Villa vacation rentals in Los Santos Province

Find and book unique villas on Airbnb

Top-rated villa rentals in Los Santos Province

Guests agree: these villas are highly rated for location, cleanliness, and more.

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Guest favorite

Villa in Las Escobas del Venado

5.0 out of 5 average rating, 6 reviews

Villa Tortugas Playa Venao

Enjoy a spectacular Villa, just a short 3-minute walk to the beach in the most exclusive gated community, with security guards, surveillance & parking. There are 2 bedrooms, each with a private bathroom and an extra bathroom for guests, full kitchen, living room, and a beautiful terrace to rest with friends and family. The house has a 65" Samsung Smart TV / Appe TV, 25MB Wi-Fi internet in each room, and air conditioning. Our facilities at the oceanfront clubhouse & restaurant are exquisite.

Aug 7 – 14

R8,327 ZAR per night

Guest favorite

Villa in Las Escobas del Venado

4.88 out of 5 average rating, 8 reviews

Villa Sueño Azul - Playa Venao

Villa Sueño Azul is a modern beach apartment in the most luxarious resort in Playa Venao - 'Blue'. Only 2 minute walking distance from the beach and an exclusive beach club where you will have access to a stunning beachfront infinity pool, delicious restarunt, and a spacious relaxation area. The Blue community is a relaxed, central and secure gated community where you will always be just a few minutes walking distance from the best restaurant, surfing spots, parties and of course - the beach!

Jun 18 – 25

R3,126 ZAR per night

Guest favorite

Villa in Playa Venao

5.0 out of 5 average rating, 22 reviews

Villa Verde - Luxury&Cozy Villa 1BR #26 BlueVenao

Relax & Calm in a cozy villa with an amazing view of the mountains, located in Playa Venao Beach The villa is fully equipped with 1 Queen size bed and a Sofa bed, High Speed Wi-Fi, Netflix, kitchen cooking tools and appliances like stove, oven, dishwasher, microwave, coffee maker, toaster and blender. Also, you will find a complete laundry with washer and dryer, towels for use inside the Villa, as well as for the pool & beach. Bedrooms come with complete bedding clothes/linens and pillows

Oct 17 – 24

R4,025 ZAR per night

Guest favorite

Villa in Pedasí

4.85 out of 5 average rating, 13 reviews

Drone Pedasi Ranch - Beach Pool Folks Fest Fishing

FAMILY or couples will Relax at this peaceful on the beach complete Ranch. Restaurant near by or drive (5) min to Pedasi's Town Center or Children can be kept close, a bunk-bed is near the King Size bed, with TV and Disney channel in the spacious Main room . Two other bedrooms with two Double-Bed each. All rooms with Bathroom and closet. Separate Kitchen & Dinning room with a relaxing view of the Ocean and wilderness. Ask us about tours to Isla Iguana, fishing trip or Horse back-riding.

Jul 2 – 9

R3,430 ZAR per night

Guest favorite

Villa in Las Escobas del Venado

5.0 out of 5 average rating, 6 reviews

Family Perfect Getaway | 3BR Villa 6 @BlueVenao

Set your clock to beach time! Villa-6 is Located in BlueVenao on the Azuero Peninsula, a unique beachfront community and tropical paradise, with miles of amazing beaches. A quick walk and you are on to seek different adventures! It has 3 bed/3bath, 2 with a Queen bed, and the 3rd w/2 twin/twin bunk beds sized for kids or young adults (not recommended for full grown adults as it might not be comfy). Living, Kitchen and a Terrace fully equipped to relax and enjoy your friends/family getaway!

Feb 14 – 21

R5,934 ZAR per night

Guest favorite

Villa in Cañas

5.0 out of 5 average rating, 15 reviews

Residence Denter Tumas

We long for magnificence, seeking it out in all we do and wherever we travel. Can you imagine a better scenario for a uniquely curated residence than between green hills where both legend and myth come alive? Here you will feel like time has stopped and been replaced by a mysterious silence you can only recognize as pure energy. Come create extraordinary memories that will be forever woven into the fabric of what we call life, where luxury and style meet paradise in a truly unique estate.

