Vacation rentals in St. Ann

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Top-rated vacation rentals in St. Ann

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A well-organized kitchen features dark cabinetry and a light countertop, providing ample workspace. A comfortable couch is positioned in the living area, absorbing natural light from the window. Decorative elements, including a round wall mirror and soft furnishings, add a touch of warmth to the space.
Home in Saint Charles
4.93 out of 5 average rating, 122 reviews

Cottage on Main Street- Low Cleaning Fee

MESSAGE FOR SHORT STAY DISCOUNT Stay in the heart of Historic Downtown St. Charles! WALK EVERYWHERE at this beautifully updated 2BR/1BA blends modern comfort with charm just steps from Main Street. Walk to award-winning restaurants, unique boutiques, coffee shops, festivals, and riverfront views. Directly across from the Katy Trail, perfect for biking and morning strolls. Minutes to Ameristar Casino and 12 minutes to STL Airport. Fast Wi-Fi, cozy beds, and an unbeatable location. See you soon!

Top guest favorite
A modern kitchen area features a contrasting blue cabinetry and wood paneling. A granite countertop adds a stylish touch, complemented by a small sink and utensils displayed in a white container. Natural light enters through a sliding glass door, enhancing the space.
Home in St. Ann
4.9 out of 5 average rating, 80 reviews

Lower Level Layover

Keep it simple at this peaceful and centrally-located place. Located only 6 minutes to the airport. To accommodate our guests we are also happy to drive them to and from for short trips. Our home is walking distance to an AMAZING local cafe- the Sweet Spot! This is the lower level of our home. You will have full access to the lower level and it is completely separate. Entrance is around back through the walk out basement. Sometimes our small girl dogs will be out in the backyard which is shared

Superhost
A light-filled bedroom features a spacious bed layered with a soft blanket and decorative pillows. A vase with flowers sits on the nightstand next to a wall-mounted lamp. Windows dressed with floral curtains provide views of the neighborhood.
Home in St. Ann
4.78 out of 5 average rating, 118 reviews

Cozy Cottage in the City

This stylish place is perfect for your stay while in St. Louis. Whether here for family or business, this home is conveniently located just 15 minutes to Clayton, 20 min to downtown & the Central West End, or 15 minutes to St. Charles County. With only a 7 min drive (if you drive slow!!) to the airport, this 2 bedroom, 1 bath boasts a spacious kitchen, living room, & dining room for your stay-however long it may be! Please note that the piano in the photos is not available for guests to play.

Top guest favorite
Home in St. Louis
4.94 out of 5 average rating, 78 reviews

Serene Stay in St Louis, MO

Bright, cozy brick home with modern updates and plenty of natural light. Enjoy spacious and clean living spaces with a fully stocked kitchen. Relax in peaceful bedrooms and a large backyard. The garage make parking easy perfect for families, couples, or small groups. While hosting, we stay in the basement with our own private entrance. We have very busy work schedule, so we're rarely home. You won’t notice we're there, we strive to ensure your stay feels as quiet and private as possible.

Superhost
A well-lit living area features a dark leather sofa adorned with colorful cushions, complemented by a wooden coffee table and a blue area rug. Artwork and decorative accents enhance the space, with sunlight filtering through the windows, creating a warm, inviting atmosphere.
Apartment in Maryland Heights
4.87 out of 5 average rating, 206 reviews

Stunning Modern Apt| King bed 5 min CreveCoeurLake

Experience luxury and style in our St. Louis home. This second-floor residence features 2 modern bedrooms, a cozy living room, a fully equipped kitchen, a stylish bathroom, and a dedicated workspace with high-speed WiFi- blending comfort and elegance. Located in a secure Maryland Heights community, just minutes from Creve Coeur Lake, Westport Plaza, Hollywood Casino & Amphitheatre, and historic St. Charles. With plush bedding, premium amenities, and ample parking, we promise a seamless stay!

Guest favorite
A well-lit interior space features warm wooden flooring and a soft area rug. Natural light filters in from a nearby window, enhancing the inviting atmosphere of the room. The layout suggests a cozy and functional space suitable for relaxation or entertaining.
Home in St. Louis
4.8 out of 5 average rating, 272 reviews

Cheerful 1-bedroom, red brick, historic home

Keep it simple at this peaceful, historic, and centrally-located place. This red brick home is a piece of long-standing history (built in 1928), on a quiet one way street. It is just 5 minutes away from the airport & University of Missouri Saint Louis, and just 15 minutes from down town and central west end. It is literally central to just about any place you wish to visit in the Saint Louis area! There’s convenient and free on-street parking too! Come enjoy your time at The Ruby Brick Stay!

