Villa vacation rentals in Eastern Antioquia

Find and book unique villas on Airbnb

Top-rated villa rentals in Eastern Antioquia

Guests agree: these villas are highly rated for location, cleanliness, and more.

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Guest favorite

Villa in El Peñol

4.88 out of 5 average rating, 16 reviews

AquaVilla Crystal Spring Guatape

Strategic Lakeside location in LA CRISTALINA, “in between Peñol & Guatape” our modern villa is near everything. Restaurants, convenient stores, local market & tourist sites “A NATURAL PARADISE” Native forest & birds, our NATURAL SPRING FRESHWATER POOL, HOT JACUZZI, HOT TUB, deck & fancy linens make it a very comfortable & cozy convenient place Fully equipped, CHEF’S KITCHEN, DISHWASHER, high quality appliances, garage, 5TVs, WiFi, Directv, NETFLIX & all services available all in a unique place

Feb 6 – 13

R7,880 ZAR per night

Guest favorite

Villa in El Peñol

5.0 out of 5 average rating, 31 reviews

All-Inclusive Lakefront Villa & Movie Theater

Welcome to Villa Camila, our elegant lakefront villa in an exclusive, private gated community. Enjoy stunning panoramic views and a fully inclusive stay with a butler, private chef, housekeeping, dining experiences, complimentary groceries, and a selection of liquors. This expansive 5,400 sq. ft. retreat features 4 bedrooms, 5 bathrooms, a private movie theater, game room, sports field, and a beach-style swimming pool, perfectly accommodating 8 guests for a truly hands-free and relaxing getaway.

Sep 8 – 15

R17,174 ZAR per night

Superhost

Villa in El Peñol

5.0 out of 5 average rating, 8 reviews

Legacy Colombia: Modern Waterfront Luxury + Tennis

This huge Lake house in the countryside has everything you need for a luxurious and comfortable stay, an open and spacious living area with indoor fireplaces. Several places to relax with nature, outdoor furniture next to the BBQ and outdoor kitchen while watching the sunset. The jacuzzi is the perfect area for relaxing night. The chef’s kitchen is fully equipped with large oven, microwave, and a spacious dining/bar area where no one will be left out. Enjoy the private tennis court and kayaking!

Dec 5 – 12

R11,246 ZAR per night

Guest favorite

Villa in Medellín

4.98 out of 5 average rating, 62 reviews

The Las Palmas Mansion in El Poblado, Medellin

The Las Palmas Mansion (LPM) in El Poblado, Medellin is right out of an architectural magazine. It is stylish, modern, and professionally designed for a luxurious experience that is second to none. The LPM is very centrally located near restaurants, La Isla, Parque Lleras, Provenza, etc. The Mansion consists of 8 Bedrooms, 10 Bathrooms, beautiful heated Swimming Pool, Jacuzzi, Pool Table, & more. High Speed Wifi and A/C. Plus, we provide world-class service in Medellin, Cali, & Cartagena.

Jan 13 – 20

R20,436 ZAR per night

Guest favorite

Villa in Rionegro

5.0 out of 5 average rating, 51 reviews

Sweet Helen Llanogarden

Sweet Helen Llanogarden situado en el Tablazo-Llanogrande, a tan solo 10 minutos del aeropuerto internacional José Maria Córdova de Rionegro Antioquia, cerca a restaurantes, centros de eventos y malls, en el cual ofrecemos servicios de alojamiento para familias, amigos, parejas y viajes de negocios. En Sweet Helen Llanogarden encontrarás el espacio para pasar una estancia segura, tranquila y divertida, esta vez, rodeada de naturaleza y confort en la zona más exclusiva del oriente antioqueño.

