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Hotel vacation rentals in Santo Domingo De Guzmán

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Top-rated hotel rentals in Santo Domingo De Guzmán

Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.

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A spacious living area features a curved blue sofa paired with a bright yellow accent chair. A marble coffee table is centered on a soft area rug, with decorative plants and a modern light fixture enhancing the inviting design. Abstract art adorns the walls.
Hotel room in Ciudad Universitaria
4.77 out of 5 average rating, 112 reviews

Comfortable and well-equipped apartment near the pier

Apartamento super cómodo y elegante para acomodar a la familia o amistades, Nos encontramos a 5 min del Teatro Nacional, muy cerca de los Centro Comerciales mas visitados, clínicas y hospitales. Exactamente en el centro de Santo Domingo. 5 min del área Colonial, aledaño a restaurantes y bares. Este será el lugar de hospedaje ideal para ti y los tuyos, cuál sea la ocación, pasatiempo o vacaciones en la gran capital Dominicana, llegaste al lugar ideal...

Guest favorite
Private room in Ciudad Colonial
4.89 out of 5 average rating, 171 reviews

Casa Donderis Colonial - Double Room

The room is part of my colonial house, a space dedicated to travelers who want to explore the cultural side of Santo Domingo. It is important to note that this is not a hotel, so guests are expected to respect coexistence and maintain a clean and orderly environment. Currently, some of the rooms are occupied by young people temporarily working on projects in the country, so the atmosphere is familiar and quiet, with daytime hours being observed.

Guest favorite
A spacious room features a King bed with a soft blue coverlet and a neatly arranged yellow towel. A bedside table and lamp provide subtle illumination, while a large mirror enhances the room's openness. A small plant adds a touch of greenery, complementing the neutral color scheme.
Hotel room in Ciudad Colonial
4.91 out of 5 average rating, 11 reviews

Elegant Suite in the Old Town

Stay at Gato Colonial, a cozy hostel in Santo Domingo’s Zona Colonial. Suite 2-1 has a King Bed, private bathroom, A/C, hot water, desk, fast WiFi, smart TV, mini fridge & balcony. Perfect for digital nomads and travelers! Use the shared kitchen and enjoy amazing views of historic sites. Walk to top restaurants, shops & attractions. Experience the charm of the city—book your stay at Gato Colonial today!

A modern kitchen space is shown, featuring white cabinetry and a microwave above a gas stove. Two bar stools are positioned at an island counter. A stainless steel refrigerator stands against the wall, alongside a small garbage bin and a potted plant for subtle decoration.
Casa particular in Luperon
4.53 out of 5 average rating, 15 reviews

LJC Stay II

Este apartamento moderno y luminoso es el lugar perfecto para una escapada urbana. Con un diseño elegante y espacios bien distribuidos, ofrece un ambiente relajante y lleno de confort. Cada rincón ha sido pensado para brindarte una experiencia única, desde la cómoda cama en el dormitorio principal hasta la zona de estar con detalles decorativos que aportan calidez.

Superhost
The Hotel Conquistador is shown, featuring a multi-story building with a bright yellow exterior. An awning displays the hotel name prominently. Several parked cars are visible in front of the entrance, and a clear blue sky provides a contrasting backdrop.
Hotel room in La Julia
4.83 out of 5 average rating, 168 reviews

Hotel in downtown Santo Domingo

This stylish place is close to must-see destinations. A few meters from the financial center and the main shopping malls. At the same time, the university area and the pier are within walking distance. Fully renovated with special emphasis on details. Hotel Conquistador is a landmark in the city.

Superhost
A stylish bedroom features a large black bed with a quilted white coverlet. Beside it, a dark nightstand holds a small decorative plant. Soft lighting from wall fixtures highlights the textured walls. A plush rug rests under the bed, providing comfort and warmth to the space.
Hotel room in Ensanche Ozama
4.75 out of 5 average rating, 48 reviews

Standard 101

Vive la autentica experiencia en un alojamiento excepcional SOLMI ROOMS COFFE & DRINKS, estratégicamente ubicado para explorar lo mejor de Santo Domingo. A solo 25 minutos del aeropuerto, 10 minutos de la histórica Zona Colonial y a 5 minutos de una variada selección de restaurantes exclusivos.

Superhost
A spacious bedroom features a comfortable bed dressed with crisp white linens, flanked by two bedside lamps on matching nightstands. A seating area with a chair and a desk is visible, along with soft gray curtains that frame a window, enhancing the overall serene ambiance.
Hotel room in Bella Vista
5 out of 5 average rating, 3 reviews

Room with private bathroom

Room located in the center of Bella Vista, it is part of the facilities of a Hotel, with all the services and amenities it offers. You have access to all the common areas of the other guests such as the Gym, Restaurant and Rooftop with pool and disco. It has cable TV and WiFi.

A bright bedroom features a spacious bed with a patterned blue blanket. White linens and pillows create a clean look. Large windows with curtains let in natural light and provide views of the surroundings. Nightstands are positioned on either side of the bed.
Hotel room in Santo Domingo
4.77 out of 5 average rating, 64 reviews

Full apartment in the Gazcue area

It offers a bright and comfortable atmosphere in Italian style, designed to offer our guests the possibility of a short and long term stay in spacious one and two bedroom apartments, equipped with air conditioning, fully equipped kitchen and elegant decor.

Superhost
A spacious sleeping area features a large bed with a white quilt and teal accents. Two bedside tables with lamps flank the bed, and a light-toned dresser is positioned nearby. Natural light enters through a glass door, complemented by patterned tile flooring.
Hotel room in Ciudad Colonial
5 out of 5 average rating, 3 reviews

Brisas Colonial 103

Enjoy the simplicity of this quiet and central accommodation. On the historic Calle El Conde, with access to countless restaurants, museums, near the city's pier. Conducive to rest and sightseeing.

A modern living area with a white sectional sofa, accented by yellow and black decorative pillows. A tall vase filled with yellow flowers stands on a mirrored coffee table, reflecting the light. A patterned wall art piece adds visual interest above the sofa.
Casa particular in Los Restauradores
5 out of 5 average rating, 3 reviews

Casa Individual

Your family will be close to everything when you stay in this centrally located accommodation.

A light-filled room features a spacious bed with white bedding, complemented by two bedside tables with lamps. A private bathroom is visible in the background, equipped with a sink and a toilet, enclosed by a simple design.
Hostel in Gazcue
4.61 out of 5 average rating, 93 reviews

Las Carreras rooms

Single room with large common terrace in a very central area.

Guest favorite
Hotel room in Santo Domingo Este
5 out of 5 average rating, 7 reviews

Relax room with pool

You’ll love the stylish decor of this charming place to stay.

Popular amenities for Santo Domingo De Guzmán hotel rentals

Quick stats about hotel rentals in Santo Domingo De Guzmán

  • Total rentals

    310 properties

  • Nightly prices starting at

    R173 ZAR before taxes and fees

  • Total number of reviews

    3.7K reviews

  • Family-friendly rentals

    10 properties are a good fit for families

  • Pet-friendly rentals

    30 properties allow pets

  • Rentals with a pool

    60 properties have a pool

Destinations to explore