Vacation rentals in Murphysboro

Book unique vacation rentals, houses, and more on Airbnb

0 of 0 items showing
1 of 3 pages

Popular amenities for Murphysboro vacation rentals

Other great vacation rentals in Murphysboro

Top guest favorite
Guesthouse in De Soto
4.93 out of 5 average rating, 29 reviews

Farm Views From Cozy Guesthouse

TeriRating, 5 stars2 weeks ago
We were in the area to take care of some family business for a week. Jeff was very accommodating and considerate with our needs. He even supplied fresh eggs from his farm. The house was cozy and clean with beautiful views of Southern Illinois farm land. Very peaceful and quiet, which what we needed during a stressful time. I cannot thank Jeff enough for his hospitality.
Top guest favorite
Cabin in Pomona
5 out of 5 average rating, 93 reviews

Modern Cabin at Trillium Ridge

CallieRating, 5 stars3 days ago
This place was literally perfection! The home was so well thought out, and the small things that the host did really stood out. The location is perfect for a few days away from busy lives and just a slower pace of life. It’s the kind of place you want to tell everyone about but also keep it as your secret getaway. We will be back Hope around the fall. I can only imagine how stunning it is then!
Guest favorite
Cabin in Carbondale
4.93 out of 5 average rating, 27 reviews

Charmful Cabin next to refuge

KelliRating, 5 stars2 weeks ago
My husband I stayed at Linda’s adorable place on a cross-country move. We had driven 13 hours when we arrived and maps delivered us easily. The cottage (best word I can use to describe) was clean and filled with adorable vintage artistic items. My exhausted husband was willing to head into Carbondale for pizza and it was an easy trip there and back (16 mins. Each way). This was a wonderful oasis for us on our journey.
Guest favorite
Cabin in Carbondale
4.91 out of 5 average rating, 34 reviews

Woodhaven Retreat private cabin on secluded acres!

RyanRating, 5 stars3 weeks ago
We absolutely loved our stay at this beautiful property. The home is full of charm, thoughtfully renovated, and incredibly comfortable. We especially appreciated the peaceful, nature-filled setting—secluded enough to feel like a retreat, yet conveniently located. The large atrium windows and striking fireplace create a warm, cozy atmosphere, and the updated kitchen and bathrooms are stunning. We’re already looking forward to our next visit.
Guest favorite
Home in Makanda
4.89 out of 5 average rating, 62 reviews

Cedar Lake Retreat

DonaldRating, 5 stars2 weeks ago
I went to SIUC many many years ago and never visited Giant City. We came down to visit the campus and Giant City and Theresa’s place allowed us to bring our pet and was a great location. It was clean and nicely decorated at a good price.
Top guest favorite
Cabin in Alto Pass
5 out of 5 average rating, 26 reviews

Gram's Cabin at Bald Knob

DeniseRating, 5 stars1 month ago
Really enjoyed Gram's cabin. So peaceful and loved the front porch. Close to wineries and state parks. We visit this area multiple times a year. Went to Bald Knob Cross of Peace and got some great night photos. We felt right at home and will come back.
Guest favorite
Home in Pomona
4.85 out of 5 average rating, 13 reviews

Shawnee Forest Vacation Lodge

JulesRating, 5 stars1 week ago
Kevin’s place was PERFECT!! Super cozy & CLEAN! Our family loved the peaceful, secluded location. Kevin quickly responded any time I had a question and gave us several good recommendations. Our pups felt right at home too. We look forward to staying here again!
Superhost
Cabin in Makanda
4.7 out of 5 average rating, 10 reviews

Shawnee Wine Trail Farm Stay

AndreaRating, 5 stars1 week ago
My husband and I had the best time at the barn bunkie! It was exactly what we were looking for - Quiet, relaxing and cute. We pulled up and were greeted by the world’s sweetest pets! 2 fluffy, friendly dogs and a very chatty cat. It didn’t stop there. Goats and horses galore! My husband works with horses so he loved that. I gravitated towards the goats as they are one of my favorite animals. The bunkie was cozy and had everything you need for a (somewhat) off-the-grid vacation (we recommend bringing a few board games as there is no tv). There is a ladder to get up to the bedroom, but it added to the fun! The bed is very comfortable. Keith and Becky were great hosts! Both very friendly and had great recommendations for food, vineyards and shopping. We will definitely be back!

Quick stats about vacation rentals in Murphysboro

  • Total rentals

    30 properties

  • Nightly prices starting at

    R539 ZAR before taxes and fees

  • Total number of reviews

    1.1K reviews

  • Family-friendly rentals

    20 properties are a good fit for families

  • Pet-friendly rentals

    10 properties allow pets

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

Frequently Asked Questions

  • Are there vacation rentals with a dedicated workspace in Murphysboro?

    Yes! Work meets play with ease at over 10 vacation rentals in Murphysboro featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • How much does it cost to stay in house rentals in Murphysboro?

    Experience the best of Murphysboro with our house rentals, starting at about $30 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

  • Are there pet-friendly vacation rentals in Murphysboro?

    Four-legged friends are welcome in Murphysboro. Choose from more than 10 vacation rentals for guests traveling with pets.

  • Do house rentals in Murphysboro have wifi?

    Absolutely! We offer over 10 house rentals with wifi in Murphysboro. Enjoy a tailored experience with all the comforts you desire.

Destinations to explore

  1. Airbnb
  2. United States
  3. Illinois
  4. Jackson County
  5. Murphysboro