Vacation rentals in Jackson

Guesthouse in Cape Girardeau

A gravel parking area is presented in the foreground, accommodating a vehicle. Lush green grass surrounds the parking space, while a fence and trees provide a natural backdrop. A garage is visible in the distance, partially obscured by greenery.

4.92 out of 5 average rating, 113 reviews

Cozy 1-BR guest house w/free parking on premises

Enjoy a cozy experience at this centrally, located place. Literally, a 1-4 minute walk to Mercy Hospital(formerly Southeast Hospital), less than 1 mile to Southeast University Campus, along with downtown(river). A street over is Broadway with many restaurants. Walmart Market and Dollar General are also conveniently located nearby. The kitchen is fully furnished with cooking utensils, clean towels, pots and pans for those who prefer eating in. Please no animals and no smoking in the apartment.

4.99 out of 5 average rating, 279 reviews

A warm-toned wood-paneled room features two sets of double doors, adding a rustic charm. A simple patterned bedspread covers a spacious bed, while a small wooden table is present beside it. The hardwood flooring complements the natural aesthetic.

Cabin in Alto Pass

Ma's Cabin, Alto Pass, IL. Fine country lodging.

Cute and country remodel done in 2019. Recent new appliances, furnishings, flooring, heat & A/C, washer & dryer. Cabin is secluded and quiet plus 1/2 mile from Alto Pass Lookout Point and right in the middle of many award-winning wineries. 15 miles from Carbondale 4 miles from Giant City 30 miles from Garden of the Gods 6 lakes within 10-mile radius Hundreds of miles of hiking trails in nearby Shawnee National Forest 6 miles from Bald Knob Cross Please, no dogs! No smoking in cabin!

A well-lit entryway features a wooden mirror above a small table, adorned with a gold-colored vase holding red flowers. A collection of magazines is neatly arranged beneath the vase. Soft, sheer curtains frame a window, allowing natural light to enhance the space.

4.98 out of 5 average rating, 416 reviews

Beautiful Historic Boulevard District Apartment

This beautiful, private upstairs apartment is located on a favorite street in Cape Girardeau’s Historic Boulevard District. It is walking distance to SEMO University, Capaha Park, and the downtown riverfront. Recently remodeled for laundry, spacious rooms offer private bedroom spaces and a cozy den for watching movies or reading. The kitchen is fully equipped with amenities. This quiet neighborhood setting even has a front porch swing and sitting area where you can enjoy your morning coffee.

A workspace is presented with a white desk and a contemporary black office chair. A softly glowing lamp adds illumination, while a window reveals a view of the private back deck. Natural light enhances the welcoming environment.

4.82 out of 5 average rating, 114 reviews

Herman’s Corner Cottage

Tucked in historic Cape Girardeau, this charming cottage offers comfort and convenience. Enjoy the cozy back deck with a privacy fence—perfect for relaxing or grilling. With ample off-street parking, your stay is stress-free. The home is equipped with essentials for a smooth, hassle-free visit. Book the entire house for added privacy, providing a peaceful retreat for you and your guests. Experience the perfect blend of comfort, affordability, and convenience during your Cape Girardeau getaway.

Guest suite in Cape Girardeau

A well-lit hallway features a round mirror above a dark dresser with a decorative tray and small plant. To the right, a door leads to another room, while wall hooks are visible for hanging items. A woven pendant light adds a soft glow.

4.97 out of 5 average rating, 151 reviews

MAINSTAY CAPE [downtown]

Nestled in the heart of the Downtown Historic District, this suite is centrally located as a prime destination for any and all travelers alike. With parking available, this space offers a unique & trendy “midwest boho” vibe. ~WALKABLE~ Our studio is 1 block from the bustling Southeast Missouri State University, 1 block from the gorgeous Capaha Park, and 2 blocks from Mercy Hospital. If you are interested in night life, this space is simply a 5-10 minute walk to all DT bars and restaurants.

A spacious deck features wooden flooring with a sleek surface, complemented by two black chairs. A circular white table sits between them, and a potted plant with vibrant flowers adds a touch of greenery to the space.

4.95 out of 5 average rating, 247 reviews

Brand new 2 bedroom unit right in downtown Cape.

