
Pet-friendly vacation rentals in Florence County
Find and book unique pet-friendly homes on Airbnb
Top-rated pet-friendly home rentals in Florence County
Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

Kuker Cottage Downtown Florence-Near I95 & I20
Kuker Cottage is a beautifully restored Florence home in the heart of downtown. Perfectly situated halfway between New York and Florida, it is an ideal overnight stopping point. Plenty of space to spread out, offering families room to unwind after a long day of traveling. This home has been beautifully updated and is ready to host you, whether for a short or an extended stay. 2 queen beds, one twin bed, full bath, kitchen, wifi and TV. Walkable to parks and restaurants. 4 miles from I95 and I20

Blu Grace Farm Apartment
Our barndo is located on our quaint 10 acre farm. The barn sits in the center of two pastures overseeing highland cows, horses, alpaca, donkeys, sheep and ducks. A cup of coffee, the sound of the rooster crowing while rocking under the awning is an experience in itself. Pet and feed the livestock during your visit. We are conveniently located near several wedding venues in historic Marion county and just an hour from Myrtle Beach. This is a rustic and peaceful farm experience you won’t forget.

*Cottage Near Florence and I-95* 3 Bedrooms
Located just 5 mins from I-95 and 12 minutes from Florence, this quaint cottage sits on 6 acres with private deck, firepit & large back yard in a peaceful, country location. Your pets are welcome (max of 2, pls) but are not allowed on our beds. 🧺. King bed in master, 3 TV's (two 55” & one 32”), coffee bar with Keurig, strong WiFi. We also use 100% cotton sheets and quilts for your maximum sleeping comfort. Absolutely no smoking ON OUR PROPERTY ($200 extra fee). Come stay with us!! 😊

Sleeps on the Creek!
Natures paradise! If you feel the need to get away from it all or are looking for accommodations that provide more than just a place to rest your head, this is the perfect getaway for you! Situated on the banks of Black Creek, this amazing property has all the amenities you need to remove you from the hustle and bustle while maintaining the conveniences of comfortable living and an ideal location. This 2 bedroom + loft, 1 bathroom home has everything you need to enjoy a stress-free getaway.

Gated and Private Catholic Hermitage house
Saint Michael Hermitage and retreat is a serene, gated, private home that is for 1-3 guests looking for a quiet stay while traveling or as a retreat destination. You will self check into your Hermitage after you obtain a gate code. There is a prayer chapel close by on the property. It is pet friendly for a well trained pet. There is Catholic iconography throughout the home. It is warm and inviting. There is a full kitchen, washer/dryer for your convenience and complementary coffee/tea.

Charming Home in Florence, SC
Welcome to Florence, South Carolina! This inviting 3-bedroom, 2-bathroom home is a haven of comfort and convenience. With four queen beds, it comfortably accommodates a group of friends or family. Step into the fully stocked kitchen, relax in the cozy living space, equipped with smart TVs for entertainment. The fenced backyard offers both privacy and a secure play area for your furry friends. Enjoy outdoor gatherings at the picnic table. Convenient amenities include a washer and dryer.

The Cottage at Dream Acres & Petting Zoo I-95/I-20
The Cottage at Dream Acres is situated with its own private drive on our 8 acre working horse farm located near Florence SC at the I-20/ I-95 corridor, 5 mins off the highway. We are the 1/2 way point between NY & FL. Relax and unwind from a long roadtrip or take a weekend farm-stay getaway. All the amenities of a larger home with the convenience of a smaller space! Family Friendly; sleeps up to 4, newly renovated in 2020, petting zoo, outdoor fire pit, tree swing, picnic table!

Boho Private Downtown Stay Near I-95 & Hospital
Comfort, cleanliness, privacy, and personality! Perfect for overnight stays or longer terms. Come enjoy our Boho hideaway in the heart of Florence. Our place has all the amenities of a hotel with the comfort and privacy of your own home including covered parking for two vehicles. We are located within walking distance to downtown Florence and a 5 minute drive to all of the restaurants and shopping that Florence has to offer. Come stay at our guest house and make yourself at home!

