Santa Fe River vacation rentals

Book unique cabins, vacation rentals, and more on Airbnb

Top-rated vacation rentals in Santa Fe River

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

Superhost

Cottage in Hawthorne

4.86 out of 5 average rating, 105 reviews

Live Oak Oasis on Morris Lake

Unspoiled nature greets your every turn at this charming 650 SF lakefront retreat. A short distance from 10 of Florida's finest 1st magnitude springs, ranging from 30 - 90 minute drive, makes the location a perfect basecamp for adventure travel. Rest beneath the shade of Live oaks that pull the breeze ashore. Enjoy Sand hill cranes and hummingbirds from the cabana. Incredible sunsets from new dock. Paddle boat & paddle boards available for adventures. WiFi, Netflix, Laundry, HOT outdoor shower!

Dec 3 – 10

R1,729 ZAR per night
Guest favorite

Guest suite in Gainesville

4.97 out of 5 average rating, 410 reviews

Private guest suite in a quiet modern farmhouse

This is an elegant and newly renovated private guest suite with its own separate entrance and private bathroom located in a 1950s single family residential home. Most of the furnishings are custom made! This is an ideal place to stay for visiting parents, traveling professional students, business travelers, general visitors to Gainesville, or anyone looking for a quiet place to stay. It is NOT a location to host parties, gatherings, or to hang out in groups. Please, NO SMOKING in our suite.

Oct 8 – 15

R1,400 ZAR per night
Guest favorite

Home in Earleton

4.97 out of 5 average rating, 176 reviews

Lake House Escape & Play

1950's remodeled home. Dock access is approx 500ft from house down to Big Lake Santa fe 7x3mi & up to 30ft deep. Perfect for skiing & fishing. Boat trailer between houses or along road. Use of dock & canoe free. The vacation venue next door, called "Boat House", has a boat ramp. It is $20 fee to launch boat or free ramp in Melrose, 3.5mi away. PLEASE be careful at dock. It is very sturdy but the hurricanes have washed out the sides. Grab 1 of the flashlights for a night walk to guide you.

Jun 17 – 24

R2,242 ZAR per night

Popular amenities for Santa Fe River vacation rentals

Santa Fe River cabins

Superhost

Cabin in Fort White

4.9 out of 5 average rating, 229 reviews

Cabin 3 Bowman's on Santa Fe River near Springs

Jan 8 – 15

R2,196 ZAR per night
Superhost

Cabin in Live Oak

4.78 out of 5 average rating, 234 reviews

Suwannee River Paradise

Sep 12 – 19

R2,170 ZAR per night
Guest favorite

Cabin in Micanopy

4.99 out of 5 average rating, 153 reviews

The Cabin at Shimmering Oaks

Aug 18 – 25

R2,962 ZAR per night
Guest favorite

Cabin in Live Oak

4.9 out of 5 average rating, 136 reviews

Riverbend Retreat Cabin on Suwanee River

Jul 28 – Aug 4

R2,956 ZAR per night
Guest favorite

Cabin in Dunnellon

4.95 out of 5 average rating, 149 reviews

Rustic River Home on the Withlacoochee River.

Dec 27 – Jan 3

R2,529 ZAR per night
Superhost

Cabin in Fort McCoy

4.85 out of 5 average rating, 175 reviews

Camp Fox Den. A waterfront A-frame with a view.

Dec 8 – 15

R1,542 ZAR per night
Guest favorite

Cabin in Fort McCoy

4.93 out of 5 average rating, 126 reviews

Reality Check / Salt Springs with a view

Sep 23 – 30

R2,747 ZAR per night
Superhost

Cabin in Fort White

4.79 out of 5 average rating, 116 reviews

Folkhouse at the Santa Fe & Ichetucknee

Jul 17 – 24

R3,438 ZAR per night
Guest favorite

Cabin in Live Oak

4.92 out of 5 average rating, 102 reviews

Florida Country Cabin Getaway

Jul 16 – 23

R5,647 ZAR per night
Guest favorite

Cabin in Ocklawaha

4.98 out of 5 average rating, 159 reviews

VERY BEARY CABIN on Crystal Lake

Sep 5 – 12

R4,271 ZAR per night
Guest favorite

Cabin in Dunnellon

4.86 out of 5 average rating, 215 reviews

Rainbow River getaway - kayaks, tubes & golf cart

Feb 14 – 21

R2,401 ZAR per night
Superhost

Cabin in Live Oak

4.87 out of 5 average rating, 107 reviews

RUSTIC CABIN OVERLOOKING HISTORIC SUWANNEE RIVER

Aug 21 – 28

R2,826 ZAR per night

Other great vacation rentals in Santa Fe River

Guest favorite

Home in Alachua

4.92 out of 5 average rating, 177 reviews

Peaceful Cottage in Alachua Florida

Aug 6 – 13

R1,808 ZAR per night
Guest favorite

Cottage in Melrose

4.91 out of 5 average rating, 145 reviews

Cozy Melrose Mermaid Cottage

Apr 9 – 16

R1,317 ZAR per night
Guest favorite

Tiny home in Alachua

4.87 out of 5 average rating, 165 reviews

Parvati Tiny Home ~ Outdoor claw foot tub

Sep 8 – 15

R1,993 ZAR per night
Guest favorite

Apartment in Melrose

4.88 out of 5 average rating, 164 reviews

The Orchid of Lake Santa Fe

Jan 9 – 16

R1,797 ZAR per night
Guest favorite

Home in Gainesville

4.81 out of 5 average rating, 109 reviews

El Ranchito

Mar 13 – 20

R1,922 ZAR per night
Guest favorite

Guesthouse in Gainesville

4.98 out of 5 average rating, 634 reviews

Unique Container "Caja Verde" 1 Mile UF & Downtown

Jun 15 – 22

R1,669 ZAR per night
Superhost

Farm stay in Lake Butler

4.8 out of 5 average rating, 307 reviews

The Tofu House at Moonrise Farm

Jun 16 – 23

R1,610 ZAR per night
Guest favorite

Tiny home in Fort White

4.96 out of 5 average rating, 351 reviews

Rum Island Cabin on Santa Fe River

Jan 22 – 29

R1,968 ZAR per night
Superhost

Guesthouse in Lake City

4.88 out of 5 average rating, 991 reviews

Studio loft/ kitchenette/porch/bath

Sep 9 – 16

R1,514 ZAR per night
Guest favorite

Home in Alachua

4.82 out of 5 average rating, 195 reviews

Gated Golf Getaway close to Springs

Jun 19 – 26

R2,671 ZAR per night
Guest favorite

Apartment in High Springs

5.0 out of 5 average rating, 191 reviews

The Poe - Stylish Studio Downtown High Springs, FL

Aug 10 – 17

R2,540 ZAR per night
Guest favorite

Farm stay in Middleburg

4.94 out of 5 average rating, 175 reviews

A Private Loft at Grand Landings Equestrian Center

Aug 21 – 28

R2,049 ZAR per night

Destinations to explore

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