Vacation rentals in Guadalupe

Guest suite in Santa Maria

A well-appointed bathroom features marble-topped vanity with a sleek faucet and mirror above. Soft white towels are hung on a towel bar, providing a practical touch. The wall is elegantly tiled in a herringbone pattern, complemented by warm lighting for an inviting ambiance.

4.87 out of 5 average rating, 781 reviews

Estate Guest Home—Upstairs, EV Charger on site

Chic exclusive private guest home with Kitchenette & Full bathroom in the heart of wine country.Home is upstairs above a 4 car garage attached to an Estate Home (No Shared walls).The Estate homes kitchen windows are adjacent to the guest home windows.When all the windows are open you may hear me in my kitchen as I am cooking or baking. One mile off the 101. Close to VAFB (20 mins), 1 hr to Santa Barbara.Orcutt is full of wine tasting rooms and restaurants.Orcutt is small & closes about 9 pm.

Apartment in Arroyo Grande

A spacious living area is showcased, featuring a modern kitchen area with stainless steel appliances. A dining table is surrounded by colorful chairs. The room is well-lit by natural light from large windows and a door leading to an outdoor patio. A television is mounted on the wall.

4.91 out of 5 average rating, 469 reviews

Central Coast Living

New two bedroom apartment Home with a full kitchen, living room, and patio. This clean / modern apartment is based in a semi-rural neighborhood located right off historic Hwy 1. Located slightly on the OUTSKIRTS for a more peaceful stay, this home is only a 10 minute drive from the beach, Central Arroyo Grande, the Oceano Dunes, wineries, hiking and biking trails, and farmers markets. 15 minutes from Pismo Beach and 20 minutes from San Luis Obispo. 5 minutes from 2 golf courses. PETS WELCOME.

4.94 out of 5 average rating, 815 reviews

Loft in Nipomo

Upstairs Guest Loft~EV Charge/Non-smoking/Pet-free

EV level 2 charging available. Non-smoking listing & pet-free. Upstairs guest loft with kitchen and bathroom, outdoor deck with private entrance. Located in the heart of the Central Coast-half way between Los Angeles and San Francisco. Escape the city to experience the central coast and all it has to offer ~ golf, beach, wineries, hiking and biking just minutes away. We are located only 2 miles off the 101 Freeway which makes us very convenient when traveling up or down the California coast.

4.92 out of 5 average rating, 623 reviews

Cottage in Arroyo Grande

The Ganja Getaway

WE CATER TO THE 420 FRIENDLY CROWD! Take a trip back in time and experience the 1970s style California cannabis farm! Chill out, play some old school vinyl records, and enjoy that sweet sweet California ganja! This was a medical cannabis farm prior to legalization. A blast from the past! The halcyon days of analog music, groovy style and Rock and Roll rebellion. Cool vibes and free beautiful human beings. Pet friendly but please notify me beforehand. This is an off grid antique farmhouse.

Superhost

An outdoor patio area is configured around a circular fire pit, with stone seating and wooden benches. The vintage camper can be seen in the background, framed by gentle hills and greenery. String lights hang overhead, creating a cozy outdoor gathering space.

Camper/RV in Lompoc

4.77 out of 5 average rating, 445 reviews

Farmstay in Vintage Remodeled Camper.

Enjoy the peaceful countryside in a charming 1964 Little Dipper vintage camper tucked away in a small canyon on a 40-acre working farm. The camper is refurbished with lovely aromatic cedar woodwork, a handmade dining table and comfortable queen bed. Lots of windows and colors make for an airy and bright space. It is powered entirely with solar for LED lighting, colorful accent lights, and outlets. Disconnect and enjoy the campfire, stars, farm animals, and fresh air. Only 10 min from town.

Guesthouse in Santa Maria

An outdoor porch area features a wooden deck with a round table surrounded by four chairs. Two additional chairs are placed to one side, ideal for relaxing. A vibrant umbrella offers shade, while a welcome mat adds a homey touch at the entrance.

