Vacation rentals in Keowee

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Top-rated vacation rentals in Keowee

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A treehouse surrounded by trees glows gently with warm lights in the evening. Two Adirondack chairs are positioned around a fire pit, with a small table nearby. The forest setting offers a calm and inviting atmosphere for outdoor relaxation.
Treehouse in Mountain Rest
5.0 out of 5 average rating, 490 reviews

THE BELLA LUNA Romantic Treehouse - Outdoor Shower

This is the perfect ROMANTIC ESCAPE! Located in the Sumter National Forest the Bella Luna is just 5 minutes from Stumphouse Tunnel, Issaqueena Falls, Yellow Branch Falls hiking trail, and Stumphouse Mountain Bike Park and within an hour of Clemson, Lake Jocassee and Clayton, GA. Our romantic retreat features carefully curated vintage furnishings, an outdoor shower, napping net, relaxing seating areas and an outdoor fire pit stocked with firewood and a S’mores kit! We can't wait to host you!

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Superhost
The exterior of a renovated farmhouse is showcased, featuring a gravel driveway and a spacious front porch. The structure exhibits a light-colored façade with multiple large windows, surrounded by trees and open space in a quiet residential setting.
Home in Clemson
4.98 out of 5 average rating, 110 reviews

5 BR/5BA house in the heart of Clemson

Completely updated and remodeled one of a kind farmhouse on .97 acres, minutes from the Clemson campus. Perfect getaway for families or groups in town for Clemson events or time on the lake. Large, eat in kitchen on main level with two living areas. 2 BR/3 BA on main level, 3BR/2BA on second level. Home is pet friendly with a maximum of 2 pets for an additional $50 per stay in addition to the $150 cleaning fee. No parties or excessive noise as the home sits in a quiet residential area.

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Guest favorite
A comfortable living room is presented with two sofas, a wooden coffee table, and a rustic stone fireplace. A television rests on a wooden media console, while natural light enters through nearby windows. The flooring is finished in a warm tone, creating an inviting space.
Home in Seneca
4.95 out of 5 average rating, 208 reviews

Private lake setting close to Clemson University

House is located in a private community yet only 2.5 miles to Death Valley and Clemson. Enjoy a walk down to the lake or relax on the back deck. WIFI is included with access to Hulu and Disney+. Kid friendly as well. Property is also within 1.2 miles of Oconee Airport, 0.7 miles to a dock, 1.5 miles to the grocery store, and less than 1.3 miles to Y beach public parking (avoid game day traffic if you are coming in for football). Close to everything in Oconee, Pickens and Anderson Counties.

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Top guest favorite
An aerial view of a spacious two-level brick home is presented, showcasing a large parking area in front with two garage doors visible. Surrounding greenery enhances the setting, while the property is bordered by trees, providing a sense of privacy.
Home in Anderson
4.94 out of 5 average rating, 145 reviews

Clemson Lake Hartwell Waterfront, Pontoon Rental

Come and enjoy a relaxing family vacation on beautiful Lake Hartwell in this spacious 2 level home. Plenty of room for multiple families to share. This 7600 sq. ft lakefront home sleep up to 18 featuring 7 bedrooms with 1 additional rooms with sofa beds; 5 full-sized bathrooms; 1 laundry area with 2 washers & 2 dryers. Each level boasts a fully furnished kitchen along with a large entertainment area. Breakfast area off main kitchen in addition to a spacious dining room that seats up to 10.

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Guest favorite
A cozy living area is featured with a dark blue sofa, accompanied by an orange loveseat and additional patterned seating. A round coffee table sits at the center, and a decorative rug adds warmth to the wooden floor. Soft lighting is provided by a table lamp.
Condo in Clemson
4.96 out of 5 average rating, 194 reviews

Renfrow's Retreat

Whether you're here for the big game, visiting your favorite college student, touring your future university, or just visiting beautiful Clemson, SC, Renfrow's Retreat is the ideal place to call "home" for your visit. Downtown Clemson and lots of great restaurants are walking distance along with free bus service around town. If staying in is preferred, you have a fully equipped kitchen and dinning table, comfortable living room with WiFi and a smart tv with preloaded streaming services.

