
Hotels in Middlesex County
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Top-rated hotels in Middlesex County
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Longwood Area | Perfect for Long Stays & Visits
Stay in a charming 1886 Victorian home in the heart of Brookline, Boston. Perfect for long stays, with cozy parlors and timeless charm. 🏡 Location & Accessibility Public Transport Nearby: Just a block from Saint Mary's Street Station, offering easy access to downtown Boston and surrounding areas. Restaurants & Local Shops: The vibrant Coolidge Corner neighborhood is only about 1 mile. Museums & Cultural Attractions: Fenway Park, Boston’s iconic baseball stadium, is about 1.2 miles away.

Timeless Stay | Freedom Trail. Fitness Center
Explore a beautifully reimagined luxury hotel, The Newbury Boston, where the bustle of the Back Bay is your playground and the idyllic Boston Public Garden your front yard. Attractions just nearby: ✔Boston Expressionist paintings and Chinese ceramics at Museum of Fine Arts ✔Deep dive into history at Boston’s Tea Party Museum ✔Sharks, rays, penguins at New England Aquarium ✔400 years of Boston’s history and the story of nation’s pursuit of liberty, Freedom Trail ✔Downtown Boston

Close to campuses & large mall with dining options
The Residence Inn Natick is the perfect location for guests visiting both Natick, Framingham and Newton. Close to area colleges and universities, our hotel is centrally located just minutes outside Boston. - Walking distance to Natick Mall, PuttShack and many restaurants. - Nearby to Logan Express with express bus service to Logan Airport - Free Breakfast Buffet - Hand-Crafted Cocktails in our Lobby and Lounge - Electric car charging stations - Fitness Room - Full kitchen in each room

Harvard/MIT, Charming private rm +kitchen access
This quiet, peaceful room in Inman Square is a great choice for your next trip to Cambridge/Boston. It is centrally located—a 10-to-15-minute walk to Harvard, MIT, Central Square, and the tech companies around Kendall Square. Whole Foods, Koreana, S&S Deli, local microbreweries, and many more food options are within blocks. This private room shares a bathroom with one other room. Access to the kitchen and deck and also included. An economical “get away” in the heart of Cambridge.

Inn at Newton Highlands, Suite 1, Apartment-Hotel
This gorgeous 2 bedroom, 2 1/2 bathroom suite at The Inn at Newton Highlands is pure luxury. It features a large and inviting living room, spacious bedrooms with private bathrooms, a private 500 sq.ft. deck, and everything else to make your stay comfortable and memorable. The suite has its own HVAC system. This suite is one of several luxury suites in a small boutique Inn which is located in the heart of Newton Highlands in a beautiful, fully remodeled historic building.

Walk to Fenway Park + Free Breakfast & Pool
Stay steps from Fenway Park in a hotel that lives and breathes rock ‘n’ roll. At The Verb, you’re not just checking into a room—you’re stepping into a retro-cool experience with a vinyl library, record players in every room, and a year-round outdoor pool. Whether you’re catching a game, exploring Boston’s iconic music scene, or sipping cocktails poolside, this stay is anything but ordinary. It’s fun, loud (in a good way), and full of personality—just like the city around it.

Steps from the T & Museum of Science
The Fairfield Inn and Suites Cambridge is the perfect location for guests visiting both Cambridge and Boston. Close to MIT and Harvard Universities, the TD Garden and a short walk to the T for subway rides into Downtown Boston. - 24/7 Front Desk support - Free Wi-Fi - Free breakfast buffet daily - Housekeeping service - Mini-refridgerator/Microwave/Private Bathroom in each room - Market on-property for anything you forgot or need - Fitness Room - Parking (daily fee)

Close to Fenway Park | Gym. Bar. River View.
✨ Hip Vibe, Great Location Right in the buzz of Boston’s Theatre District, this playful downtown escape is made for city lovers and night owls. Step out to catch a Broadway show, stroll through Boston Common, or hit the nearby bars and music spots. Back at the hotel, chill with a cocktail, meet new friends in the lounge, or rest up in your smart, stylish room with skyline views. Perfect for travelers who crave energy, creativity, and that signature social vibe.

Beacon Hill - Historic Elegance
Step into the crown jewel of 40 Hancock Street, a grand Beacon Hill brownstone suite with soaring ceilings, ornate fireplaces, and elegant bay windows that flood the space with light. This historic yet modern retreat blends timeless Boston charm with upscale finishes. Just steps from Boston Common, the Charles River, and the city’s finest dining, this luxury unit offers an unforgettable stay in one of the city’s most iconic neighborhoods. 🚫 No pets allowed

Great central location in Downtown Boston
The Residence Inn Roxbury South End is the perfect location for guests visiting Boston. Close to area colleges, universities, and hospitals including Mass General, our location makes it easy to explore Boston. - Walking distance to restaurants and shopping - Free Breakfast Buffet - Hand-Crafted Cocktails nightly in our lobby lounge - Valet Parking available (nightly fee applies) - Fitness Room - Full kitchen in each room

Harborside Inn-Boutique Hotel
Originally built in 1846 as a mercantile shipping warehouse on the Boston Harbor. Here, a modern design with a nautical theme is accented with the latest high technology amenities to satisfy the most savvy business or leisure traveler. Premier location. Exceptional value. Stylish decor. The Harborside Inn combines it all to create a unique lodging experience.

Private oasis on Boston's historic waterfront
Find your urban refuge in Boston. Unwind in a stylish room complete with Seaport's signature pillowtop mattresses and: Complimentary Wi-Fi 55" HD TV with 55 channels, Netflix and streaming content Bedside reading lamps, USB ports and power Two complimentary bottled waters daily Keurig® Coffee Makers with coffee and tea Mini-fridge Laptop size safes
Popular amenities for Middlesex County hotels
Family-friendly hotels

Harvard/MIT Peaceful rm +private BR +share kitchen

New England Charm | Hiking. Restaurant

Near sports event and concert venues

Harvard/MIT, Private rm +private BR +share kitchen

Double Queen - Non smoking

Vacation is Calling! w/ Indoor Pool, Pet-Friendly

Extended Stay Boston | Room |Longwood Medical Area

Inn at Newton Highlands, Suite 3, Apartment-Hotel
Hotels with a pool

Close to Brandeis University + Pool. Dining. Gym.

Close to Harvard University + Pool. Lounge. Gym.

King Bed | Pet-Friendly. Free Breakfast & Parking

2x2 Your Ideal Retreat in Westborough - Boston

Spacious Tranquility: 2-Bedroom Haven

Steps from Fenway Park + Free Breakfast & Pool

1 King Bed | The Fifth Andover | Free Breakfast

King Bed | Ramada Boston | Access to Fenway Park
Hotels with a patio

New Suite Marlborough-Boston

Harvard/MIT, Art-filled private rm +en-suite bath

Staybridge Suites -2 Rooms 3 beds Suite

Cedar & Brick on the Hill

A very nice and spacious room

The Lantern on Beacon Hill

Coelina’s Castle

Moonlight Beacon Hill Sonata
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- Hampton Beach
- Fenway Park
- TD Garden
- Boston Common
- Harvard University
- Revere Beach
- Brown University
- Lynn Beach
- Monadnock State Park
- New England Aquarium
- MIT Museum
- Good Harbor Beach
- Freedom Trail
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- Museum of Fine Arts, Boston
- Jenness State Beach
- Quincy Market
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- Prudential Center
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- Salem Willows Park
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