Pet-friendly vacation rentals in Florence County

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in Florence County

Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

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Superhost
Home in Florence
4.87 out of 5 average rating, 532 reviews

Kuker Cottage Downtown Florence-Near I95 & I20

Kuker Cottage is a beautifully restored Florence home in the heart of downtown. Perfectly situated halfway between New York and Florida, it is an ideal overnight stopping point. Plenty of space to spread out, offering families room to unwind after a long day of traveling. This home has been beautifully updated and is ready to host you, whether for a short or an extended stay. 2 queen beds, one twin bed, full bath, kitchen, wifi and TV. Walkable to parks and restaurants. 4 miles from I95 and I20

Top guest favorite
Barn in Marion
4.98 out of 5 average rating, 197 reviews

Blu Grace Farm Apartment

Our barndo is located on our quaint 10 acre farm. The barn sits in the center of two pastures overseeing highland cows, horses, alpaca, donkeys, sheep and ducks. A cup of coffee, the sound of the rooster crowing while rocking under the awning is an experience in itself. Pet and feed the livestock during your visit. We are conveniently located near several wedding venues in historic Marion county and just an hour from Myrtle Beach. This is a rustic and peaceful farm experience you won’t forget.

Top guest favorite
Cottage in Timmonsville
4.97 out of 5 average rating, 991 reviews

*Cottage Near Florence and I-95* 3 Bedrooms

Located just 5 mins from I-95 and 12 minutes from Florence, this quaint cottage sits on 6 acres with private deck, firepit & large back yard in a peaceful, country location. Your pets are welcome (max of 2, pls) but are not allowed on our beds. 🧺. King bed in master, 3 TV's (two 55” & one 32”), coffee bar with Keurig, strong WiFi. We also use 100% cotton sheets and quilts for your maximum sleeping comfort. Absolutely no smoking ON OUR PROPERTY ($200 extra fee). Come stay with us!! 😊

Top guest favorite
Home in Florence
4.97 out of 5 average rating, 69 reviews

Sleeps on the Creek!

Natures paradise! If you feel the need to get away from it all or are looking for accommodations that provide more than just a place to rest your head, this is the perfect getaway for you! Situated on the banks of Black Creek, this amazing property has all the amenities you need to remove you from the hustle and bustle while maintaining the conveniences of comfortable living and an ideal location. This 2 bedroom + loft, 1 bathroom home has everything you need to enjoy a stress-free getaway.

Top guest favorite
Place to stay in Effingham
4.97 out of 5 average rating, 147 reviews

Gated and Private Catholic Hermitage house

Saint Michael Hermitage and retreat is a serene, gated, private home that is for 1-3 guests looking for a quiet stay while traveling or as a retreat destination. You will self check into your Hermitage after you obtain a gate code. There is a prayer chapel close by on the property. It is pet friendly for a well trained pet. There is Catholic iconography throughout the home. It is warm and inviting. There is a full kitchen, washer/dryer for your convenience and complementary coffee/tea.

Top guest favorite
Home in Florence
4.94 out of 5 average rating, 100 reviews

Charming Home in Florence, SC

Welcome to Florence, South Carolina! This inviting 3-bedroom, 2-bathroom home is a haven of comfort and convenience. With four queen beds, it comfortably accommodates a group of friends or family. Step into the fully stocked kitchen, relax in the cozy living space, equipped with smart TVs for entertainment. The fenced backyard offers both privacy and a secure play area for your furry friends. Enjoy outdoor gatherings at the picnic table. Convenient amenities include a washer and dryer.

Top guest favorite
Farm stay in Timmonsville
4.95 out of 5 average rating, 678 reviews

The Cottage at Dream Acres & Petting Zoo I-95/I-20

The Cottage at Dream Acres is situated with its own private drive on our 8 acre working horse farm located near Florence SC at the I-20/ I-95 corridor, 5 mins off the highway. We are the 1/2 way point between NY & FL. Relax and unwind from a long roadtrip or take a weekend farm-stay getaway. All the amenities of a larger home with the convenience of a smaller space! Family Friendly; sleeps up to 4, newly renovated in 2020, petting zoo, outdoor fire pit, tree swing, picnic table!

Top guest favorite
Guesthouse in Florence
4.98 out of 5 average rating, 855 reviews

Boho Private Downtown Stay Near I-95 & Hospital

Comfort, cleanliness, privacy, and personality! Perfect for overnight stays or longer terms. Come enjoy our Boho hideaway in the heart of Florence. Our place has all the amenities of a hotel with the comfort and privacy of your own home including covered parking for two vehicles. We are located within walking distance to downtown Florence and a 5 minute drive to all of the restaurants and shopping that Florence has to offer. Come stay at our guest house and make yourself at home!

Guest favorite
Condo in Florence
4.98 out of 5 average rating, 56 reviews

Governor's Square at Coventry @ I-20/I-95

This private, cozy two bedroom 1 1⁄2 bath condo has recently been renovated and is discounted for longer stays. The condo includes 2 bedrooms. It's located among quiet neighborhoods for peaceful walks or for sitting outside on the private patio. Within five minutes you’ll find access to I-20 & I-95, restaurants, malls, civic center, movie theater, Florence rail trail and parks, golfing, tennis, soccer and more. Highway 76 is two miles away and takes you directly to Myrtle Beach.

Top guest favorite
Farm stay in Hemingway
4.96 out of 5 average rating, 213 reviews

Quiet farmhouse near the beach

The best memories are made on the farm. Life is just better away from the hustle and bustle of city lights and busy schedules. Come stay in this recently renovated fourth generation 1950s farmhouse on an 80 acre working farm. Unwind on the porch, walk trails, find millions of years old sharks teeth, build a bonfire, pick blackberries, swim in the ponds, collect walnuts, or just relax while you’re here but don’t forget to wish on a dandelion or a shooting star before you leave.

Guest favorite
Apartment in Florence
5 out of 5 average rating, 9 reviews

Pickle in the Park - 1 Bedroom Studio Apartment

Come stay and play pickle ball at the courts in beautiful Timrod Park located in the heart of Florence or just keep it simple at this peaceful and centrally-located private 1 bedroom studio apartment. You’ll have plenty of parking with a spacious outdoor area. Everything you need is conveniently located within walking distance to the local Piggly Wiggly grocery store, library and award winning Historic Downtown. We look forward to welcoming you.

Top guest favorite
Guesthouse in Florence
4.93 out of 5 average rating, 875 reviews

Cottage by the Pool: Close to Interstates

Palm Trees, colorful flowers, hammocks and quiet space await in this tropic-like oasis just minutes from I-95/20. Hundreds of reviews acknowledge this idyllic setting. We are a Florence Airbnb favorite for travelers. We offer a queen bed, full bathroom, full sleeper sofa, strong wifi and TV. We even provide breakfast bars and coffee to help you jump start your day as you set off for the next journey. We look forward to hosting you.

Popular amenities for Florence County pet-friendly home rentals