
Hotel vacation rentals in Guadalupe County
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Top-rated hotel rentals in Guadalupe County
Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Guadalupe County hotel rentals
Family-friendly hotel rentals

Spacious 2-bed ADA Room,Free WiFi

Hacienda Suite | Workspace | Bar | Pool | River

Newly renovated King room.

King Suite with Kitchenette

Spacious ADA Queen Bed|Free Parking

Extended Family Suite-River View

Del Rio Double Room | River View | Pool | Bar

Double Queen Deluxe | Gruene River Outpost Lodge
Hotel rentals with a pool

King Bed | Workspace | Bar | Pool | River Access

Deluxe Double Room | Bar | Pool | River Access

King Bed Guadalupe River | Pool | Newly Renovated

Sweetwater @ Gruene Cottages

Felsen @ Gruene Cottages

Comfort @ Gruene Cottages

#3| Private Condo| Gruene Hall 0.7mi

Rosemary @ Gruene Cottages
Hotel rentals with a patio

Sonora @ Gruene Cottages (Sonora @ Gruene Cottages)

Sophie's Gasthaus - Karbach Room • Private Balcony

Sophie's Gasthaus- Seele Two Room Suite • 2 Queens

Utopia @ Gruene Cottages

Scrabble Room, Queen Bed-Sleep, Spell, & Score Big

Sophie's Gasthaus - Fischer King Room • Downtown

Sophie's Gasthaus- Prince Solms King Rm • Downtown

Sophie's Gasthaus - Captain's King Room • Downtown
Destinations to explore
- Rentals with lake access Guadalupe County
- House rentals Guadalupe County
- Cottage rentals Guadalupe County
- Rentals with a fireplace Guadalupe County
- Rentals with pools Guadalupe County
- Rentals with a washer and dryer Guadalupe County
- Tent rentals Guadalupe County
- Townhouse rentals Guadalupe County
- Rentals with a hot tub Guadalupe County
- Rentals with outdoor seating Guadalupe County
- Cabin rentals Guadalupe County
- Bed and breakfasts Guadalupe County
- Rentals with a patio Guadalupe County
- Fitness-friendly rentals Guadalupe County
- Waterfront rentals Guadalupe County
- Condo rentals Guadalupe County
- Guesthouse rentals Guadalupe County
- Rentals with a kayak Guadalupe County
- Apartment rentals Guadalupe County
- Villa rentals Guadalupe County
- Rentals with a fire pit Guadalupe County
- Family-friendly rentals Guadalupe County
- Rentals with breakfast Guadalupe County
- Pet-friendly rentals Guadalupe County
- Tiny house rentals Guadalupe County
- Hotel rentals Texas
- Hotel rentals United States
- San Antonio River Walk
- Six Flags Fiesta Texas
- Alamodome
- Schlitterbahn
- Mueller
- Blue Hole Regional Park
- Zilker Botanical Garden
- AT&T Center
- Natural Bridge Caverns
- Guadalupe River State Park
- McKinney Falls State Park
- Morgan's Wonderland
- Lady Bird Johnson Wildflower Center
- Circuit of The Americas
- Mount Bonnell
- Brackenridge Park Golf Course
- Canyon Springs Golf Club
- Palmetto State Park
- San Antonio Botanical Garden
- The Bandit Golf Club
- Blanco State Park
- Austin Convention Center
- Wimberley Market Days
- Landa Park Golf Course at Comal Springs