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House vacation rentals in Guadalupe

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Top-rated house rentals in Guadalupe

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Guest favorite
A cozy bedroom features a spacious bed adorned with decorative pillows. A striped hammock chair is suspended beside the bed, providing a comfortable spot for reading or relaxation. Soft natural light enters through the window, emphasizing the serene color palette.
Home in Arroyo Grande
4.92 out of 5 average rating, 346 reviews

Beach-themed farmhouse with indoor fireplace

As 13-time Superhosts- we welcome you to the perfect place to relax & unwind after your day. This stylish and spacious home offers a sunny deck, surrounded by trees for sunbathing or watching the sunset. The huge 2nd bdrm is a great place for reading in our hammock chair or for a quiet work space. Downstairs the fully equipped kitchen has everything you need for cooking meals. Outdoor patio is a nice place to bbq & relax as you listen to the hawks, owls, & other birds in this country setting.

Guest favorite
A sunset sky filled with vibrant colors casts a warm glow over the country house. The exterior is highlighted by large windows and a welcoming entrance. The driveway leads towards the home, bordered by manicured landscaping, set against a backdrop of rolling hills.
Home in Arroyo Grande
4.83 out of 5 average rating, 281 reviews

Coastal Getaway, Country House, near 101 FWY

Country house surrounded by trees with many windows, wooden floors, lovely kitchen, large sunroom, and huge deck. All located just minutes from Pismo, Grover, Shell and Avila Beach, hot springs, hiking areas, wineries, golf courses, Lake Lopez, ATV riding & outlet shopping, Trader joe's and many other stores. San Luis Obispo is a lovely city just minutes north. and Hearst Castle is less than an hour's drive North. Conveniently situated off the 101 freeway, a nice retreat from the big city.

Top guest favorite
A large outdoor patio area features a covered gazebo with seating and a paved surface. The surrounding landscape includes greenery and distant hills, providing a serene backdrop. The space is designed for relaxation and outdoor gatherings.
Home in Arroyo Grande
5 out of 5 average rating, 142 reviews

Hillside view with hot tub too

This house is the 2nd home on the property (main home is also STR). Located at the top of a private driveway with a beautiful view of the hills. Fully stocked kitchen with fridg/freezer, dishwasher, oven, 5 burner stove, microwave, ice maker, osmosis system, fully automatic espresso maker. 65” QLED TVs in living room and bedrooms. Patio furniture wiith covered gazebo, gas BBQ, pellet smoker/BBQ, patio heaters, fire table. Hot tub with gazebo accommodates 6. EV/Tesla charger in garage.

Guest favorite
The spacious backyard is showcased, featuring a newly installed turf area and a sports court for activities. A covered patio is visible, providing shaded seating, and the home's modern design blends with surrounding greenery. Solar panels are installed on the roof.
Home in Nipomo
4.97 out of 5 average rating, 103 reviews

Gateway to SLO County with Pickleball & Game Room

Family fun awaits at this 4500 sq feet home base to explore everything that San Luis County has to offer. Originally a log home, the home has been tastefully updated throughout the years and has a spacious open layout. There are 4 bedrooms, 3 bathrooms, a theater room, a game room and covered patio. There's something for everyone in the backyard with sports court, fire pit and bocce ball. Walk 2 minutes to 140 acre Nipomo Regional Park with new skate park & tennis and basketball courts.

Guest favorite
A modern living area features a large, flat-screen TV against a white wall. A surfboard is mounted beside a fireplace, and a round glass-top coffee table is set on a blue-patterned area rug. Natural light filters through sheer curtains.
Home in Oceano
4.95 out of 5 average rating, 164 reviews

Casa Del Mar

Enjoy a little getaway in this cottage by the beach. It’s cozy and simple with all the features of comfort. Walking to the beach is a just a short stroll down a windy little road filled with cool beach vibes. Cross a little wooden bridge and walk down a block or two and you are right in front of the Oceano dunes. Plan a bonfire and make s’mores on the beach. Or better yet, stay at the little cottage, grab a bottle of wine and enjoy a fire pit right outside your bedroom door.

Top guest favorite
A living area is shown with a sectional sofa arranged around a coffee table. Large windows provide natural light and offer views of the outdoor space. A clock is mounted on the wall, accompanied by decorative accents, while a door leads to the outdoor patio.
Home in Nipomo
4.97 out of 5 average rating, 107 reviews

Pleasant hills, king suite, EV Charger

Come relax and enjoy our peaceful home and outdoor spaces. We are located halfway between Los Angeles and San Francisco. Here you can experience the beautiful Central Coast including wineries, Beaches, Cal Poly and golf courses. We are located in a quiet neighborhood adjacent to an organic blackberry farm. Easy access to the 101 Freeway, where you can easily visit Santa Barbara or Paso Robles wine regions. Our home is FULLY Air Conditioned for your comfort.

