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Vacation rentals in Santa Cruz de la Sierra

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Cruz de la Sierra

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favorite

Apartment in Mérida

4.97 out of 5 average rating, 273 reviews

Hipódromo Apartment

It is a renovated apartment next to the Roman Circus/Hippodrome. Easy to park on the same street. 60 m2 overlooking the Roman Circus. Living room with kitchenette, two bedrooms: 1 double and 1 single. Very bright, focused to the south. Cozy and comfortable without noise. Two large plasma TVs in living room and large bedroom. Air conditioning and heating in rooms and living room. All equipped, 10 minutes walk from the center and other monuments. Wifi with cable TV. It is a 2nd floor WITH NO ELEVATOR.

Jul 4 – 11

R1,229 ZAR per night
Guest favorite

Tiny home in Cáceres

4.9 out of 5 average rating, 134 reviews

El Escondite de la Muralla

Enjoy Cáceres from our unique little house. In the heart of the Old Town and with the 12th century Almohad Wall as the main façade, it is a privileged haven of peace, equipped with all the necessary comforts to make your stay in Cáceres an unforgettable experience. It has a double bedroom, a full bathroom with a large shower and a living room with a fully equipped kitchen. It has a charming reading corner and laundry room. There is A/C, Wi-Fi, Smart-TV, Smart-WC... and you can access it by car.

Jul 9 – 16

R1,608 ZAR per night
Guest favorite

Cottage in Pago de San Clemente

4.96 out of 5 average rating, 23 reviews

Casa El Zorzal

Casa el Zorzal is a 4* establishment in the middle of the Extremadura countryside. It is an ideal place for family holidays and also for families with children. It is also a great place for ornithologists and nature lovers. The country house dates back to 1860 and is surrounded by holm oaks, olive and fig trees, on a 10,000 m2 estate with privileged views of the Extremadura dehesa. The area is called Sierra de los Lagares, just a few kilometres from Trujillo, Guadalupe and Cáceres.

Sep 17 – 24

R8,042 ZAR per night

Popular amenities for Santa Cruz de la Sierra vacation rentals

Other great vacation rentals in Santa Cruz de la Sierra

Guest favorite

Cottage in Trujillo

5.0 out of 5 average rating, 29 reviews

Lagar el Altozano

Jun 22 – 29

R11,032 ZAR per night
Guest favorite

Home in La Isla de Valdecañas

4.95 out of 5 average rating, 20 reviews

Villa Island of Valdecañas, South

Sep 22 – 29

R6,310 ZAR per night
Guest favorite

Apartment in Berzocana

4.92 out of 5 average rating, 65 reviews

Cozy and overlooking the valley, A5

Mar 14 – 21

R1,683 ZAR per night
Guest favorite

Apartment in Mérida

5.0 out of 5 average rating, 25 reviews

Petronila 1 Bedroom Apartment

Dec 16 – 23

R2,165 ZAR per night
Guest favorite

Apartment in Trujillo

5.0 out of 5 average rating, 17 reviews

Studio with balcony - Hotel El Baciyelmo

Sep 5 – 12

R1,396 ZAR per night
Superhost

Cottage in Ibahernando

4.84 out of 5 average rating, 69 reviews

A rural house in EXTREMADURA.

May 19 – 26

R4,768 ZAR per night
Guest favorite

Vacation home in La Cumbre

4.88 out of 5 average rating, 25 reviews

Mushara Tourist Apartment

Feb 20 – 27

R2,219 ZAR per night
Guest favorite

Loft in Don Benito

5.0 out of 5 average rating, 24 reviews

New Folin Apartment.

Apr 11 – 18

R1,732 ZAR per night
Guest favorite

Cottage in Campo Lugar

4.81 out of 5 average rating, 26 reviews

Coqueta and cozy cottage in Campo Lugar

Dec 3 – 10

R1,496 ZAR per night
Guest favorite

Villa in El Gordo

4.93 out of 5 average rating, 83 reviews

Luxury Villa in Isle of Valdecañas

Sep 1 – 8

R6,906 ZAR per night
Guest favorite

Apartment in Don Benito

4.98 out of 5 average rating, 57 reviews

Magnificent apartment with an excellent location

Sep 5 – 12

R1,294 ZAR per night
Guest favorite

Place to stay in Mérida

4.96 out of 5 average rating, 51 reviews

Apartment Proserpina, all glass floor

Oct 20 – 27

R3,096 ZAR per night

Destinations to explore