
House vacation rentals in DeSoto County
Find and book unique houses on Airbnb
Top-rated house rentals in DeSoto County
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for DeSoto County house rentals
House rentals with a pool

Seasonal vacation rental with Heated pool

Green Bamboo - saltwater pool, great backyard.

PORT CHARLOTTE FLORIDA RETREAT, 2/2, PRIVATE POOL

Fun Luxury Stay: Mini Golf, Heated Pool, Bowling

Heated Pool Vacation Getaway

Flourish in Florida heated pool & spa

Cozy & Beautiful Pool Villa in Sarasota County, FL

Amazing Peace River Views
Weekly house rentals

Country Villa w/patio and huge yard for parking

Sunshine Acres

Farm Cottage in Arcadia

Guest House

Sly Gator House

Hernando House 3/2 w private backyard and patio

An updated unique 3 bedroom 1 bathroom home rental

Brand new home 3/2 large patio, Citrus home
Private house rentals

Country Villa w/patio and huge yard for parking

Sunshine Acres

Farm Cottage in Arcadia

Guest House

Sly Gator House

Hernando House 3/2 w private backyard and patio

An updated unique 3 bedroom 1 bathroom home rental

Brand new home 3/2 large patio, Citrus home
Destinations to explore
- Siesta Beach
- Crescent Beach
- Turtle Beach
- Caspersen Beach
- Lido Key Beach
- Streamsong Resort
- Manasota Key Beach
- River Strand Golf and Country Club
- Point Of Rocks
- Englewood Beach
- Marie Selby Botanical Gardens
- Lakewood National Golf Club
- North Jetty Beach
- Stump Pass Beach State Park
- Blind Pass Beach
- South Jetty Beach
- Gasparilla Island State Park
- Myakka River State Park
- Boca Grande Pass
- Tara Golf & Country Club
- Del Tura Golf & Country Club
- Manatee Park
- Legacy Golf Club at Lakewood Ranch
- Crescent Beach, Sarasota