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Vacation rentals in Guadalupe

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Guadalupe

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
An open living area is observed, featuring a futon couch, a dining table, and a television. A neatly arranged kitchenette is equipped with essential appliances, and a spacious bed is seen in the corner. Ample natural light enters through two windows.
Loft in Nipomo
4.94 out of 5 average rating, 873 reviews

Upstairs Guest Loft~EV Charge/Non-smoking/Pet-free

Private upstairs loft includes kitchenette, full bathroom, deck, and separate entrance. Grizzl-E Classic 40A EV Level 2 charger (Type 1/SAE J1772) with NEMA 14-50 and 6-50 plugs. Non-smoking, pet-free property. In the heart of CA's Central Coast between Los Angeles and San Francisco. Only 2 miles off Highway 101. Close to Pismo Beach, wineries, and golf at Monarch Dunes, Black Lake, and Cypress Ridge courses. Easy access for road trips, weekend getaways, and relaxing stays year-round. No AC.

Guest favorite
A modern living area features a cozy gray couch with decorative cushions, accompanied by a small circular table. Framed artwork adorns the white walls, and natural light brightens the space. A bar with two stools is visible, leading into a kitchen area.
Tiny home in Guadalupe
4.85 out of 5 average rating, 65 reviews

Cozy Tiny House Near The Beach

Consider this studio your home away from home while you visit the BEAUTIFUL Central Coast. This cool and pleasant space features 1 queen bed in the bedroom and a cozy living room with a couch that can sleep an additional guest(s). The Living room and bedroom are equipped with 50-inch TV' connected to the Wi-Fi for YouTube etc. Enjoy the convenience of a shower, hair dryer, iron and Wi-Fi during your stay. The unit you will be staying in is equipped with a full kitchen. Dining table/Island for 2.

Guest favorite
A spacious kitchen area features rich wooden cabinetry and a large gas range beneath a sleek exhaust hood. A mosaic tile backsplash adds texture, while natural light streams in through nearby windows, illuminating the granite countertops and various kitchen appliances.
Home in Arroyo Grande
4.9 out of 5 average rating, 173 reviews

Beautiful Country Home

Bring your family and friends to this beautiful, country Home just ten minutes from the beach. Rancho de la Cabeza is a peaceful, rustic ranch nestled between world class wineries, orchards, farms, golf courses, and the amazing beaches on the Central Coast! Are you looking to host a larger group? We have a smaller house on the same property. Both houses combined can sleep 18 people. Up to two dogs are allowed. $25 per pet fee. Smaller house: airbnb.com/h/central-coast-peaceful-haven

Top guest favorite
A cozy studio space features a spacious bed draped with a light canopy, complemented by soft linens. Natural light floods in through two windows, while a comfortable seating area with decorative pillows and a side table adds to the inviting ambiance.
Guest suite in Arroyo Grande
4.92 out of 5 average rating, 600 reviews

Cozy beach-themed studio with patio & jacuzzi

Relaxing, cozy beach-themed retreat designed for beauty & comfort. Private patio with bbq. Beautiful and relaxing jacuzzi oasis on property, available for one-hour use during each night of your stay. As 26-time Superhosts we have provided everything you may need for a great stay. The space is sparkling clean & offers the softest of linens, blackout curtains, extra pillows and soft blankets. Decorated with colors and decor of the ocean, we are sure you will feel all your worries drift away.

Guest favorite
A vibrant backyard playground features a converted lifeguard tower, providing a unique play area above. Below, a ball pit filled with blue balls awaits playtime, while bubbles drift through the air. The space is surrounded by green turf, enhancing the playful atmosphere.
Home in Arroyo Grande
4.97 out of 5 average rating, 109 reviews

OMG Playground, close to Beach, Family Fun

Relax near the coast at this Nautical Themed retreat! This peaceful home is in a conveniently located neighborhood. It's an updated 3 bedroom, 2 bath home, with modern features. The gem of this property is the backyard/ playground where your family will enjoy hours of fun. Backyard includes a converted Lifeguard Tower/ Treehouse, a Lighthouse Play Fort, Ball Pit, Trampoline, & Sand Box. The home is approx. 2 miles to Pismo State Beach and 2 blocks to shopping such as Starbuck's & Aldi.

Superhost
A modern living room features a dark blue sectional sofa accompanied by two light-colored armchairs. A large television is mounted on the wall opposite the seating area. Natural light enters through a window adorned with white blinds, and decorative lamps provide additional illumination.
Guesthouse in Santa Maria
4.83 out of 5 average rating, 102 reviews

Modern Guest House, 20 Min. Pismo Beach & Wineries

Welcome to our beautiful 2-bedroom, 1-bathroom guest house in the heart of Santa Maria! Nestled in a safe residential neighborhood, our brand new construction guest house is the perfect retreat for families and friends looking to explore the local wineries and vineyards or simply enjoy some beach days. The guest house offers a prime location, minutes away from the 101 freeway, making it easily accessible for our guests. Book your stay with us today and let us exceed your expectations!

