Vacation rentals in Isthmus of Panama

4.97 out of 5 average rating, 151 reviews

An open living space features a wooden dining table surrounded by six wicker chairs. Two hanging hammocks are displayed on the covered terrace, offering views of the lush hills. Large glass doors reflect the greenery, blending indoor and outdoor spaces harmoniously.

Cabin in Torio

Cozy open space, unique jungle views, river access

Casa Corotu is located in Torio Hills a 10 minute's walk to the beach with a a trail to access Torio river. Fiber Optic WiFi and two work spaces. The property surrounded by big trees that keep the house cool, which also provide shelter for birds and wildlife. The house is NOT childproof, minimal railing system. It's a great house to live the experience of #toriolife and all it has to offer. It is also an opportunity to experience the jungle in an open-style home with a mesmerizing treetop view.

4.98 out of 5 average rating, 160 reviews

An aerial view of the property showcases a spacious layout surrounded by lush greenery. A large saltwater pool and a hot tub are visible alongside a well-maintained outdoor area with red umbrellas providing shade. The roof of the main structure features a brown tone, blending with the natural surroundings.

Home in Costa Esmeralda

Beach House-Amazing Pool, Surf & Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise. Majestic Sands is located in a private beach community in Costa Esmeralda, San Carlos District, Panama. It is located a few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, Santa Clara and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.

4.93 out of 5 average rating, 225 reviews

Cabin in Chicá

Horizonte Cabin by Casa Amaya

Take it easy at this unique and tranquil getaway at Cabaña Horizonte. Casa Amaya is a complex of 6 cabins located in Chicá de Chame, a cool climate between 18 and 24 degrees, where you can connect with nature and relax with your partner, friends or family. https://www.airbnb.com/h/miradorbycasamaya https://www.airbnb.com/h/lospinosbycasaamaya https://www.airbnb.com/h/buenavistabycasaamaya https://www.airbnb.com/h/panoramabycasaamaya We have an electric generator in case of power outages.

Apartment in Nueva Gorgona

A resort-style pool area is surrounded by palm trees and landscaped greenery. Lounge chairs are arranged around a spacious deck, with a large umbrella providing shade. The infinity pool reflects the sky, offering a serene view of the surrounding area.

4.95 out of 5 average rating, 101 reviews

Amazing view! Beachfront @Nueva Gorgona Bahia

Luxury Apartment, Ph Bahia Resort, near of Coronado with 2 bedrooms and one with a fascinating ocean view, living room with sofa bed, dining room, kitchen, terrace and 2 full bathrooms. Totally new and with luxury finishes. Building "Resort Hotel" type, with direct access to the beach and 4 private pools, with Restaurant, Snack Bar in the pool area, and a Beach Bar with music at night in front of the sea, with Tennis, Volleyball, Basketball court , playground, billiards, private parking.

Earthen home in El Cope, Penonome

The modern house is set against a backdrop of rolling mountains, illuminated by the soft glow of evening light. A spacious entrance is visible, with large sliding doors opening to inviting communal areas. Lush greenery surrounds the property, enhancing its natural appeal.

4.92 out of 5 average rating, 177 reviews

Beautiful Eco House in Panama

We are very pleased to offer our beautiful, modern, comfortable house designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and escape daily stress. It is in a beautiful part of Panama near a cloud forest national park. The house sits in 17 acres of forest and has 2 rivers for swimming. The house is very open allowing full enjoyment of nature. There are amazing hiking opportunities in the mountains with waterfalls and visits to local communities.

4.97 out of 5 average rating, 100 reviews

Large glass doors frame a view of lush greenery, connecting the interior to the outdoors. Warm lights illuminate the space, while a hammock hangs above, adding a relaxing touch. The entrance features a wooden door, providing a welcoming contrast to the surrounding nature.