Top guest favorite
The exterior of the house features a well-maintained lawn with shrubbery and a covered porch. A cozy seating area with a modern coffee table is shown, complemented by a sectional sofa. A well-equipped kitchen with appliances and a dining table set for six are also visible. A serene bedroom showcases a spacious bed with soft linens.
Home in Saint Charles
4.99 out of 5 average rating, 246 reviews

Little House By Main St -5 4K TV's- 1-75 Inch -1GB

Little House By Main St -5 4K TV's- 1-75 Inch -1GB Internet- No location has better access to so much. All the best amenities on both sides of Main Street St Charles! Walking distance from the Ameristar Casino, Texas Road House, Main Street (Honky Tonk, Big A's, Q, Thirstys), Starbucks, Taco Bell, Buffalo Wild Wings, McDonald's and the Bars / Restaurants on Main. An Awesome Location for all of the Festivals in St Charles! And secured parking in the 1 car garage!

Guest favorite
Home in St. Louis
4.9 out of 5 average rating, 42 reviews

International Airport Lambert Home 2BR

Welcome to Mabel’s Cottage. This charming 2BR home is minutes from STL airport. Each bedroom has a plush memory foam king bed. Perfect place for family and friends. **LOCAL GUEST & NO-PARTY POLICY:** Parties or gatherings are strictly forbidden. Local bookings are generally not accepted. Exceptions are for verified emergencies with prior approval. Unapproved local bookings may be cancelled immediately, with financial responsibility per Airbnb policy.

Guest favorite
Condo in St. Louis
4.94 out of 5 average rating, 17 reviews

Cozy and cute - just minutes from West Port Plaza!

Clean & cozy 2 bedroom/1 bathroom condo on second floor - located just minutes away from the airport and West Port Plaza. This unit was fully renovated in Jan 2023 and is ideal for business professionals, students and families. Conveniently located to many restaurants, bars and shops. Easy drive to local hospitals, west county and St. Charles. Just minutes from West Port Plaza and close to major highways - I 270, I 64/40 and I 170.

Top guest favorite
Home in St. Louis
4.97 out of 5 average rating, 146 reviews

Great Location Fam Friendly Home w/Lrg Fenced Yard

Newly finished basement with 4th bedroom (King bed), large play/relaxation space & large 120-inch projector screen and separate large speaker for movie nights! Beds are all brand new comfortable memory foam! This house is in such a great and convenient area! Freshly renovated with all brand new beds and furniture, a fully stocked kitchen for cooking and baking and a fenced in pet friendly backyard! TONS of kids and baby items!

Guest favorite
A cozy sleeping area is presented with a spacious bed covered in dark bedding. A full-length mirror leans against the wall, reflecting the soft overhead light. Thick curtains adorn the window, and a decorative rug covers the floor.
Apartment in St. Louis
4.89 out of 5 average rating, 128 reviews

The Amelia

Cozy studio apartment in Saint Louis close to the Saint Louis International Airport. You’ll be approximately 20 minutes from almost anywhere in Saint Louis: Downtown, Delmar Loop, Zoo, Science Center, Aquarium, shopping centers, and SO much more! With a gated entrance to the property, private keypad entrance, and security cameras this is a perfect place for those looking for a secure place to stay while visiting Saint Louis!

Superhost
A vibrant blue sofa is positioned in a light-filled living area, accompanied by a wooden coffee table. Decorative wall art in muted tones enhances the space. A small lamp stands next to a potted plant, with an open doorway leading to another room in the background.
Home in St. Ann
4.8 out of 5 average rating, 55 reviews

Cozy Peaceful 2 bedroom duplex

Relax and relish the serenity at this beautifully adorned 2-bedroom, 1-bathroom duplex. Recently revamped, it offers cozy living spaces perfect for a small family, friends seeking a retreat, or business travelers. Delight in complimentary coffee, toiletries, and snacks upon your arrival. Just a 5-minute drive from the highway, this tranquil neighborhood provides convenient access to nearby dining and entertainment options.

Popular amenities for St. Ann vacation rentals