Guest favorite
A light and airy kitchen features a wooden dining table surrounded by curved-backed chairs. A vintage-style refrigerator and stove are visible, complemented by a pendant light hanging above. Natural light enhances the warm wooden tones of the cabinetry and flooring, creating a welcoming cooking space.
Home in Los Alamos
4.87 out of 5 average rating, 357 reviews

Wine cellar House

Welcome to Bodega House, a restored 1920s farmhouse in the center of Los Alamos. The home features a serene queen bedroom and a separate lounge space, along with a sleeper sofa in the living area. Thoughtfully designed for two adults, the house can also comfortably host one to two children on the sleeper sofa. It’s an ideal setting for couples or small families seeking the ease and privacy of a home while being just steps away from the best of Los Alamos.

Guest favorite
A spacious living area features a leather sofa positioned beside a wooden coffee table. A dining set accommodates four, with a view of the modern kitchen in the background. Natural light enters through a back door, and a decorative rug enhances the warm ambiance.
Home in Oceano
4.88 out of 5 average rating, 110 reviews

Cozy Oceano Beach Retreat

Enjoy this recently renovated space located just a couple minutes drive to the beach. Home features a well-equipped kitchen, washer and dryer, high speed Wi-Fi and Smart TV, fully-enclosed side yard with BBQ and outdoor dining, ample parking for cars and a trailer, beach towels, beach toys and board games. There is a great coffee shop, grocery store, multiple restaurants and a new park that is close to completion, all walking distance away. No cats please.

Guest favorite
A bright and airy living space features a large window allowing natural light to fill the area. The room includes a cozy seating arrangement with a gray sofa, a wooden dining table with chairs, and decorative wall baskets. A kitchenette is visible in the background.
Home in San Luis Obispo
4.96 out of 5 average rating, 347 reviews

Wine Country Hilltop Retreat

Kick back and relax in this calm, stylish space with spectacular Edna Valley views. Read a book on your hillside patio and see buffalo and longhorns grazing in neighboring fields. After an incredible sunset, unwind by your firepit at night under a sky full of stars. This private country escape is also at the center of it all - 15 minutes to beaches & Cal Poly, 5 minutes to airport & 20+ wineries/tasting rooms, 10 minutes to beautiful downtown SLO.

Guest favorite
A bright living room is presented with natural light streaming through a window. Two comfortable chairs with soft throw blankets face a modern TV mounted on a pale wall. Decorative plants enhance the space, complemented by a wooden coffee table and light hardwood flooring.
Home in Arroyo Grande
4.93 out of 5 average rating, 228 reviews

Mid-century home in the heart of Arroyo Grande.

Welcome to the Eman House! I can't wait to host you at the 1950's mid century in Arroyo Grande, CA. Enjoy the beautiful remodeled kitchen, private backyard and patio, and two cozy bedrooms while soaking up the best of the central coast. Just a 10 minute walk to the historic Arroyo Grande village, a 5 minute drive to the beaches of Grover, and tucked away in one of Arroyo Grande's most peaceful cul-de-sacs.

Top guest favorite
A contemporary home is highlighted with expansive glass doors, allowing views of the surrounding landscape. A wooden dining table is shown, adorned with a sunflower. The deck extends along the residence, featuring comfortable seating areas.
Home in San Luis Obispo
4.95 out of 5 average rating, 125 reviews

Sanctuary on Sunset Ridge ~ Panoramic Ocean Views

Enjoy extraordinary VIEWS, PEACE, and PRIVACY just 15 minutes from downtown and beaches. Within 10-15 minutes: Hiking, Biking, SUP, Kayaking, Surfing, Wine Tasting, Great Restaurants, etc., etc. We are good-dog friendly. 3-night minimum stay. We have 2 ensuite King bedrooms - the 2nd has a loft with a double bed. Check us out on Insta: @sanctuaryonsunsetridge

Superhost
A spacious studio is presented with warm wood flooring and ample natural light from multiple windows. A queen bed is positioned beside a wooden table with chairs. An acoustic guitar leans against the wall, and a TV is mounted on a shelf nearby.
Home in San Luis Obispo
4.8 out of 5 average rating, 963 reviews

Spacious Slo Studio: AirBnB Dream

Solo or couple travelers this place is for you and what Air BNB was originally all about. Unique, friendly space that has taken on energy from all the travelers. Check in 3pm. Peep reviews, take it from patrons! BUSINESS LICENSE #: Zero Zero Zero One Six One Zero Eight Two Zero One Nine

Popular amenities for Guadalupe house rentals