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Top guest favorite
Home in West Union
4.98 out of 5 average rating, 45 reviews

Lakefront Private Cove with Boat/Jet Ski Options

✨ Welcome to Cabin By The Cove — your private waterfront playground on Lake Keowee. Set on two quiet acres with a sandy beach, pickleball, private dock, hot tub, game room, and endless lake toys, this home is designed for unforgettable family trips, lake weekends, and Clemson getaways. With room for 14 guests, boat & jet ski rentals on site, and activities for all ages, this is where memories are made from sunrise to starlight. 20 mins to Clemson Competitive priced watercraft rentals

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Top guest favorite
Home in Clemson
5.0 out of 5 average rating, 24 reviews

Calhoun Cottage

Welcome to a sweet little retreat located in the Old Calhoun district of Clemson, SC . This newly renovated 2 bedrooms/2 bath house with a pull-out couch sleeps a total of 6 . Memorial Stadium, downtown and campus are all within walking distance. Public access to Lake Hartwell is conveniently located less than one mile away at Twelve Mile Park. Additionally, The Clemson Experimental Forest with access to miles of hiking , biking and horseback riding trails is under 10 minutes away.

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Guest favorite
A spacious sunken living area features a large brick fireplace as a central focal point, flanked by two inviting seating arrangements. Natural wood beams extend across the ceiling, and light fills the space through multiple large windows, creating a warm and welcoming environment.
Home in Seneca
4.94 out of 5 average rating, 78 reviews

Lakefront Mid-Century Dream Home / 3 mi to Clemson

We excitedly invite you to come enjoy a one of a kind experience at our personal lakefront home. Originally designed and built in the 60s, this home now has all the modern necessities, yet still brims with endless midcentury charm. Located only 3 miles from Clemson, our large outdoor entertainment space and direct access to our private dock invite you to enjoy the many sights and sounds that the lake has to offer. Use our 2 kayaks and canoe, or use the dock to tie up your own boat!

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Guest favorite
The bedroom features a spacious bed with plush pillows and a textured bedspread. A stylish chandelier illuminates the room, complemented by natural light from two large windows. Decorative wall accents and a soft area rug enhance the inviting atmosphere.
Cabin in Seneca
4.89 out of 5 average rating, 175 reviews

Clemson- 5 Min | Hot Tub | Game Room | 5 King Beds

5 minutes to Clemson University & Lake Keowee with a private saltwater hot tub, full arcade-style game room and stocked bar—perfect for families or game-day groups! 4 spacious bedrooms, 7 total beds High-speed Wi-Fi & smart TVs in every room Outdoor deck with grill, fire-pit & cornhole Fully equipped kitchen + coffee bar Rated 4.9★ by 171 guests and hosted by a local husband/wife team who lives nearby for quick help. Book your Clemson retreat today—dates fill fast!

ValueLocationOutdoor spaces

Guest favorite
A bright and spacious kitchen features a central island with a granite countertop, surrounded by blue upholstered chairs. A dining table with wicker chairs is located nearby, and natural light fills the room through sliding glass doors leading to the outdoor area.
Home in Seneca
4.96 out of 5 average rating, 149 reviews

5 Min to Clemson | Large Driveway & Self Check-In

Welcome to your Cozy Family Home! Escape to this charming 3-bedroom, 2-bathroom home, just a short 3-mile drive from the iconic Clemson Memorial Stadium. Whether you're planning a trip to the lake, tailgating for the big game, catching up with friends, or exploring the local hiking trails, this quiet and convenient home is your ideal base. Can't wait for you to enjoy Clemson, SC. Go Tigers! Pet Fee of $100.

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Top guest favorite
A bright living space features wood-paneled walls and multiple large windows allowing natural light to illuminate the area. A long wooden bench runs along one wall, complemented by a rustic dining table and chairs, creating a cozy atmosphere.
Home in Anderson
4.96 out of 5 average rating, 189 reviews

Lake Hartwell House - Cozy and Close to Clemson!

Quiet house on Lake Hartwell. Fully equipped kitchen and beautiful finishes. Great place to stay for Clemson football, time with family or personal retreat. Courtesy use of the dock for swimming or boat. Close to Green Pond Landing and Portman Marina. Great restaurants nearby as well as shopping and outdoor activities. 15 min from Clemson University, 20 min to downtown Anderson, just 10 min from 1-85.

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Guest favorite
A charming cottage is set amongst trees and greenery, featuring a welcoming front porch with wooden railings. The entrance is flanked by neatly trimmed bushes, and a gravel driveway provides access to the property. Natural light filters through the foliage surrounding the home.
Home in Clemson
4.94 out of 5 average rating, 221 reviews

Clemson House 1 mile from Campus!

Welcome to your cozy home away from home in Clemson, SC! This inviting 3-bedroom, 2-bath cottage is less than a mile from Clemson University, making it the perfect spot for Tiger fans, alumni, and families visiting campus. Whether you’re in town for a Clemson football weekend or just soaking in the college town charm, this home has everything you need for a comfortable and memorable stay!

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Popular amenities for Keowee vacation rentals