Guesthouse vacation rentals in Panama Canal

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Top-rated guesthouse rentals in Panama Canal

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Guesthouse in Panamá

4.76 out of 5 average rating, 242 reviews

Garden Cottage in city center

Cozy Private Cottage in Panama City Enjoy a comfortable stay in this charming garden cottage located in a central area of Panama City. With a private entrance, garden, and outdoor barbecue area, you'll have everything you need for a perfect getaway. The property features WiFi, smart TV, air conditioning, a double bed, and a sofa bed in the living room, as well as a fully equipped kitchen and bathroom. It also includes a washer and dryer for your convenience Perfect for an unforgettable escape

Top guest favorite

Guesthouse in Gamboa

4.95 out of 5 average rating, 75 reviews

Gamboa Toucan Apartment casa # 126

Welcome to Gamboa! Only 35 minutes from downtown Panama, Gamboa. Situated in Soberanía National Park and on the shores of the Panama Canal, is a Mecca for Birdwatchers and Nature enthusiasts! Watch the wildlife right from the backyard of your fully equipped apartment. Feel the magic songs of thousands of birds welcoming the twilight of sunrise and dusk in this century old community. Easily explore wildlife on trials through the surrounding old growth jungle and by boat on the Panama Canal.

Guest favorite

Guesthouse in Panamá

4.92 out of 5 average rating, 36 reviews

Home Harmony 15 min. Aeropuerto.

"Experimenta una estancia cómoda y conveniente en nuestro acogedor apartamento, ubicado a solo 10 minutos del aeropuerto Tocumen. Equipado con todas las comodidades necesarias para tu descanso, desde conexión WiFi hasta una cocina equipada, este espacio te ofrece la oportunidad de relajarte y recargar energías. Disfruta del confort del aire acondicionado, agua caliente/fria en el baño, una cama y sofá cama para tu comodidad, televisión con cable , y toallas y sobrecama para tu conveniencia.

Superhost

Guesthouse in Panamá

Trendy Tiny Apartment in Ancon

Nestled in the former Canal Zone, this cozy apartment offers comfort, nature, and city access. Near the City of Knowledge, The Panama Canal and Albrook, it’s perfect for exploring history and culture. We proudly welcome LGBTQ+ travelers and allies to a safe, inclusive space where you can relax and feel at home. Whether you're a solo traveler, a couple, or a digital nomad, you’ll find a warm, affirming environment here. Enjoy tropical hikes, city views, and local events. 🌈

Superhost

Guesthouse in Panamá

4.75 out of 5 average rating, 4 reviews

The Black Studio near airport & city

This unique PRIVATE place has a style all its own. This stylish place is anything but ordinary. It is affordable and its perfect for a couple or business trips. Conveniently located next to shopping malls and supermarkets you’re literally 3 minutes from the train station and just 20 minutes to the city. Don Bosco is a safe place. Enjoy a cozy place with everything you can need for your stay. This place is private with its private entrance. IT IS NOT SHARED!

Guest favorite

Guesthouse in Panamá

4.88 out of 5 average rating, 17 reviews

Charming Urban Retreat with Private Green Oasis

A peaceful, art-filled retreat in the heart of El Cangrejo. This ground-floor apartment features a private green yard — perfect for relaxing or spotting hummingbirds. There is an outdoor furniture dining set (available upon request). Steps from cafés, galleries, parks, and nightlife, yet quiet and tucked away. Only one neighbor on site. Thoughtfully decorated with pieces from local artisans. Watch the video: “El Cangrejo – Unique Oasis Apartment” on YouTube.

Guest favorite

Guesthouse in Panamá

4.87 out of 5 average rating, 53 reviews

Casa de huésped privada en Ancón

Disfruta de la sencillez de este acogedor alojamiento tranquilo y céntrico. Cerca de lugares de interés como el edificio de la Administración del Canal de Panamá, Amador Causeway, Albrook Mall, y varios restaurantes. Personalmente decorado para proporcionar comodidad... grandes ventanales en el dormitorio proporcionan iluminación natural y una vista del jardín y el área verde a través de las ventanas; aun así mantiene la privacidad y la tranquilidad deseada.

Superhost

Guesthouse in Panamá

4.47 out of 5 average rating, 15 reviews

Conveniente Suite céntrica y con estacionamiento

This special place is close to everything, making it easy to plan your visit. 5-10 minutes to any attraction in Panama City. Assigned parking and two blocks from major bus stop that can take you anywhere in the city or accross the country. You will have the entire place for yourself with independent entry, air conditioning and kitchen. There are four grocery stores walking distance. You can exercise daily at a park located behind the property.

Guest favorite

Guesthouse in Panamá

4.93 out of 5 average rating, 42 reviews

CASA PINO, bosque en la ciudad

Excelente Aparta-estudio independiente con todo lo necesario, Baño Privado, Cocineta Nevera y WIFI. Con mucha seguridad. Pueden utilizar máquinas en el parque para hacer ejercicios. Estamos ubicados en un área privilegiada en las revieras del Canal, con mucha vegetación y bosques, pero muy cerca de todas las amenidades recreativas de la Ciudad del Saber. Muy céntrico, a 10 minutos en metro-bus hasta Albrook Mall, a 10 minutos del Canal de Panamá.

Guest favorite

Guesthouse in Distrito San Miguelito, Brisas del Golf, Panama City

5 out of 5 average rating, 26 reviews

Apartamento en área residencial segura

Estarás cerca de todo cuando te quedes en este alojamiento céntrico. Alrededor de 20 minutos del aeropuerto de Tocumen, 15minutos de Estadio Romel, de paso para Zona Libre Colón cerca de comercios, restaurantes, farmacias, supermercados, cines, facilidad de transporte. Si el viaje es de trabajo, de turista, o en tránsito por Panamá en este apartamento podrás estar con comodidad. Estamos a su disposición si requiere información adicional.

Guest favorite

Guesthouse in Panama City

4.89 out of 5 average rating, 216 reviews

#1 Studio personal 9 km Aeropuerto Internacional

Mini room independiente, Cuenta con A/C , con su baño pequeño. Ubicado cerca del Aeropuerto Internacional de Tocumen, de 10 a 13 minutos en auto. El Studio está Cerca de 2 Centros Comerciales, Metromall y Los Pueblos. La zona residencial es segura al caminar, calles organizadas y limpias. Tenemos la estación del Metro de Cerro Viento afuera en Metromall. Espacio para preparar alimentos ligeros.

Guest favorite

Guesthouse in Panama City

4.88 out of 5 average rating, 74 reviews

Pequeño Anexo estilo Apartamento

El lugar queda serca del aeropuerto de Tocumen (15 minutos), cuenta con WIFI, servicio por cable, Netflix y tiene a su alrededor tiendas y supermercados, muy serca de la naturaleza, es un lugar tranquilo y acogedor. Tambien puedes tomar un Taxi o Uber para llegar al Metro de Panamá (10 minutos) Contamos con servicio de transporte ida y vuelta al aeropuerto de Tocumen, por un costo adicional.