This special place is close to everything, making it easy to plan your visit. Walking distance to restaurants, the river and nightlife. Property includes wifi, full kitchen, laundry, deck and private parking for one. One king bed room and a twin bed room in addition to a roll out twin bed along with a 60 inch smart television. Dog bed and bowls included along with board games! Property is conveniently located across the street from "The Bar" the famous spot from the movie "Gone Girl" .

4.86 out of 5 average rating, 610 reviews

Unique Design | Walk Downtown/River | .5 mile SEMO

At our Adventurous 2 Bedroom Suite you’ll first arrive at a Brightly decorated Space with Artsy Walls and Bold Decor. Designed with its History in mind & a twist of Creativity, you will Immerse Yourself within your Stay; from our Stocked Kitchen, Reading Area with Indoor Swing to Themed & Cozy Bedrooms. Enjoy being near Downtown/the River with a short Bike Ride or Walk and when you are ready to Tuck in at night, Sink into our 10” Memory Foam mattress with Plush Pillows and feel at Ease.

Treehouse in Cape Girardeau

A spacious deck offers a scenic view surrounded by trees, with glass railings enhancing the openness. Comfortable loungers provide a relaxing spot to take in the natural surroundings, while a BBQ grill is accessible for outdoor cooking.

4.99 out of 5 average rating, 142 reviews

Twisted Sassafras Treehouse

A custom-built treehouse located on 10 acres with a water view that you can take in from the hot tub on the deck! It is nestled high in the trees and is the perfect romantic getaway for two! Feel like you are away from it all without being away from it all! This treehouse is located on a county road just minutes from Cape Girardeau. Enjoy catch and release fishing on site, local wineries, shopping in historic downtown Cape Girardeau, local restaurants, gambling, historical sites & more!

The newly remodeled kitchen features white cabinetry and a spacious counter area. Stainless steel appliances, including a refrigerator and oven, are visible. Two tall bar stools are positioned at the counter, which is accompanied by natural light streaming through a nearby window.

4.85 out of 5 average rating, 124 reviews

5 Bed Home in Great Neighborhood - Sleeps 10

Looking for a comfortable and spacious Airbnb in Cape Girardeau? 🏡✨ This 3 bedroom, 2 bathroom home in a great neighborhood is the perfect spot for your next group stay. This home features great living areas to relax and unwind including a living room with a large sectional and 70 inch TV. The game room features an air hockey table, dart board, and other board games. It will sleep 10 comfortably. Make this your destination for your next girls trip, sports tournament, or SEMO event.

4.96 out of 5 average rating, 196 reviews

A cozy outdoor fire pit area is surrounded by five blue Adirondack chairs, set against a vibrant sunset sky. Warm lighting hangs overhead, illuminating the spacious yard and providing a welcoming atmosphere for evening gatherings.

Barn in Cape Girardeau

Under the Stars - Farmhouse

Enjoy the tranquility of this modern farmhouse charmer! Custom built minutes from downtown Cape. Relax outside around the fire pit, roast marshmallows and watch the sunset. Finish the night with a long soak in the hot tub. Start the morning on the front porch rocking chairs and take in a sunrise. Open concept, fully equipped kitchen, 3 Bd. including King master/full bath, 2 Queens with full guest bath. Near Trail of Tears and walking distance to classic dive bar/burger joint

Guesthouse in Cape Girardeau

A wall featuring a combination of rough brick and stone textures is displayed. A clear parking sign stating 'GUEST HOUSE PARKING ONLY' is prominently positioned against the wall, ensuring visibility for guests utilizing the designated parking area.

4.93 out of 5 average rating, 518 reviews

Downtown Guesthouse- Romantic Getaway

The guesthouse seamlessly blends modern amenities with historic charm in a cozy, compact space. The antique claw foot tub/shower combo offers a charming, yet snug, spot for a relaxing soak—true to its historic roots, the bathroom could be best described as a quaint water closet. After a day of exploring unwind in the patio. Play a favorite record, and savor your coffee while daydreaming about new experiences. Despite its small size, it provides all the modern comforts you need.

