House vacation rentals in Edisto River

Find and book unique houses on Airbnb

Top-rated house rentals in Edisto River

Guests agree: these houses are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Guest favorite

The exterior of the home features a white façade with yellow shutters and a bright door. The well-maintained yard is surrounded by trees, offering a serene setting. A concrete driveway provides clear access to the entrance, with ample green space visible in the foreground.

Home in Summerville

4.94 out of 5 average rating, 139 reviews

Near Nexton w/firepit, foosball, games & fast WiFi

This home is close to everything! Super clean! Including a firepit w/ mood lights, games, corn toss, TVs in each BR, and a well-equipped kitchen. 1mi to Nexton Square and many restaurants 4 mi to Historic Summerville 23 mi to Historic Charleston 34mi to Folly Beach and Isle Of Palms 8 mi. to Wannamaker Park (Waterpark) Great for business travelers or hospital workers due to close proximity to Trident Hospital, Roper Hospital, Charleston International Airport, Boeing, Volvo, Bosch, and Mercedes.

Guest favorite

A spacious living area features a high ceiling and ceiling fan. A comfortable sofa and a recliner are arranged around a coffee table. Natural light fills the room through multiple windows. A flat-screen TV is mounted on the wall, displaying a serene beach scene.

Home in Goose Creek

4.94 out of 5 average rating, 105 reviews

Pet friendly 3-bedroom, screened patio, EV Charger

Spacious 3-bedroom 2-bath home just a 20-minute drive to Charleston and short drive to local beaches. Also 10-minute drive from the Naval Weapons Station. This home is family/pet friendly including a covered patio, ample open space and all basic amenities. Even an In-unit washer and dryer provided for those who need it! Please BYOP: Bring Your Own Passwords! Connect to your streaming services on our smart TV! We believe every guest deserves a 5-star experience and we strive to ensure this!

Top guest favorite

The kitchen features modern white cabinetry, a spacious granite countertop, and stainless steel appliances. A decorative arrangement of dried florals is placed on the counter, complementing the soft blue walls. Two upholstered stools provide casual seating at the bar area.

Home in North Charleston

4.98 out of 5 average rating, 110 reviews

Park Circle Escape- Close to DT, Beaches & Airport

This centrally-located cottage is near it all! From the front door you are only 15 mins to DT Charleston, a mile to Park Circle's trendy restaurants & bars, 25 mins to the beach & 10 mins to the airport. Both bedrooms have new king beds, blackout curtains & Smart TV's. The living sleeps additional guests with its sleeper sofa, blackout curtains & TV. Traveling with kids? This home has a private fenced yard & is stocked with a pack&play, highchair, baby bath, sound machines, toys, books & games.

Top guest favorite

The master suite features a spacious bed with a vibrant orange coverlet, complemented by a cozy chair and a desk with a monitor. A large flat-screen television is mounted on the wall, and natural light enters from the nearby doorway leading to the bathroom.

Home in Beaufort

4.99 out of 5 average rating, 150 reviews

Sand in My Boots, mins. to MCRD PI W/Kids SwingSet

Sand In My Boots is located in close proximity to Marine Corps Recruit Depot Parris Island. This exquisite residence offers an ideal accommodation choice for individuals attending Marine graduations, seeking a vacation retreat, or on business trips. For a relaxing beach getaway, Hunting Island (National Park) is a quick drive and voted one of the best in SC. This house is 3 minutes away from a great Golf Course. With a huge pond just a 2 minute walk from the house where you can fish and relax.

Top guest favorite

The image captures a serene landscape where sunlight filters through trees, casting long shadows on the grassy ground. Spanish moss drapes from branches, creating a tranquil and inviting scene alongside the waterfront.

Home in North Charleston

4.98 out of 5 average rating, 110 reviews

Waterfront Nature’s Retreat Cottage 2Bd/2B

Take it easy at this unique & tranquil waterfront getaway where you will be able to enjoy the stunning views of the Ashley river and beautiful sunsets over Magnolia Gardens. The Cottage is located on 1.5 acres on private property Whether you are here for work or play, this property is centrally located: Min from airport, outlets, breweries, restaurants, I-26, 526, Bosch, Boeing, 20 min from DT Charleston 30 min from the beach. NO PARTIES NO SMOCKING NO PET NO SWIMMING NO DOCK ACCESS 4 PERS

Guest favorite

A charming single-family home is surrounded by a large, fenced yard, featuring well-maintained green grass. The house showcases a light-colored exterior with blue shutters and a two-car garage. Trees provide some shade, enhancing the inviting exterior space.

Home in Summerville

4.9 out of 5 average rating, 150 reviews

Summerville home~ground floor bedroom~25min to CHS

💘 Fall in Love at The Paramour! This Summerville stay has everything you need for a stress-free getaway: ✨ Close to Nexton~Taco Boy~Halls Chop House 🧼 $0 cleaning fee + professionally cleaned 🧳 Free early luggage drop ⏰ Free early check-in (when available) 🌳 HUGE fenced-in yard 🏊 Pool access (available for a fee) 🌴 30 min to Downtown CHS & beaches like Sullivan’s Island 🔐 VERY safe area 🧺 No chores at checkout—just pack and go! ✅ Cancel up to 5 days before arrival for a full refund!

