
House vacation rentals in Santa Cruz
Find and book unique houses on Airbnb
Top-rated house rentals in Santa Cruz
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Santa Cruz house rentals
House rentals with a pool

Casa Trébol, your home away from home

casa de campo 2 @casa_elencanto

Know Marchigüe

“El Descanso” family plot

Country house in the heart of the city

HOM I Cozy house in Rapel 12PAX

Newly-equiped house

Leiendo Casa en Lago Rapel
Weekly house rentals

Warm and safe house with garden

House with swimming pool in the foothills, Rio.

Casa Malva, Palmilla, Santa Cruz

Comfortable and quiet house in a family neighborhood!

Cozy and modern cottage

Casa de campo, a 20 minutos de Santa Cruz

Country house 15 minutes from Curicó

Furnished cabin
Private house rentals

A perfect break

Casa Pando in Santa Cruz

Casa Corazón, Valle de Colchagua

Casa Noly

Beautiful Capullos de Luna Shelter

Family plot in Pelequén in private condominium

Charming Country House!

Country House
Quick stats about house rentals in Santa Cruz
Total rentals
60 properties
Total number of reviews
1.3K reviews
Family-friendly rentals
30 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with a pool
10 properties have a pool
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Destinations to explore
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- Rentals with a fireplace Santa Cruz
- Pet-friendly rentals Santa Cruz
- Rentals with pools Santa Cruz
- Rentals with breakfast Santa Cruz
- Rentals with a fire pit Santa Cruz
- Smoking-friendly rentals Santa Cruz
- Rentals with a patio Santa Cruz
- Rentals with outdoor seating Santa Cruz
- House rentals Colchagua
- House rentals O'Higgins
- House rentals Chile