Governor's Square at Coventry @ I-20/I-95
This private, cozy two bedroom 1 1⁄2 bath condo has recently been renovated and is discounted for longer stays. The condo includes 2 bedrooms. It's located among quiet neighborhoods for peaceful walks or for sitting outside on the private patio. Within five minutes you’ll find access to I-20 & I-95, restaurants, malls, civic center, movie theater, Florence rail trail and parks, golfing, tennis, soccer and more. Highway 76 is two miles away and takes you directly to Myrtle Beach.

Quiet farmhouse near the beach
The best memories are made on the farm. Life is just better away from the hustle and bustle of city lights and busy schedules. Come stay in this recently renovated fourth generation 1950s farmhouse on an 80 acre working farm. Unwind on the porch, walk trails, find millions of years old sharks teeth, build a bonfire, pick blackberries, swim in the ponds, collect walnuts, or just relax while you’re here but don’t forget to wish on a dandelion or a shooting star before you leave.

Pickle in the Park - 1 Bedroom Studio Apartment
Come stay and play pickle ball at the courts in beautiful Timrod Park located in the heart of Florence or just keep it simple at this peaceful and centrally-located private 1 bedroom studio apartment. You’ll have plenty of parking with a spacious outdoor area. Everything you need is conveniently located within walking distance to the local Piggly Wiggly grocery store, library and award winning Historic Downtown. We look forward to welcoming you.

Cottage by the Pool: Close to Interstates
Palm Trees, colorful flowers, hammocks and quiet space await in this tropic-like oasis just minutes from I-95/20. Hundreds of reviews acknowledge this idyllic setting. We are a Florence Airbnb favorite for travelers. We offer a queen bed, full bathroom, full sleeper sofa, strong wifi and TV. We even provide breakfast bars and coffee to help you jump start your day as you set off for the next journey. We look forward to hosting you.
Popular amenities for Florence County pet-friendly home rentals
Pet-friendly house rentals

Collins Quarters

Crystal Place Near MUSC and Mcleod Hospital

Quiet, Clean & Spacious 4bd near I-95 & Hospital

Charming and spacious 4-bd 2 full ba WiFi, AC

Cozy One Story Town House

Spacious, Historic Home for 12 - Near Myrtle Beach

Bungalow near downtown & parks

Newly Renovated/Near Hospitals
Private, pet-friendly home rentals

2b/1.5bath brand NEW townhouse Closed to MUSC

Kuker Carriage House-Sleeps 3-Downtown/Near I95&20

Woody Crest two-bedroom home with free parking

Newly Remodeled 2 bed house

Spacious Stay for Crews | 4BR + Parking + WiFi

Crystal Green House

2B/1.5BA townhouse in florence

Creekside Cottage - 4 Bedrooms
Destinations to explore
- Hotel rentals Florence County
- Rentals with a washer and dryer Florence County
- Apartment rentals Florence County
- Rentals with outdoor seating Florence County
- Rentals with a fire pit Florence County
- Rentals with a fireplace Florence County
- Pet-friendly rentals South Carolina
- Pet-friendly rentals United States
- Myrtle Beach Boardwalk
- Family Kingdom Amusement Park
- Huntington Beach State Park
- Love's a Beach
- Myrtle Beach SkyWheel
- Garden City Beach
- Ripley's Aquarium of Myrtle Beach
- Arrowhead Country Club
- Myrtle Beach National
- Caledonia Golf & Fish Club
- Myrtle Waves Water Park
- Myrtle Beach State Park
- The Pavilion Park
- Dragon's Lair Fantasy Golf
- Deephead Swash
- WonderWorks Myrtle Beach
- Litchfield Beach and Golf Resort
- Tupelo Bay Golf Center
- Whispering Pines Golf Course
- Broken Groin
- Pawley's Island parking lot South
- Shipyard Village Building A - Litchfield By The Sea
- Litchfield Country Club
- Hollywood Wax Museum