
Guesthouse vacation rentals in Johns Island
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Top-rated guesthouse rentals in Johns Island
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Johns Island guesthouse rentals
Family-friendly guest house rentals

The Crescent Moon | A Cozy Haven for Two

The Cottage for Two

Centerville Loft, Studio Apt on James Island

New Loft in Historic Summerville

Amenities! Beach/DT 10m 5bed 3br

#1 SC AIRBNB IN MT. PLEASANT OLD VILLAGE. BEACHES!

Indigo House Poolside Retreat

Creekside Cottage (Tiny Home)
Guest house rentals with a patio

*Old Village/Shem Creek Charmer*NEW 2BR Guesthouse

Quaint Cottage Studio in Ashley Forest (Avondale).

Studio 77 in dt Charleston with bikes

Coastal Charm: Village Hideaway

Spacious 1 bedroom cottage in Avondale

My Happy Place

The Violet Villa w/no cleaning fee

5 Star Private Guest House • Heart of Park Circle
Guest house rentals with a washer and dryer

Island Oasis Hideaway | Easy Beach & City Access

CHS Guest house w/ Pool on Golf Course

Summerville’s Tiny Oak Hideaway

Cozy Park Circle, Charleston Guest House

Old Village Guesthouse walkable, close to beach/DT

The Guesthouse at Old Orchard

Spacious Daniel Island Apartment

Guesthouse Convenient to Charleston, Shem Creek, and Beaches
Quick stats about guesthouse rentals in Johns Island
Total rentals
40 properties
Nightly prices starting at
R1,041 ZAR before taxes and fees
Total number of reviews
6.8K reviews
Pet-friendly rentals
10 properties allow pets
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Wifi availability
40 properties include access to wifi
Destinations to explore
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- Pet-friendly rentals Johns Island
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- Family-friendly rentals Johns Island
- Guesthouse rentals Charleston County
- Guesthouse rentals South Carolina
- Guesthouse rentals United States
- Park Circle
- Hunting Island State Park Beach
- Sullivan's Island Beach
- Bulls Island
- Middleton Place
- James Island County Park
- Waterfront Park
- The Golf Club at Wescott Plantation
- Shem Creek Park
- Angel Oak Tree
- Harbor Island Beach
- Hampton Park
- Secession Golf Club
- The Charleston Museum
- Driftwood Beach
- Morris Island Lighthouse
- Isle of Palms Beach
- Bull Point Beach
- Seabrook Island Beach
- Hunting Island Beach
- Charleston Aqua Park
- Gibbes Museum of Art
- White Point Garden
- Seabrook Beach