Cabin in Penonome

Aqeel cabin in the nature

Relax at this unique and tranquil getaway surrounded by nature. If you're lucky, you may wake up to see white-faced capuchins from your bedroom window and spot an abundance of birds, such as the crested oropendola or a toucan. The property offers river access with a sandy, beach-like area, and there is a 1 km walking trail alongside the river. With satellite high-speed internet access, you'll stay connected, though the river and sandy area may not be accessible during rainy days.

4.96 out of 5 average rating, 190 reviews

Home in Taboga Island

Casa Rosie - Dream Home on Tabogá Island

Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Home in Vista Mar Golf, Beach & Marina

A contemporary bathroom features a round, illuminated mirror above a textured wooden vanity. A stylish sink is positioned on the countertop, complemented by a woven basket filled with towels. Soft lighting highlights the wood paneling and sleek tiles, creating a serene atmosphere.

4.88 out of 5 average rating, 251 reviews

Luxurious Beach House - Private Pool Golf & Marina

Vista Mar Golf, Beach & Marina is a gated community with private security, with direct access to a state of the art golf course designed by J. Michael Poellot. It also has marina, heliport, tennis courts, direct private beach access, bars and restaurants. The house comes with an outdoor private pool & hot tub, also a amazing private outdoor kitchen, and an amazing sea view with spectacular sunrises and sunsets. any inquiry please contact 66168596

Treehouse in Provincia de Bocas del Toro

The interior space features natural wood construction with transparent walls. A wooden sofa, adorned with decorative cushions, faces a low coffee table. Adjacent, a simple wooden bench provides extra seating. Nearby, a staircase leads to an upper level, framed by lush greenery visible through the walls.

4.92 out of 5 average rating, 224 reviews

Cocovivo Mangrove Treehouse

This secluded loft-style treehouse sits on stilts above the water, 30 feet from our colorful coral reef. Transparent and airy but bug proof walls let you enjoy the fresh ocean breeze and views while keeping you safe and cozy. When a sloth comes to visit, no need to leave the house to see him! Blend in with the surroundings of mangrove, lagoon and jungle, and enjoy water and reef access from your own deck. Bright and airy, 100% eco-conscious.

Cottage in Altos del Maria

An inviting infinity pool is positioned on a spacious patio, overlooking a sweeping mountain view. Two lounge chairs are arranged on the deck, facing the water, while lush greenery and colorful blooms enhance the serene environment surrounding the pool area.

4.94 out of 5 average rating, 147 reviews

Mountain Cottage with Great View and Heated Pool

Mountain Cottage, with spectacular views of the Altos del María Mountains, perfect for relaxing or spending time with the family. It features a heated pool, spacious outdoor spaces, Smart TV and A/C in all rooms and living room, Wi-Fi throughout the property, and is fully equipped. Includes Prime Video service. It also has a fire pit and a gas BBQ. Complimentary late checkout is available for rentals departing on Sundays.

Earthen home in playa el arenal pedasi

A spacious living area features a cozy seating arrangement with plush cushions and a low wooden coffee table. A large hammock hangs nearby, and natural light filters through the windows, illuminating the handcrafted wooden beams and spiral staircase leading to the loft.

4.97 out of 5 average rating, 149 reviews

Earth House Pedasi Experience

Welcome to the Earth House. This space is destined to give you the experience of spending your vacations in a Eco House with all the amenities and facilities of a ¨Regular Home¨. Why Eco? This house is made with 95% adobe and with natural materials from the surroundings like rock and wood. Everything is handmade for this unique space. It is a wonderful experience to share with family and friends.

4.9 out of 5 average rating, 289 reviews

A dining area is presented with a wooden table set with plates and utensils. Large, framed windows allow natural light to fill the space, revealing views of the surrounding greenery. The rustic ambiance is enhanced by wooden accents and woven elements along the windows.

Farm stay in Santa Fe

Santa Fe villa with a espectacular view

Spectacular contemporary style villa surrounded by local flowers and woods. The villas design enhances the relationship with the outside environment with panoramic windows which are found in the dining room and kitchen, this offers an awesome view of the mountains and green flora. The villa is located in a organic quiet farm, with abundant vegetation and great presence of birds.

