
Vacation rentals in Knob Lick
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Top-rated vacation rentals in Knob Lick
Guests agree: these stays are highly rated for location, cleanliness, and more.

Spring Valley Ranch Rock House
This quaint farmhouse is located just off of MO Hwy 72 on a 62 acre farm nestled against the Castor River. Here you and your companion(s) can experience the quiet and relaxing life on a farm with plenty of adventure awaiting just around the bend. Sit and enjoy a sip of coffee or tea on the front porch while watching the cattle graze the pasture across the road next to a rustic white barn or venture about 3 miles to the largest privately owned lake in Madison County. Oh yes, enjoy your stay!
ValueLocationGetting around
4.96 out of 5 average rating, 212 reviews
Cozy 2-Bedroom Log Cabin With Wood Burning Stove
Escape to this peaceful and unique log cabin nestled in the woods, overlooking a beautiful 1.5-acre pond. Whether you’re looking for a quiet weekend getaway, a fishing retreat, or a relaxing trip to explore the local wineries, this cozy cabin offers the perfect blend of comfort and tranquility. The cabin comfortably sleeps four guests, with an additional hideaway bed available for extra sleeping space. Slow down, unplug, and experience the charm of cabin life in a serene countryside setting.
FamilyLocationDecor
4.94 out of 5 average rating, 50 reviews
Loft in Historic Downtown
Experience the charm of historic downtown Farmington, MO in this stunning 2-bedroom, 1.5-bath loft! Perched on the second floor of a late 1800s building, meticulously rebuilt in 2018, it blends vintage elegance with modern comforts. Enjoy a private entrance for ultimate privacy. Nestled in the heart of the historic district, steps from the courthouse, boutique shopping, and delightful dining. Perfect for couples or small families seeking a cozy, walkable getaway. Book your slice of history!
FamilyLocationAccess
5.0 out of 5 average rating, 29 reviews
Sweet Magnolia House Sleeps 8-Large Fenced Yard
Welcome to our charming home in the heart of downtown Farmington. Perfect for families or groups, our spacious three-bedroom house comfortably sleeps eight guests and features two full bathrooms. The home is fully furnished and includes a washer and dryer on a double lot with privacy fence. Located near Elephant State Park, Johnson's Shut-Ins, Bonne Terre Mines, Shepard Mountain Bike Park, St. Joe State Park, and Wineries. Or stroll downtown where you can enjoy local shops, and restaurants.
LocationFamilyAmenities
4.95 out of 5 average rating, 64 reviews
The Clementine Cottage-One Bedroom Secluded Home
Nestled in the heart of the Missouri Ozarks, this peaceful one-bedroom retreat offers the perfect mix of seclusion and adventure. Located between Fredericktown, Farmington, and Arcadia, you’ll feel tucked away in nature while staying close to top outdoor attractions. Explore Elephant Rocks, cool off at Johnson’s Shut-Ins, enjoy local whitewater events or ride the trails at Shepherd Mountain. Whether you’re here to hike, bike, float, or relax, this cozy getaway is the perfect home base.
LocationFamilyIndoor spaces
5.0 out of 5 average rating, 22 reviews
Private Treehouse Retreat | Hot tub
The TreeLoft is the first of two treehouses at BaseCamp—designed for cozy seclusion, romance, and rest. Nestled in a private forest just 1 hour from St. Louis, it blends upscale comfort with immersive nature, while still being 20–35 minutes from hiking, wineries, and dining. ✨Our NEW treehouse, The TreeRise, offers an even more elevated, spacious experience at BaseCamp. Perfect for romantic getaways, anniversaries, personal retreats, and intentional escapes to unplug and reconnect.
LocationFamilyEV charging
5.0 out of 5 average rating, 721 reviews
Hot tub/ Blissful Beaver River Cabin
Remodeled remote cabin with an antique modern feel, large deck overlooking the St.Francios River. Soak your cares away in the Hot Tub. The river is great for kayaking and fishing. Enjoy a peaceful nature get away. Bring your fishing poles, a book, kayaks and disconnect from the hustle and bustle of everyday life! We’re close to Silver Mines, Millstream Gardens, Taum Sauk Mountain, Amidon Conservation, Elephant Rocks, only 10 miles to Ironton or Fredericktown for food and drinks!