Dec 21 – 28

R7,507 ZAR per night

Guest favorite

Villa in Medellín

5.0 out of 5 average rating, 11 reviews

Poblado Villa: Great views/Nature/Jacuzzi/Security

Welcome to our exquisite villa, a luxurious gated retreat nestled in the heart of El Poblado, Medellín's most sought-after neighborhood. Just a 5-minute journey from the vibrant area of Provenza. Experience privacy, comfort, and convenience in one of Medellín's premier properties. Our villa is not just a place to stay, but a destination in itself. Unique to us is our hospitality staff that is available 24/7 for any of your needs. Inquire about the additional services we offer.

Dec 31 – Jan 7

R17,212 ZAR per night

Guest favorite

Villa in Peñol

4.91 out of 5 average rating, 134 reviews

Bethania, Scenic rural house with impressive views

Confortable and unique rustic house on the top of a hill in Guatapé. With breathtaking views towards the lake and the impressive "Peñon de Guatapé" this is a great place to relax and enjoy the simple pleasures of life such as relaxing on a hammock, stargazing at night or enjoying a fire. The property offers many social areas including an external saloon with separate bathroom, billiard table and a hot tub from where you can enjoy a very scenic landscape.

Nov 10 – 17

R3,397 ZAR per night

Guest favorite

Villa in Medellín

4.92 out of 5 average rating, 103 reviews

Colonial Villa in Laureles, Unique&Special House

A Colonial House in the heart of Laureles; a typical and safe neighborhood in Medellin, named by time out as the coolest neighborhood in 2024. Walking distance to supermarket, bars and restaurants. The house has a huge living area where patios, living room, kitchen and nature are connected. It has been completely renovated in June 2019. You will feel to be in another era. It's a perfect house to be with your family or a group of friends

Jun 25 – Jul 2

R4,065 ZAR per night

Guest favorite

Villa in Támesis

4.97 out of 5 average rating, 36 reviews

Casa de Campo Natural setting with the best pool

Enjoy nature, tranquility and rest with the most spectacular landscape in the background. Beautiful cottage with the best pool, jacuzzi with whirlpool, relaxation waterfall, air bed. Spacious and comfortable rooms, beach for sunbathing, children's area. Turkish bath for 6. Eco hikes and fishing option in beautiful Rio Cartama. During your stay in the value include the person who helps you with the cleaning and the realization of the food.

Aug 17 – 24

R7,346 ZAR per night

Guest favorite

Villa in Medellín

5.0 out of 5 average rating, 27 reviews

Amazing Villa with stunning view & jacuzzi

Experience a slice of paradise in Medellín's upscale & verdant gated community. Our property, adjacent to a natural park, boasts stunning, unparalleled views of the cityscape and a vast nature reserve . Conveniently located just 20 minutes from vibrant nightlife n( lleras park) and 30 minutes from the airport, this serene haven offers the perfect blend of city access and tranquil retreat, enveloped in fresh & pure air.

Nov 7 – 14

R13,555 ZAR per night

Guest favorite

Villa in Rionegro

5.0 out of 5 average rating, 43 reviews

Spectacular farm house in Llanogrande : Zaragoza

Beautiful finca house in Llanogrande with capacity for up to 16 people, all amenities, spacious rooms, jacuzzi, green area, children's games and everything you need for a spectacular stay with friends. Close to Rionegro, La Ceja, El Retiro, Guatapé, El Carmen and all the towns of the East Antioqueño, in addition to being only 40 minutes from Medellin. Come and connect with nature in this unforgettable getaway.

Jul 28 – Aug 4

R6,181 ZAR per night

Guest favorite

Villa in Medellín

4.82 out of 5 average rating, 190 reviews

Rest and tranquility in El Poblado

Beautiful house in the heart of Poblado, Castropol sector. With spectacular pool surrounded by trees and gardens. Completely renovated house with all the amenities so that you feel comfortable with your partner, family and/or friends. Just 5 min walk from Poblado Park, 3 min from Manila neighborhood, easy access to shopping centers, Provence neighborhood and Lleras Park. we have RNT 92280

Oct 15 – 22

R8,888 ZAR per night