A hallway is depicted, showcasing a doorway leading to a cozy bedroom. The walls are adorned with teal paint, while a decorative mirror and artwork frame the entrance. The wooden floor reflects natural light coming from a window at the far end.

4.77 out of 5 average rating, 100 reviews

Historic Blvd District Home in Cape Girardeau

This beautiful, private home is located on a favorite street in Cape Girardeau’s Historic Boulevard District. It is walking distance to SEMO University, Capaha Park, and the downtown riverfront. With large bedrooms, spacious living room and separate dining room you will have all the room you need! The kitchen is fully equipped with amenities. This quiet neighborhood setting with a big front porch sitting area where you can enjoy your morning coffee.

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Other great vacation rentals in Jackson

5 out of 5 average rating, 96 reviews

A modern hot tub is positioned on a wooden deck, featuring illuminated water that reflects a soothing blue hue. Nearby, a dining area is displayed with a vibrant table and colorful chairs, framed by blooming flowers and the warm glow of the cabin's windows.

Cabin in Pomona

Modern Cabin at Trillium Ridge

RobRating, 5 stars4 days ago

My wife and i were here for a short getaway. Wanted a private and quiet place and Phillip’s cabin is just that! Enjoyed the outdoors and peaceful surroundings they developed on this property. Cabin was great. A ton of attention to detail when this place was built. All around perfect quick getaway for my wife and i. Definitely recommend Phillip’s cabin if you want to get away from the day to day life and unplug.

Guesthouse in Cape Girardeau

Two children are observed watching a large paddleboat moored along a riverbank. The boat features multiple decks, with an American flag prominently displayed. A rocky shoreline is visible in the foreground, under a clear blue sky dotted with clouds.

5 out of 5 average rating, 96 reviews

Private two room suite in downtown Cape Girardeau

AnnRating, 5 stars1 day ago

The rooms are really spacious and comfortable. Tom is terrific about letting us know what’s happening as well

The exterior of the home features a single-story structure with a neutral-colored façade and a welcoming front porch. A large window provides ample natural light, while neatly trimmed shrubs and greenery frame the entrance. A curved walkway leads to the front door.

4.9 out of 5 average rating, 10 reviews

Cape Charm: 3 BR Close to SEMO & Mercy! CLEAN!

StephanieRating, 5 stars2 weeks ago

Great stay, beautiful home. Only feedback would be to add another tv in one of the other bedrooms. 3 bedroom house and only one of the bedrooms has a tv.

4.77 out of 5 average rating, 13 reviews

The kitchen is equipped with modern appliances, including a refrigerator, stove, and microwave. Light wood cabinets and counters create a clean look, while a checkered rug adds a touch of warmth. A ceiling fan enhances airflow, and decorative accents are present on the countertops.

Home in Jackson

Rural Comfort in Fruitland

StanislauRating, 5 stars1 week ago

We had a great stay! The place was clean, comfortable, and exactly as described. It was very quiet, which we really appreciated. The host was responsive and helpful, and the check-in process was smooth. Would definitely stay here again!

4.96 out of 5 average rating, 23 reviews

Walnut Haven (formerly Rose Hill Cottage)

ChristinaRating, 5 stars1 week ago

Stayed for the Freedom Fest in Cape and had a great time!

The kitchen features wood cabinetry and a decorative light fixture, casting a warm glow. A window with patterned valance allows natural light to illuminate the space. A small table with two high-backed chairs and a fruit bowl offers a cozy dining area. The floor is covered with patterned tiles.

4.92 out of 5 average rating, 12 reviews

Colorful Home in Cape

ChrisRating, 5 stars1 week ago

Conveniently located close to many restaurants and attractions. Well worth the cost to stay there.

4.96 out of 5 average rating, 47 reviews

A compact kitchen area is equipped with countertop space and a sink. Shelves hold dishes, mugs, and glassware, while a coffee maker is positioned near clean dishes drying in a rack. A microwave is mounted above the counter, surrounded by light-colored cabinetry.

Apartment in Carbondale

Regal Rustic Retreat

AmandaRating, 5 stars1 week ago

Perfect peaceful place to stay while we did some hiking and then wine trails. Everything was as described and all drawers and light switches were labeled which was really nice.