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Guesthouse vacation rentals in Madre de Dios

Find and book unique guesthouse rentals on Airbnb

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Vacation rentals for every style

Get the amount of space that is right for you

Popular amenities for Madre de Dios guesthouse rentals

Kitchen
Wifi
Free parking on premises
Air conditioning

Family-friendly guest house rentals

A simple room is depicted, featuring a wooden ceiling and a ceiling fan. A wooden closet with drawers is visible, along with an open door leading to another space. Natural light enters through a window on the opposite wall.
Private room in Puerto Maldonado

Rooms in Puerto Maldonado

A modern structure featuring large glass windows that provide ample natural light and views of the surrounding greenery. Steps lead from the grassy area to the entrance. The landscape includes blooming flowers and trees, contributing to a peaceful ambiance.
Private room in Calca

HananPacha-Ashram Transpersonal

A bright room features large windows with flowing curtains, allowing natural light to illuminate the space. A spacious bed is adorned with a vibrant floral blanket. Minimalist furnishings, including a small table and chairs, are positioned at the far end, offering a tranquil atmosphere.
Private room in Puerto Maldonado
4 out of 5 average rating, 4 reviews

Comfortable, safe and spacious rooms

A spacious room features wooden beams across the ceiling and a parquet floor. A round table with a white tablecloth and four black chairs is present, alongside a bed with colorful blankets. A large window invites natural light, with a door leading to another area.
Private room in Calca

NuNaTiKaY Healing House

A spacious bedroom is furnished with a bed covered in a striped blanket. A wooden table is positioned nearby, and a television is mounted on the wall. Light hardwood flooring and pale walls create a bright and open feel.
Private room in Tambopata

I rent out furnished rooms

A cozy bedroom is seen through an open door, featuring a floral-patterned bedspread on a spacious bed. Natural light streams through large windows, illuminating the wooden floor and a small bookshelf against the wall. A second bed is visible in the background.
Private room in Yucay

Rooms together for friends in Yucay

A pathway leads through a garden towards a two-story house, flanked by vibrant green plants and blooming flowers. Sunlight filters through the wooden balconies, enhancing the natural beauty of the setting. The surrounding mountains provide a serene backdrop.
Private room in Urubamba

Yogis House Urubamba

A wooden dining table is surrounded by six matching chairs, set against a backdrop of textured stone walls. A glass vase filled with colorful flowers sits at the table's center, while natural light enters through partially closed curtains.
Private room in Ollantaytambo

Accommodation with an incredible view

Guest house rentals with a patio

An open-air common area showcases a wooden table and chairs, with a television mounted on a stand. Lush greenery and tropical plants fill the space, creating a serene atmosphere. The structural elements feature exposed wooden beams and stone walls that enhance the ambiance.
Private room in Tambopata
4.75 out of 5 average rating, 8 reviews

Private room + bathroom w/ shared spaces

A cozy bedroom is featured, showcasing a spacious bed adorned with a textured white coverlet. Natural light filters in through a large glass door, which leads to a serene outdoor area with greenery. Decorative elements include soft curtains and a unique light fixture.
Private room in Urubamba
New place to stay

SamAymara - Pacha Room

A colorful promotional flyer showcases an exploration tour of Manu National Park. Highlights include bird watching, jungle hikes, hot springs, and river swimming, along with accommodations detailed for a comfortable stay. Images of lush greenery and wildlife are presented, promoting an immersive rainforest experience.
Guesthouse in C.p Salvacion

Coco's House

Private room in Calca

Room 2 in Beautiful Guest House

Superhost
A well-lit room features two spacious beds with colorful bed coverings. Natural light pours in through two large windows, while a wooden cabinet and a simple nightstand provide functional storage. The light walls and stone accents create a cozy atmosphere.
Private room in Urubamba

quiet family space

The interior features natural wooden doors and furniture, complemented by a warm color palette. Two beds are draped with vibrant blue textiles, while ample natural light enters through the open door, illuminating the space and creating a peaceful ambiance.
Private room in Urubamba

Jacarandá. Guesthouse

A spacious living area features two large sofas and a sectional, arranged around a coffee table. Natural light enters through several windows. A dining table with chairs is visible, along with a cozy rug and decorative plants accentuating the rustic charm.
Guesthouse in Urubamba

House Accommodation Valle Sagrado Urubamba Cusco

Guest favorite
The vibrant exterior of the eco lodge is adorned with colorful murals, surrounded by lush greenery and flowering plants. A wooden picnic table and a tall stool are placed on a manicured lawn, framed by trees and the distant mountains in the background.
Private room in Ollantaytambo
4.92 out of 5 average rating, 26 reviews

Full Moon Eco Lodge: Chaska 3

Other guesthouse vacation rentals

Superhost
A spacious room is captured featuring a large bed dressed in white linens, complemented by decorative pillows. A chair is positioned nearby, next to a small table with a lamp. Natural light filters in through small windows, illuminating the warm color scheme and rustic wooden beams.
Private room in Yucay
New place to stay

Double room with private balcony. De Alba.

Superhost
A vibrant building is set among lush greenery, featuring a mural with warm colors on its exterior. A large table is positioned in the foreground, with surrounding trees and flowering plants adding to the natural ambiance. The backdrop reveals towering mountains beneath a partly cloudy sky.
Private room in Ollantaytambo

Full Moon Eco Lodge: Rumi 3

Superhost
A bright room features two individual beds with soft white linens, positioned beside wooden bedside tables. A cozy armchair is present, and natural light enters through a nearby window, enhancing the room's airy feel. Two wooden doors lead to additional private areas of the villa.
Private room in Yucay
New place to stay

Cozy Double room with separate beds. De Alba

Superhost
A spacious room showcases a wooden floor and large windows with natural light. A dining area with two decorated chairs and a low table is situated beside a staircase. The room's design includes warm tones, enhancing the overall inviting ambiance.
Guesthouse in Sacred Valley
4.5 out of 5 average rating, 4 reviews

Light Wood - Cabin 2

Superhost
An open and airy room features two spacious beds with soft linens in light tones. Natural light filters through large windows overlooking the garden. A wooden ceiling with exposed beams adds character. A small dining table and chairs are present, enhancing the cozy ambiance.
Private room in Yucay
New place to stay

Double room in the Sacred Valley. De Alba

Guest favorite
A colorful two-story building is highlighted with vibrant murals on its exterior. The surrounding garden features lush greenery and orange flowering plants. A picnic table and stool are visible on the lawn, providing a space for relaxation amidst nature.
Private room in Ollantaytambo
5 out of 5 average rating, 5 reviews

Full Moon Eco Lodge: Maiu 2

Superhost
An open space featuring wooden flooring and natural light from skylights. A cozy seating area with two patterned chairs complements a wooden table set with dishes. A staircase leads to an upper level, while a small kitchen area is visible in the background.
Guesthouse in Sacred Valley
5 out of 5 average rating, 5 reviews

Light wood - Cabin 3

Superhost
A vibrant, three-story building with a colorful mural decorates the exterior, surrounded by lush greenery and blooming flowers. A well-maintained garden area features a picnic table and a wooden stool, set against a backdrop of mountains and a clear sky.
Private room in Ollantaytambo

Full Moon Eco Lodge: Rumi 2

Destinations to explore