Guest favorite

Home in Edisto Island

4.97 out of 5 average rating, 105 reviews

Marshfront Villa In The Trees - Near Beach & Bay

"The most unique and relaxing place to enjoy the tranquility and experience of Edisto. We did not want to leave" - Sambo Nestled atop 360-degree marsh views, you'll be immersed in the exotic natural beauty and wildlife of the Edisto sea island. Hear the waves crashing at the beach from the front porch and watch the marsh tides rise and fall from your choice of the many porches. "Nature with luxury.. our group loved floating from the house out to the inlet for private beach days" - JP

Guest favorite

A bright and airy living room features two large, comfortable couches arranged around a wooden coffee table. Large windows allow natural light to fill the space, while light-colored curtains add a soft touch. A cozy fireplace is situated beneath a wall-mounted TV.

Home in Seabrook Island

4.95 out of 5 average rating, 145 reviews

Beautiful 2BD/2BA Seabrook Island Villa

Enjoy beach living in this beautiful two bedroom, two bath villa! Just 23 miles from downtown Charleston, Seabrook is a gated, 2200 acre resort community with multiple luxury amenities. This end unit villa overlooks the 15th fairway on Crooked Oaks golf course, and is just steps away from a private pool available only to residents and guests of Live Oak Villas. Beach and pool access, Seabrook Island Beach Club, and dining with spectacular views of the ocean, are located only a mile away.

Guest favorite

The exterior of the villa is shown, featuring a light-colored stucco façade contrasted by large windows. Surrounding landscaped areas include planters with vibrant greenery and flowers. A gravel pathway leads to the entrance, framed by the natural beauty of trees in the background.

Home in Summerville

4.92 out of 5 average rating, 114 reviews

Guest House/Villa

Enjoy your stay at this immaculately designed new build Villa. Located on a family property surrounded by 2 acres of trees, in a quiet rural neighborhood. Lots of privacy, peace and quiet, yet only 5 minutes from restaurants and stores. 15 minutes from Downtown Summerville, 40 minutes from Charleston and various coastal attractions. The villa is separate from main house and has no shared space other than the driveway. NO smoking, No pets. Laundry service available for long stays.

Guest favorite

A private saltwater pool is surrounded by a spacious patio, featuring lounge chairs and a backdrop of well-kept landscaping. The screened-in porch showcases outdoor seating and a pool table. Inside, a den offers additional recreational space, inviting relaxation and fun.

Home in Summerville

4.96 out of 5 average rating, 163 reviews

Pool | Screened Porch | Pool Table | Large Yard

Experience the best of Summerville in this stylish single-level retreat. Perfect for families and friends, it features cozy bedrooms, a private pool, a game-filled den, and a screened-in porch with a saltwater pool and pool table. Modern design and thoughtful details make this the ideal spot for a memorable stay. Farmer’s Market - 13 min drive Dorchester Museum - 13 min drive Azalea Park & Sculpture Garden - 14 min drive Book for a Memorable Summerville Getaway— Details Below!

Guest favorite

A bright living area features a soft beige sofa adorned with a patterned throw and decorative pillows. A large television is positioned on a wooden console. A light fixture hangs above a circular coffee table surrounded by two colorful armchairs, with plants and artwork adding to the decor.

Home in Charleston

4.99 out of 5 average rating, 198 reviews

Charleston Boho Bungalow ✨3 MILES FROM DOWNTOWN✨

Welcome to the Charleston Boho Bungalow! The coziest of stays. Summon all your boho vibes with this sleek and stylish space which includes an outdoor tub/shower! Here you will find relaxation amidst a vibrant city boasting the tastiest eats, beautiful beaches and an absolute overabundance of charm. Enjoy a 3 mile commute into downtown Charleston or a short drive to Folly Beach. Also a short 15 minute drive from the airport. Excited to host your experience! (OP2023-04138)

Guest favorite

A bright dining area features a round table surrounded by four light-colored chairs. Natural light illuminates the space through multiple windows, highlighting the warm tones of the wooden floor. The kitchen area, visible in the background, includes modern stainless appliances and a stylish backsplash.

Home in North Charleston

4.93 out of 5 average rating, 157 reviews

Newly remodeled Park Circle bungalow

This 2 bedroom home in the heart of Park Circle has just undergone a full renovation. It is conveniently located. 10-15 min drive to downtown Charleston. It is a short walk to all the Park Circle restaurants, breweries, parks, bars, and more. Holy City Brewery, Firefly Distillery, and Riverfront park are right by the house. To enjoy the beach head about 25-35 min to Sullivans Island, Isle of Palms or Folly Beach. Please note there is a train track behind backyard fence.