Close to everything, quiet and private. This beautiful 2 Bd Villa seems to be loved by all who stay here. The outdoor private patio feels like your in the forest. Gorgeous custom bath with large marble shower. Full size laundry. Great entertainment system,DVD's, Roku, Amazon Prime. The home has open beam ceilings, lots of light and a fabulous patio fully furnished for guests, outdoor dining and barbecuing. The home is private, fenced, furry friends are welcome.

Guest favorite

Villa in Hillcrest

4.74 out of 5 average rating, 43 reviews

Vintage Home on the Canyon’s Edge

We are offering our beautiful house in University Heights (about 5 minutes from downtown San Diego). The house rests on the edge of a canyon with trees and nature surrounding the home. House has 2 bedrooms, a study which could be used as a bedroom, and 2 bathrooms. We have Wifi, a smart TV, and a washer and dryer. Kitchen is fully equipped. There is a balcony facing the canyon that overlooks our hot tub below. You will love this cozy home.