ValueLocationKitchen
4.89 out of 5 average rating, 335 reviews
Picturesque country home
📣 Airbnb fee now incld. in nightly rate! 📣 Escape to the scenic fully remodeled black log cabin on 74 secluded acres. Enjoy stunning valley views from the wrap around porch and a private stocked pond. Whether you're seeking a romantic getaway, a family weekend, a retreat, or a gathering of friends, our scenic cabin is the perfect destination. Book your stay today and experience the serenity and beauty of this secluded oasis that promises to rejuvenate your mind, body, and soul.
LocationFamilyBackyard
4.96 out of 5 average rating, 24 reviews
The Caamp
The Caamp located directly across the road from The Barn at Lone Eagle Landing and Pebble Creek provides a close and convenient place to stay along with a breath taking view of the upper Coffman valley. The Caamp is also very close to Chaumette and Charleville. If outdoor adventure is what you seek The Caamp serves as a great landing zone to explore nearby attractions like Pickle Springs and Hawn State Park. Sit back and enjoy the view from this gorgeous and cozy tiny home.
LocationValueParks
4.95 out of 5 average rating, 109 reviews
Cozy Country Home, just outside Farmington
Welcome to our cozy country house, perfect for families and friends! With 5 bedrooms, including 1 king bed, 3 queen beds, and 2 twin beds, it fits up to 10 people. Enjoy modern comforts in a charming country setting. Our 3-acre yard is great for play and relaxation, and we welcome dogs! Conveniently located, we're 10 minutes from Twin Oaks Winery, 9 minutes from Pickle Springs, and 2 miles from Farmington, MO. We also have a two-car garage and plenty of parking for guests.
FamilyLocationGrill
4.95 out of 5 average rating, 39 reviews
The Tiegen Rae: cozy mountain cabin w/ huge views
Take it easy at this unique and tranquil getaway. "The Tiegen" is a beautiful A-frame cabin sitting on 20 acres at the top of Anderson Mountain. Imagine drinking your morning coffee sitting in a rocking chair and enjoying the breathtaking view of the Mark Twain National Forest. Or picture lighting an evening fire to enjoy the sounds of the woods with your favorite drink. This cabin will not disappoint and boasts full amenities to go along with your glamping adventure.
FamilyLocationHiking
4.96 out of 5 average rating, 53 reviews
Train Caboose Getaway | Elephant Rocks + Firepit
Skip the ordinary and spend the night aboard an authentically restored 1958 train caboose—a destination all its own. Filled with vintage railroad artifacts and modern comforts, this unique Missouri stay brings its history to life. Sleep in a queen bed or cozy cupola loft, then relax by the firepit, play yard games or enjoy coffee on the platform. Close to Elephant Rocks and scenic outdoor adventures—a memorable Missouri getaway for couples, families and train lovers.
FamilyValueDecor
4.97 out of 5 average rating, 30 reviewsPopular amenities for Knob Lick vacation rentals
Other great vacation rentals in Knob Lick

Sweet Getaway
FamilyLocationComfort
4.95 out of 5 average rating, 80 reviews
The Hideaway 2
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4.98 out of 5 average rating, 57 reviews
Rosemary's Retreat -Serenity in town
LocationValueKitchen
5.0 out of 5 average rating, 46 reviews
Parsons Maple Leaf Cottage
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River Rose House | Retreat, Relax, Recharge
FamilyLocationCheckout
4.72 out of 5 average rating, 18 reviews
Bluebird Meadows **POOL AND HOT TUB**
ValueLocationHiking
4.96 out of 5 average rating, 75 reviews
248 Avalon Ranch Rd Cabin A
LocationFamilyIndoor spaces
4.99 out of 5 average rating, 77 reviews
Taylor Ave Retreat | Relax + Work w/ Firepit
LocationFamilyLong stay
4.93 out of 5 average rating, 14 reviewsDestinations to explore
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