Vacation home rentals in South America

Find and book unique vacation home rentals on Airbnb

Top-rated vacation home rentals in South America

Guests agree: these vacation home rentals are highly rated for location, cleanliness, and more.

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Guest favorite

The exterior showcases a modern two-story building featuring a mix of dark siding and natural stone accents. Sturdy stairs lead to the upper entrance, while large windows on both levels provide ample natural light. A serene landscape of hills is visible in the background.

Vacation home in El Chaltén

4.9 out of 5 average rating, 140 reviews

House 3, BUENAVISTA CHALTEN, MOUNTAIN HOUSES.

Brand new, high quality apartment. 2 bedrooms, fully equipped and 50 square meters. Living room, dining room, and full kitchen with quality supplies and appliances (refrigerator, toaster, stove with oven, microwave, electric kettle, etc.) and 2 giant windows in the kitchen and living room with one of the best views of the town. Each bedroom has a box spring and quality linens, with a choice of beds. 3 smart TVs, Wi-Fi, etc. Very good location, meters from the beginning of trails and close to downtown.

Top guest favorite

A bright living area features a spacious seating arrangement with a sofa bed and a unique wooden coffee table. A dining table for six is set beside large windows, allowing for ample natural light. Decorative wall art complements the neutral decor.

Vacation home in Ushuaia

4.95 out of 5 average rating, 139 reviews

CHUNCHU’S APARTMENT WONDERFUL VIEWS. NEAR DOWNTOWN

Excelente ubicación en edificio de categoría ( Amundsen) con 2 ascensores. A una cuadra de la avenida principal San Martin, cerca de supermercados, restaurantes, centros médicos, a 10 minutos del aeropuerto en auto. El departamento tiene excelentes vistas al canal de Beagle . Living comedor integrado a la cocina, cuarto principal con vestidor, baño completo. colchones, sabanas y toallas de calidad hotelera. Equipado para que duerman hasta 5 personas. Smart Tv, Tv 32. Para disfrutarlo a pleno!

Top guest favorite

A light-filled living area features a spacious sectional sofa arranged around a coffee table, accompanied by two round ottomans. Soft, neutral tones are present throughout, with wall art depicting serene beach scenes. The loft area is visible above, creating an open and airy feel.

Vacation home in CARTAGENA

4.98 out of 5 average rating, 129 reviews

Brand New 1 BR Luxury Suite/Loft Historic Center

1 BR Loft Suite in the heart of Cartagena inspired by some of the finest 5 star Hotels in the world. Located inside the walls of the old city, within walking distance to shops, entertainment, restaurants, nightclubs & bars. Enjoy staying in this Unesco Heritage town full of history & excitement. Fully equipped kitchen with Washer/Dryer, Queen Sized Bed, pullout Couch, TV, Netflix and 400MbWi-Fi. Our modern beach vibe apartment is perfect for a couple to enjoy and relax. Intagram @pombocartagena

Top guest favorite

A cozy living space features a comfortable daybed adorned with decorative pillows in natural tones. A green plant adds a touch of freshness, while wall decor made of organic materials enhances the serene ambiance. Light streams through a window, illuminating the inviting space.

Vacation home in Coco

4.95 out of 5 average rating, 197 reviews

Apart. King bed by casa aire near airport/beaches

Brand new spacious modern apartment by Casa Aire/ 25 minutes from LIR airport/private garden Casa Aire is a small compound, conformed for five accommodations with a unique modern and organic architecture. Creating a relaxed atmosphere ideal for restoring senses after a day of adventure on the bech or nearby national parks. 10 minutes walk from Main steet Coco beach downtown or beach. easy flat wlking areas. FREE ACCESS TO TWO PRIVATE CLUBS at the area. ideal for workations.

Guest favorite

A cozy corner showcases two accent chairs surrounding a small coffee table, with a soft rug underneath. Large windows allow natural light to flood the space, framing a serene view of the distant mountains and the warm hues of sunset.

Vacation home in São Bento do Sapucaí

4.97 out of 5 average rating, 174 reviews

Aconcágua Cottage

Reconnect with nature at SANTALENA REFUGE!! Newly inaugurated, our chalet is thematic and refers to the highest mountain in America, Aconcágua. Like Aconcágua and following the local constructions, this chalet is all solid stone, has a green grass roof and Andean architecture using rustic woods. The most beautiful sunset in the region!! A private and safe location. We are close to Pedra do Baú, Pedra do Baú restaurant and 25 minutes from the city of São Bento.

Superhost

A modern chalet is depicted with large glass doors opening to a stylish interior. An inviting pool reflects outdoor lighting, while a cozy outdoor seating area is centered near the water. Natural wood and warm tones create a serene ambiance.

