Vacation rentals in Osborn Medical Center, Phoenix

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Top-rated vacation rentals in Osborn Medical Center, Phoenix

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite

Guesthouse in Encanto

4.98 out of 5 average rating, 121 reviews

Best Little Guesthouse in Melrose !

Historic guesthouse in the heart of the Melrose District! EV charger! Walking distance to restaurants, bars, coffee shops, the famous Melrose Vintage shops, grocery stores, LA Fitness and more! Want to head downtown to Chase Field, Talking Stick Arena for a game or a show? Campbell Street Light Rail station is only five short blocks away! No need for a car, you can take the Light Rail from Sky Harbor International Airport, save your money for entertainment! Off street parking if you have a car!

Jan 3 – 10

R1,833 ZAR per night

Guest favorite

Guesthouse in Encanto

4.99 out of 5 average rating, 205 reviews

Historic Phoenix Casita Walk To 27 Holes Of Golf

This 500 sq. foot casita is situated in Del Norte Place Historic Neighborhood directly across from Encanto Park. Forbes named it one of 12 best city parks in America! 222 acres and 7.5 acre/feet of lagoon including Enchanted Island Amusement Park, picnic areas and boat rentals. Only a 5 minute walk to 27 holes of golf & unique family owned restaurants. You're a 5 minute drive to Downtown and a 15 minute walk to Light Rail, Phoenix Art Museum, Heard Museum and restaurants such as famous Durant's!

Jul 11 – 18

R2,037 ZAR per night

Guest favorite

Guesthouse in Encanto

4.95 out of 5 average rating, 261 reviews

Walk to Light Rail! Private Casita

Minutes away from the baseball and basketball stadiums; museums; cultural attractions; St. Joseph's Hospital and Barrow Neurological Institute. A 1/2 block walk to the Encanto/Central Ave. light rail station for easy access from the airport. The perfect location for parents to visit students at Grand Canyon University and Arizona State University. Located on a quiet, pretty palm-tree-lined street with Tudors, Bungalows, and Spanish Colonials. Visit YouTube and search 58 Willo Casita for a tour.

Oct 6 – 13

R2,096 ZAR per night

Guest favorite

Guesthouse in Encanto

4.96 out of 5 average rating, 120 reviews

Adorable Casita in Historic Central Phoenix.

Keep it simple at this peaceful and centrally-located place. This Willo casita is near downtown, unique restaurants, shopping and museums. 1/2 mile from the Light Rail and 10 min to Sky Harbor Airport. The Recently Updated Casita is off the main house but has its own fenced in yard. We have a fridge, microwave, induction cooktop, and Keurig for coffee. Washer/Dryer unit is outside and shared with main house but available if necessary. Sleeps 3 comfortably with pull out sofa. Street parking.

Jul 9 – 16

R1,908 ZAR per night

Guest favorite

Guesthouse in Encanto

4.98 out of 5 average rating, 1078 reviews

Private, Sparkling Clean Historic DTPHX Guesthouse

This charming studio guesthouse in the Campus Vista historic district is a fantastic find! Situated in a friendly neighborhood in the heart of Phoenix, this newly remodeled living space is cozy and practical, surpassing many of the similar properties in quality and character. A short ten-minute drive from the Sky Harbor Airport, and located within walking distance to two major bus lines and the light rail, the guests are sure to enjoy the easy access to all the popular downtown destinations.

Oct 5 – 12

R1,894 ZAR per night

Guest favorite

Guesthouse in Encanto

4.98 out of 5 average rating, 127 reviews

Private Studio-Sized House in Historic Willo PHX

This safe, centrally-located, stand-alone guest house is nestled in a quiet historic neighborhood. You'll be a 15-min walk to world-class museums as well as a broad range of great bars and restaurants. The Encanto light rail stop at the end of our street is an easy $2 fare. Dog walkers, bicyclists, and migrating birdsong make walks a great way to start your day. 2-night minimum required, studio-sized bathroom, absolutely no parties, pets or commercial photography allowed (fines will follow).

