Guesthouse vacation rentals in Frederick County
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Top-rated guesthouse rentals in Frederick County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Frederick County guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Frederick
4.97 out of 5 average rating, 316 reviewsThe Shady Bear Cabin
Feb 15 – 22
Guesthouse in Middletown
4.95 out of 5 average rating, 246 reviewsIndulge, Fresh Flowers, Frederick County Haven
Sep 21 – 28
Guesthouse in Smithsburg
4.97 out of 5 average rating, 645 reviewsJewel Vinsota Artist's Guesthouse
Aug 30 – Sep 6
Guesthouse in Frederick
4.98 out of 5 average rating, 160 reviewsPool and Heated Spa Open April 1st
Dec 15 – 22
Guesthouse in Frederick
4.86 out of 5 average rating, 29 reviewsThe Wander Inn
Dec 30 – Jan 6
Guest house rentals with a patio
Guesthouse in Middletown
Simple gestures
Nov 24 – Dec 1
Guesthouse in Boonsboro
New place to staySRV Room @Music House. Please Read Half Bath only
Jan 17 – 24
Guesthouse in Lovettsville
4.94 out of 5 average rating, 122 reviewsThe Patent House
Dec 27 – Jan 3
Guesthouse in Myersville
4.93 out of 5 average rating, 192 reviewsSpruce Run Cottage, Farm stay on Catoctin Mountain
Jun 18 – 25
Guesthouse in Mount Airy
4.99 out of 5 average rating, 77 reviewsTreasured Hideaway on the Hill
Sep 24 – Oct 1
Guesthouse in Middletown
5.0 out of 5 average rating, 92 reviewsCottage, Pool, & Breakfast on 100ac Horse Estate
Jul 23 – 28
Guest house rentals with a washer and dryer
Guesthouse in Myersville
4.93 out of 5 average rating, 192 reviewsSpruce Run Cottage, Farm stay on Catoctin Mountain
Jun 18 – 25
Guesthouse in Middletown
4.95 out of 5 average rating, 246 reviewsIndulge, Fresh Flowers, Frederick County Haven
Sep 21 – 28
Guesthouse in Smithsburg
4.97 out of 5 average rating, 645 reviewsJewel Vinsota Artist's Guesthouse
Aug 30 – Sep 6
Guesthouse in Frederick
4.98 out of 5 average rating, 160 reviewsPool and Heated Spa Open April 1st
Dec 15 – 22
Guesthouse in Frederick
5.0 out of 5 average rating, 234 reviewsThe Carriage House at Hessian Overlook, Downtown
Oct 6 – 13
Guesthouse in Frederick
4.86 out of 5 average rating, 29 reviewsThe Wander Inn
Dec 30 – Jan 6
Guesthouse in Frederick
5.0 out of 5 average rating, 77 reviewsA Quiet Haven
Oct 10 – 17
Guesthouse in Keymar
4.97 out of 5 average rating, 38 reviewsHistoric country guesthouse, newly renovated.
Feb 7 – 14
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