Vacation home in Pirenópolis

4.95 out of 5 average rating, 278 reviews

Quinta dos Goyazes - Oka do Pequi Farm

Exclusivity, privacy, quiet in the midst of nature and lots of comfort. Ingredients that make Quinta dos Goyazes Eco Boutique a unique experience in Pirenópolis for those who love to escape the noise, explore nature in an eco boutique full of charm. To make better use of the experience, we recommend a two night minimum. Self-check-in from 3pm and self-checkout UNTIL 11am. In case of delay, a fine of 30% will be charged on the daily rate.

Guest favorite

A serene infinity pool is visible, reflecting the vibrant sunset over the ocean. Lush greenery surrounds the pool area, and a comfortable seating arrangement is positioned nearby, offering views of the horizon. The sky is adorned with clouds illuminated by warm daylight.

Vacation home in Quepos

4.89 out of 5 average rating, 153 reviews

Villa Calypso

This villa brings you the most spectacular sunset in all of Manuel Antonio. This private and secluded Villa, places you high into the clouds, overlooking the beautifully. Our personal concierge will take the worry out of your stay by planning all your needs. Once you book your reservation, your concierge will reach out to help you start planning the trip of your dreams. * No small kids *

Top guest favorite

A small swimming pool is positioned within a lush garden, surrounded by various tropical plants. Bright blue lounge chairs are situated next to the pool, creating a relaxing spot. Towering palm trees and dense greenery serve as a natural backdrop, enhancing the tranquil atmosphere.

Vacation home in Puerto Viejo de Talamanca

4.99 out of 5 average rating, 239 reviews

Quinta Guarumo #02

Relax on this unique and tranquil getaway in the middle of the Caribbean jungle and just a 5-minute drive from Cocles Beach. We offer a separate bungalow from where you can relax with a breathtaking view of the jungle and its wildlife. They will have the possibility to see toucans, large green limpets, oropendolas, sloths, etc. IMPORTANT: Read Other Aspects to Note.

Guest favorite

A single-story structure built with stone and adobe features a terracotta roof. Large wooden windows invite natural light, while a swimming pool stretches in the foreground. Scenic mountain views provide a relaxing backdrop, surrounded by garden space and a charming vine.

Vacation home in Cafayate

4.97 out of 5 average rating, 187 reviews

Romantic Apartment for 2

Relajate en este alojamiento único y tranquilo. Nuestros departamentos proveen confort y privacidad, con detalles calidos y terruños. Las vistas impresionantes de los cerros se pueden disfrutar desde la galeria. El espacio comun ofrece una pileta de natacion (habilitada durantes Oct-Abr) y el sol se puede disfrutar debajo de nuestras parras añejas de Torrontes.

Top guest favorite

A bright bedroom is showcased, featuring a spacious bed with a light blue coverlet and decorative pillows. An elegant headboard complements the bed. A television is positioned on a stand, displaying streaming options. Large windows offer natural light and city views, enhancing the atmosphere.

Vacation home in San Nicolás

4.95 out of 5 average rating, 154 reviews

Encantador Apart Obelisco

This special place is close to everything, making it easy to plan your visit. Located a few meters from the Obelisk, on Corrientes Avenue, "the one that never sleeps" Next to the Opera House, in front of the Gran Rex, 2 blocks from Obelisco, 8 blocks from Puerto Madero. An area with theaters, bars, and restaurants. Ideal location, which will facilitate your stay.

Guest favorite

A modern studio layout is presented, showcasing a comfortable seating area with a gray sofa. Behind it, a decorative wooden partition separates the sleeping space, which is illuminated by natural light from large windows. A dining area with stylish chairs and a small table is also visible.

Vacation home in AAD

4.89 out of 5 average rating, 179 reviews

Modern Apartment in the Heart of San Telmo

In the heart of San Telmo, a unique and ideal place to get to know this fantastic city and enjoy its culture and gastronomy. Fully equipped to make your stay unique. In the heart of San Telmo, you will find a unique and ideal place to get to know this fantastic city and enjoy its culture and cuisine. Fully equiped to make your stay unforgetable.

Top guest favorite

An outdoor terrace offers a panoramic view of the city skyline, framed by greenery. Comfortable outdoor seating is arranged around a wooden table, and the space is complemented by a partially covered roof that allows for relaxation while enjoying the scenic surroundings.

Vacation home in Bogotá

4.96 out of 5 average rating, 129 reviews

MAGNIFICENT APT IN LA CANDELARIA WITH 180º VIEW

Excellent location in the La Candelaria neighborhood, historic center of Bogota, loft-style space with 5-star finishes and amenities, terrace with 180º view. A safe area where you will find bars, restaurants, museum and representative places such as Monserrate Hill, Bolivar Square among others, without a doubt an unforgettable experience.