Top guest favorite
A spacious living area features a large sectional sofa in dark leather, situated near multiple windows allowing natural light. A wooden coffee table is placed at the center, accompanied by decorative items. A flat-screen TV is mounted on the wall, adding to the entertainment space.
Guesthouse in Santa Maria
4.97 out of 5 average rating, 158 reviews

Private top floor spacious 1 bedroom retreat

Forget your worries in this spacious and serene space. Following CDC guidelines, we make sure your stay is a safe & enjoyable one. Equipped with a gas range stove, microwave, and washer/dryer. Relax in a full size tub, walk-in closet & plenty of space to store your items & gear. Enjoy hiking, biking & disk golf at near by Waller Park! Private entrance & exit. Please read our rules below before booking: 2 guests max 1 car parking No Parties No Smoking No Pets Additional fees may apply

Guest favorite
Home in Santa Maria
5.0 out of 5 average rating, 5 reviews

Pet-Friendly 5 bdrm Home w/ Gym & Large Backyard

Welcome to Casita Santa Maria, your spacious home away from home in North Santa Maria! This expansive 5-bedroom, 2.5-bathroom home has all the space and comfort you need. While our home is a well-loved property with plenty of character, it has been fully refreshed with brand-new furnishings, plush mattresses, and crisp linens. Located in a safe, quiet residential neighborhood just 5 minutes off the freeway, so you perfectly positioned to explore all the Central Coast has to offer.

Guest favorite
A wooden walkway leads through lush greenery, creating a natural archway. The bright sunlight filters through the leaves, illuminating the path. At the end of the walkway, a glimpse of the main house is visible, framed by vibrant plants.
Farm stay in Nipomo
4.88 out of 5 average rating, 609 reviews

Central coast paradise with forever views!

Large spacious private apt on a rustic, gorgeous property. Television High speed internet, pick fresh fruit, and lovely places to sit and relax. This beautiful place is an experience, to enjoy. Fridge, microwave, stove, oven, tea kettle and Keurig coffee maker. Enjoy the beautiful sunsets from the viewing deck or hot tub. Koi pond, chicken coop and free roam peacocks. Close to beaches, restaurants, wineries, wedding sites. Children and pets welcome.

Guest favorite
Home in Santa Maria
4.95 out of 5 average rating, 64 reviews

Home, comfortable to rest and relax. Welcome

Forget your worries in this spacious and serene space. In a quiet neighborhood where you can relax with your whole family, easy to find, near entrances and exits for the Freeway, very close to the shops where you can do your shopping easily. Everything is centrally located. No drugs are allowed in this home. If you break the rules, you will be immediately evicted from this home. If you meet the requirements. Welcome, thank you, and have a nice day!

Top guest favorite
A well-appointed sleeping area features a spacious bed dressed in a light-colored patterned coverlet. Stylish decorative pillows are arranged neatly at the head of the bed. A round table with a single chair sits nearby, surrounded by floral drapes that frame the window.
Guesthouse in Santa Maria
4.99 out of 5 average rating, 1749 reviews

French Country Casita - Breakfast Included

This stand-alone casita sits in the privacy of our rear yard and has a separate entrance. We are three minutes from highway 101 in the newer La Ventana community. Surrounded by beautiful mountain views on the Central Coast and close to many flourishing wineries, this residence is 20 minutes south of Pismo Beach, 30 minutes from San Luis Obispo, one hour north of Santa Barbara, close to the beautiful Danish city of Solvang and Santa Ynez.

Guest favorite
The exterior of a charming yellow cottage is presented, framed by a large oak tree and a rainbow overhead. Colorful flowers and plants adorn the pathway leading to the entrance, while a white pergola and outdoor seating are visible near the cottage.
Guesthouse in Arroyo Grande
4.96 out of 5 average rating, 196 reviews

Cottage at Lavender Oaks Farm

The Cottage at Lavender Oaks Farm is a wonderful peaceful guest house on a 5 acre lot. You’ll find a 780 sq.Ft indoor space with a private deck, giant oak trees and a beautiful view of the garden outside. The sunny open floor plan has a queen-sized bed, a couch, 2 loveseats a dining area and kitchen. The Cottage accommodates two adults. I will accept pets on a case-by-case basis.

Popular amenities for Guadalupe vacation rentals