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Popular amenities for Isthmus of Panama vacation rentals

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Pool

Free parking on premises

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Other great vacation rentals in Isthmus of Panama

Dome in El Valle de Antón

A scenic outdoor area is visible, featuring well-maintained garden beds and natural landscaping. Stone pathways lead to cozy seating arrangements surrounded by lush greenery. A mountainous backdrop is illuminated by morning light, contributing to a peaceful ambiance in the serene atmosphere.

4.9 out of 5 average rating, 48 reviews

5 minutes from Valle I Domo No. 7

SherleyRating, 5 stars2 days ago

I love it, I love it, I love it 100%. It's really 5 minutes from the valley, the instructions are super easy. The Google Maps map gives the exact location, so it was all 10/10 and the communication with Nestor was also excellent. I recommend it without hesitation, good value. Spectacular.

Guesthouse in Panamá Oeste

4.76 out of 5 average rating, 122 reviews

Mountain house with pool in Panama

AnaRating, 5 stars2 weeks ago

Jose’s property is so beautiful. We enjoyed exploring this property and I would love to host a wedding or event here.

4.78 out of 5 average rating, 55 reviews

Home in Chame

P/Caracol Ocean Haven View (C5-PBB) 2 bed, 2 bath

AlexanderRating, 5 stars1 month ago

Great stay. The place was as described and the views were just amazing! Living right on the beach - great. There are some restaurants nearby (e.g. Surf Shack) with top dishes, cocktails and absolutely friendly staff. It was a wonderful stay and the reliable and extremely friendly communication with the host also contributed to this. We will be happy to come back!

Place to stay in Altos del Maria

Floor-to-ceiling glass walls provide breathtaking views of the mountains and sky, allowing natural light to flood the open living space. A swing chair and a wooden dining table are visible, enhancing the connection with nature in this unique environment.

4.77 out of 5 average rating, 238 reviews

Mountain Nature and Architectural Paradise Loft

MarissaRating, 5 stars1 week ago

We absolutely loved this mountain retreat. The open concept & jacuzzi let us enjoy all the incredible nature that surrounded us. Comfortable & modern furnishings in a remote setting, exactly what we wanted!

5 out of 5 average rating, 5 reviews

An outdoor seating area features four rattan chairs with white cushions positioned around a round coffee table. The space overlooks a private swimming pool surrounded by palm trees, creating a relaxed setting for guests to enjoy.

Home in San José

25% OFF Casa Lirios Mini Resort House @ Punta Barco

MicahRating, 5 stars2 weeks ago

The place was great, and incredible for the price. It was just the perfect escape close to the beach.

4.93 out of 5 average rating, 91 reviews

Villa in Rio Hato

Beach Front Paradise!

JoyceRating, 5 stars2 months ago

This place was a wonderful place to relax, enjoy the fresh ocean air and go for quiet walks on the beach. Very quiet, secluded. The host is wonderful and will help with any questions - and went out of his way to help our son who received a jellyfish sting.

5 out of 5 average rating, 26 reviews

Bungalow in Jaramillo

Panoramic Views Pacific to Baru, Boquete District

ChrisRating, 5 stars2 weeks ago

If you are looking for a modern, clean, functional casita in an absolutely tranquil and relaxing spot…..This is it! Wake up to the sounds of beautiful birds every morning. Open the curtains to see the lush flora and fauna of the stunning property. Enjoy a cup of local coffee (provided by the host) on the lower patio for views of the Pacific Ocean, Vulcan Baru and the town of Boquete below. Nothing more peaceful than the serene air of the cloud forest. All or your worries and woes will melt away. Although you might not want to leave the property, you are only a short drive from all that Boquete has to offer. The host, Sherry and Troy are wonderful. They are very helpful and informative. Anything you may need they will assist. This is a five star experience. Highly recommend by my wife and I. We cannot stop thinking about it since we have arrived back home.