4.96 out of 5 average rating, 114 reviews

Private top floor spacious 1 bedroom retreat

Forget your worries in this spacious and serene space. Following CDC guidelines, we make sure your stay is a safe & enjoyable one. Equipped with a gas range stove, microwave, and washer/dryer. Relax in a full size tub, walk-in closet & plenty of space to store your items & gear. Enjoy hiking, biking & disk golf at near by Waller Park! Private entrance & exit. Please read our rules below before booking: 2 guests max 1 car parking No Parties No Smoking No Pets Additional fees may apply

Superhost

A spacious living area is highlighted by a tan sectional sofa adorned with colorful throw pillows. A modern fireplace is situated against a textured wall, while a flat-screen TV is mounted on an adjacent wall. Soft lighting and decorative plants contribute to a welcoming ambiance.

Home in Santa Maria

4.74 out of 5 average rating, 113 reviews

*Casa Paloma* with sauna & jacuzzi

Whether traveling for work or pleasure, Casa Paloma will welcome you with her spaciousness and modern eclectic décor. Please enjoy our sauna, hot tub, workspace, and close proximity to Old Town Orcutt. Local restaurants & wine tasting a .5 mile walk away! 1 Cal King, 3 queens & 1 twin bed. Tesla charger Safe neighborhood Dogs welcome, large fenced yard Bikes upon request RO drinking water 805 BBQ Workspace & printer Refurbished, modern home Hotel linens Wine tasting Water softener

Camper/RV in Arroyo Grande

A decorative sign stating 'I love you to the beach and back' is positioned on a smooth countertop, surrounded by various seashells. The natural textures of the shells contrast with the solid color of the sign, offering a coastal vibe.

4.92 out of 5 average rating, 279 reviews

Glamping on the Central Coast- (fully sanitized)!

As 13-time SuperHosts-we welcome you to the Central Coast! Clean, comfortable coastal glamping in the countryside. Enjoy the Central Coast at a low price but with plenty of space in this 29 foot-long RV/trailer home. Country living neighborhood with plenty of eucalyptus trees, birds and various other wildlife nearby. Hosts are on the same property about 30 yards away and can make sure you enjoy your stay and answer any questions you might have but make sure to respect your privacy.

Guesthouse in Santa Maria

A modern bathroom features a glass-enclosed shower with a rainfall showerhead. Textured stone tiles in neutral tones adorn the walls and floor. A sleek vanity includes a vessel sink and wooden cabinetry, with natural light filtering through a nearby window.

4.99 out of 5 average rating, 1,591 reviews

French Country Casita - Breakfast Included

This stand-alone casita sits in the privacy of our rear yard and has a separate entrance. We are three minutes from highway 101 in the newer La Ventana community. Surrounded by beautiful mountain views on the Central Coast and close to many flourishing wineries, this residence is 20 minutes south of Pismo Beach, 30 minutes from San Luis Obispo, one hour north of Santa Barbara, close to the beautiful Danish city of Solvang and Santa Ynez.

Guesthouse in Arroyo Grande

A garden view showcases a white pergola shaded by vibrant greenery. Underneath, a small dining table and chairs are positioned on a wooden deck. Surrounding plants include succulents and colorful flowers, providing a serene landscape that invites relaxation.

4.98 out of 5 average rating, 164 reviews

Cottage at Lavender Oaks Farm

The Cottage at Lavender Oaks Farm is a wonderful peaceful guest house on a 5 acre lot. You’ll find a 780 sq.Ft indoor space with a private deck, giant oak trees and a beautiful view of the garden outside. The sunny open floor plan has a queen-sized bed, a couch, 2 loveseats a dining area and kitchen. The Cottage accommodates two adults. I will accept pets on a case-by-case basis.

Superhost

A staircase with warm-toned carpeting leads downwards, framed by a black wrought iron railing featuring decorative detailing. A view of a hallway is visible in the background, with doors leading to various rooms, creating a welcoming entryway to the upper floor.

Home in Guadalupe

4.84 out of 5 average rating, 209 reviews

Beach home near golf, wineries, dunes & Vandenburg

This Pasadera home has three bedrooms two and a half bathrooms with a loft which has a fold out couch. The downstairs couch will sleep 2 more if needed so 9 people will fit. It’s just a few miles away from Trilogy and Blacklake golf course, the beach, shopping , golf courses and many wineries! It’s a perfect beach community. About 20 minutes to Vandenburg Air Force base.