Sep 6 – 13

R1,622 ZAR per night

Guest favorite

Guest suite in Encanto

5.0 out of 5 average rating, 215 reviews

Private, desert-chic casita in vibrant Midtown PHX

Welcome to Casita Amelia, a modern rustic retreat central to all the action Phoenix has to offer. Welcoming and cozy, this newly updated private guest suite has all the luxuries of a modern hotel suite while being quietly tucked away in a cute Midtown neighborhood. Walk to Melrose District. You're also just 5-10 mins by car to Uptown & Camelback Corridor, 10 mins to Downtown (Footprint Center, Chase Field, Arizona Financial), 15 mins to Sky Harbor Airport, and 20 mins to State Farm Stadium.

Jun 19 – 26

R1,205 ZAR per night

Guest favorite

Guesthouse in Encanto

5.0 out of 5 average rating, 295 reviews

Urban Green House

The Urban Green House brings farm life to the urban core. We offer fresh eggs from our backyard hens and gardens for guests to enjoy. We also live green-using solar panels, recycling, and composting. The hosts live on the property and are available to meet any needs that arise. We are located in a quiet and safe 1950s neighborhood, close to local restaurants, coffee shops, Encanto park, direct access to both the I-10 and I-17 freeways, and only 8 miles from Phoenix Sky Harbor Airport.

Apr 9 – 16

R1,772 ZAR per night

Guest favorite

Guesthouse in Encanto

4.89 out of 5 average rating, 166 reviews

Private Casita w/ Pool* & BBQ in Historic Melrose

*PLEASE READ HOUSE RULES IN "OTHER THINGS TO NOTE" AREA BEFORE BOOKING* Under no circumstance can one book the Airbnb for another guest . This violates our house rules as well as Airbnb policy. Read more under HOUSE RULES for more details. Our cozy casita is located in the Woodlawn Park neighborhood, a short car ride from the Melrose and Willo Districts. Located near some of the best restaurants in Phoenix, this is the perfect stay for visitors who want to explore the local food scene.

Jul 12 – 19

R1,345 ZAR per night

Guest favorite

Place to stay in Alhambra

4.97 out of 5 average rating, 873 reviews

Uptown area Private guest house suite 1 King Bed

“CHECKING IN INSTRUCTIONS”at “GUEST RESOURCES” on Airbnb Please no early Check In due to time constraints. The guest room has air conditioner/heater/king size bed/linens/Plates/glasses-all plastic, towels/wifi/premium cable with movie channels. Premium internet. Guest house 275 sq feet There is street parking with parking permit available. —— NO SMOKING of tobacco products. NO SMOKING of any products inside guest house Property is 420 friendly only in outdoor spaces.

Oct 11 – 18

R2,325 ZAR per night

Guest favorite

Guesthouse in Encanto

4.95 out of 5 average rating, 137 reviews

Midtown Casita | Heart of PHX w/ full kitchen

Escape to this newly finished modern casita in the heart of midtown PHX for business or pleasure. Located near local/ downtown coffee shops, restaurants, sports venues, and bars. Full kitchen, dining area, and workspace + WiFi for remote workdays. Perfect spot for a quick hangout, or longer term stay. We look forward to making your stay as enjoyable as possible. No smoking of any kind allowed on the premise. Property is cleaned & disinfected in accordance with Airbnb guidelines.

Oct 16 – 23

R2,122 ZAR per night

Guest favorite

Guesthouse in Central City

4.95 out of 5 average rating, 909 reviews

Studio B industrial design

A contemporary industrial designed studio with cement floors and exposed pipes. A grey water system irrigates the lush southwest gardens. Be adventurous and choose the outdoor shower in the enclosed back patio to fully appreciate the warm weather! Tucked away in the historic F.Q. Story Neighborhood in downtown Phoenix. You are surrounded by charming historic homes as you walk the neighborhood. Close to local eats, parks, and museums. EVERYONE is welcome at Studio B!

Mar 29 – Apr 5

R1,746 ZAR per night