
Vacation rentals in Santa Isabel
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Santa Isabel
Guests agree: these stays are highly rated for location, cleanliness, and more.
0 of 0 items showing
1 of 3 pages
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Santa Isabel vacation rentals
Other great vacation rentals in Santa Isabel
Top guest favorite

Apartment in Ponce
4.99 out of 5 average rating, 67 reviewsD’Valley Apt.-Luxury/SOLAR-System/Priv-Pkg

Home in Santa Isabel
5 out of 5 average rating, 4 reviewsPretty house
Top guest favorite

Home in Salinas
4.94 out of 5 average rating, 35 reviewsCasa Gabriela in Salinas
Guest favorite

Home in Coamo
4.89 out of 5 average rating, 63 reviewsJaviMar Guest House with Pool & Solar Panels
Superhost

Apartment in Guayama
4.88 out of 5 average rating, 17 reviewsParadise at Legado Golf
Top guest favorite

Home in Santa Isabel PR
5 out of 5 average rating, 8 reviewsLas Casitas Beach Retreat
Guest favorite

Apartment in Piedra Aguza
4.89 out of 5 average rating, 45 reviews"Charming Oasis in Juana Díaz"
Top guest favorite

Home in Santa Isabel
5 out of 5 average rating, 6 reviewsLa Casita de Mami
Destinations to explore
- Punta Cana Vacation rentals
- San Juan Vacation rentals
- Santo Domingo De Guzmán Vacation rentals
- Las Terrenas Vacation rentals
- Santiago De Los Caballeros Vacation rentals
- Santo Domingo Este Vacation rentals
- Sosúa Vacation rentals
- Cabarete Vacation rentals
- La Romana Vacation rentals
- Bayahibe Vacation rentals
- Juan Dolio Vacation rentals
- Carolina Vacation rentals
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Distrito T-Mobile
- Playa Puerto Nuevo
- Peñón Brusi
- Toro Verde Adventure Park
- The Saint Regis Bahia Golf Course
- Playa Maunabo
- Coco Beach Golf Club
- Playa de los Cabes
- Playa Puerto Nuevo
- Playa de Cerro Gordo
- La Fortaleza
- Cerro Gordo National Park
- Playa Las Palmas
- Punta Guilarte Beach
- Cueva del Indio
- Balneario Condado
- Museo de Arte de Ponce
- Playa de Jauca
- Stream Thermal Bath
- Arecibo Observatory
- Los Tubos Surf Beach
- Panteon Nacional Roman Baldorioty de Castro
- Inches Beach
- Museo de Arte de Puerto Rico