Guesthouse in Santa Maria

4.88 out of 5 average rating, 235 reviews

Cottge On The Crt: Hike, Winery, Beaches 20 min

Nestled in an upscale private neighborhood you'll find your own personal space on the central coast. Enjoy hikes, dining and wineries in Orcutt or travel the short distances to San Luis Obispo, Pismo/Avila Beaches, Solvang/Santa Ynez, Santa Barbara and Lompoc (VSFB) to enjoy more of our beautiful coastline where the weather is almost always perfect

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Other great vacation rentals in Guadalupe

A wooden console table is displayed against a light grey wall, showcasing a colorful collection of architectural models. Above the table, a world map in muted tones is mounted. A tall plant in a decorative pot adds greenery to the corner, and a television is mounted nearby.

4.93 out of 5 average rating, 215 reviews

King’s Getaway

JosephRating, 5 stars2 weeks ago

I needed a last minute place due to a cancellation and Christian came through. He was welcoming and cool. Had a great night sleep, went for a lil walk in the morning around the neighbourhood and took off. :)

Private room in Arroyo Grande

4.95 out of 5 average rating, 436 reviews

Quiet Country Cottage

KatieRating, 5 stars2 weeks ago

Cozy and peaceful cottage! Nestled in the hills but close enough to be a quick drive to everything the SLO area has to offer. The property is beautiful and very serene. We saw a mama deer and her baby right outside our window. The hosts provided lots of thoughtful amenities, and you can tell a lot of love and attention is given to this cottage. We really enjoyed our stay and hope to come back someday.

A small bistro set featuring a round turquoise table and two folding chairs is positioned on a concrete patio. Green plants are arranged on the table, and a stone wall with various shrubs serves as a backdrop, enhancing the outdoor space.

4.98 out of 5 average rating, 535 reviews

Quiet Santa Maria home perfect to rest & relax

LindaRating, 5 stars2 days ago

This was our first Airbnb experience and I’m sure we could never have a better one. Mary and her husband treated us like family and went above and beyond our expectations. We loved the fresh coffee, strawberries and pastries in the morning and the interesting conversations. Thank you Mary, we hope to meet again.

A small dog sits comfortably on a red and black plaid blanket atop a textured sofa. The dog has a shiny coat, perked ears, and is sticking out its tongue playfully. A soft, light-colored toy sits nearby on the blanket.

4.85 out of 5 average rating, 391 reviews

Cosy & Close to Everything.

ErinRating, 5 stars1 week ago

Stayed less than 12 hours on a roadtrip, but it was a peaceful stopping point. Clean, accurate, and Gina provided everything you would need for a pleasant stay.

4.87 out of 5 average rating, 23 reviews

Home in Guadalupe

GORGEOUS HOME, BEACH, BBQ & WINE🌊🌴🍷🥂 RELAX & PLAY

KarlaRating, 5 stars2 days ago

Scott and Rae’s place was absolutely amazing. Everything was great and they made everything super easy for us. We loved how they had a coffee machine in the upstairs bathroom which was perfect for getting ready in the early mornings. The house is quiet and peaceful. Wonderfully house and amazing hosts. We hope to be back.

4.96 out of 5 average rating, 274 reviews

Charming Cottage at Hummingbird Gardens

RebeccaRating, 5 stars1 week ago

Vicky is a lovely person and a warm and inviting host providing a comfortable space where you’re sure to get a good nights rest. I love staying with Vicky when I’m in the area- she’s lovely to talk to and her home is cozy and inviting with a wonderful walkway of potted plants that I love admiring out front. She has plenty of recommendations for things to do in along the central coast with great local recs for food. Although I arrived late, check in and parking were a breeze with lights on out back, in the hallway, and my room for easy navigation.

4.9 out of 5 average rating, 503 reviews

A cozy corner displays a collection of potted plants and decorative items. A woven globe and a lantern provide soft lighting, while a serene landscape painting hangs on the wall. The green walls create a harmonious backdrop for the arrangement.

Private room in Nipomo

The Sol Shack

CheyenneRating, 5 stars3 weeks ago

My quick stay at Loris was everything I needed. COMFY bed & linens, nice warm shower, beautiful nature and the best part? The Yoga Class she taught in the morning. I was so zen’d out being there. Don’t hesitate- if her place is open- book it!