May 11 – 18

R9,249 ZAR per night

Guest favorite

Villa in Playa Venao

4.98 out of 5 average rating, 61 reviews

Casa Aqua: Amazing beach front house - Playa Venao

Exceptional beach front property, Casa Aqua sits right on the beach of Playa Venao Bay where you can enjoy great surfing, fishing, whale watching and many other outdoor activities. Casa Aqua is a very spacious 3,500ft home with all amenities you could dream of. You will love to eat/lounge outside in the spacious covered terrasse or swim in the large infinity pool. And if you don't feel like cooking, there are some quality restaurants close by a short walk on the beach from Casa Aqua.

Oct 9 – 16

R11,660 ZAR per night

Guest favorite

Villa in Playa Venao

4.92 out of 5 average rating, 24 reviews

Villa La Piragua : 3BR Surfside Retreat : 5-7G

Welcome to Villa La Piragua, an enchanting sanctuary in Blue Playa Venao. Let yourself go in this tropical paradise with pristine beaches. This beautiful villa offers 3 comfortable bedrooms and 3 well appointed baths. Two bedrooms have dreamy queen beds, while the third features a bunk bed with a pullout and an additional twin bed. All bedrooms have smart TV's and WiFi. Enjoy a serene spacious atmosphere in the living area, kitchen, and terrace, ensuring a memorable family getaway.

Feb 7 – 14

R6,660 ZAR per night

Villa in Playa Venao

4.8 out of 5 average rating, 40 reviews

Villa Nomada - Barefoot Luxury 👑 Beach Front Villa

Ocean front, barefoot luxury, 4 rooms with king bed, 1 nanny's room with queen bed, equipped kitchen, 4.5 bathrooms and a private pool on the beach 🏝 Villa Nomada is a hand crafted masterpiece, for the new age Nomadic lifestyle. It’s unique architecture invites the outdoor in, Using local elements, built on site such as roof tiles & pottery, furniture, doors and decks. On IG @villanomada *A 10% tax will be collected separately as Airbnb do not collect tax in behalf of the host. *

Aug 18 – 25

R12,407 ZAR per night

Superhost

Villa in Playa Venao

4.86 out of 5 average rating, 14 reviews

Villa Best Located in Blue | With Private Pool

Vivienda en Playa Venao; con todo lo necesario para pasar unas excelentes vacaciones con familiares o amigos. 7 personas incluyendo bebés y niños. Se pueden adicionar personas con costo extra. La vivienda es parte de un proyecto privado con garita de seguridad y estacionamiento gratuito. Disfruta de Playa Venao, con sus magníficas olas, disfrutar de un tour a Isla Iguana, hacer yoga, comer delicioso, disfrutar de la vida nocturna y de la naturaleza... todo en este paraíso tropical.

Aug 12 – 19

R6,509 ZAR per night

Villa in Cambutal

4.52 out of 5 average rating, 23 reviews

Pacific Escape

Pacific Escape looks out over an expanse of pacific ocean and protected reef. The 2 bedroom, 2 full-bath home has panoramic views of the ocean, mountains, and reef. Yet, it is close to the beach, restaurants and dining, and family-friendly activities. You’ll love the expansive oceanside porch, high ceilings, the ocean views from bedrooms and living room, and the ambiance. The villa is great for couples and families (with kids) because it sits at the top of a private gated road.

Mar 5 – 12

R2,487 ZAR per night

Superhost

Villa in Las Escobas del Venado

4.95 out of 5 average rating, 21 reviews

Breathtaking Ocean Villa. Casa de Vida

This modern and spacious villa is the perfect vacation home. Tall ceilings, amazing views, huge entertainment/kitchen area, beautiful garden, big pool and lots of space to spread out. Bring your group for a yoga retreat, surf camp, or family get away. Rental includes concierge service to assist in arranging activities, transportation, deliveries, services, whatever you need. Tired of cramped or crowded rentals? Casa de Vida will relax and amaze you.

Oct 7 – 14

R11,023 ZAR per night