Guesthouse vacation rentals in Durham County
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Top-rated guesthouse rentals in Durham County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Durham County guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Raleigh
4.87 out of 5 average rating, 435 reviewsAdorable 1BR studio in Five Points
Jun 7 – 14
Guesthouse in Hillsborough
4.96 out of 5 average rating, 333 reviewsHummingbird Retreat
Jul 8 – 15
Guesthouse in Carrboro
4.85 out of 5 average rating, 411 reviewsGuest cottage close to downtown Carrboro
Jun 24 – Jul 1
Guesthouse in Chapel Hill
4.96 out of 5 average rating, 340 reviewsCozy Secluded Accessible West Wing
Jul 22 – 29
Guesthouse in Apex
4.92 out of 5 average rating, 348 reviewsCountry place close to all Triangle locations
Jul 23 – 30
Guesthouse in Cary
4.92 out of 5 average rating, 295 reviewsCentral to Everything, Renovated, Dog Friendly.
Aug 10 – 17
Guesthouse in Raleigh
4.98 out of 5 average rating, 891 reviewsWalk to downtown. Private stylish studio cottage.
Jan 5 – 12
Guesthouse in Durham
4.87 out of 5 average rating, 181 reviewsRockwood Oasis Studio BR Bath no kitchen
May 25 – Jun 1
Guest house rentals with a patio
Guesthouse in Raleigh
4.9 out of 5 average rating, 121 reviewsRetreat La Cabana
Nov 30 – Dec 7
Guesthouse in Raleigh
4.99 out of 5 average rating, 131 reviewsDowntown Private Oasis w/ Cal King
Sep 5 – 12
Guesthouse in Chapel Hill
4.9 out of 5 average rating, 51 reviewsThe cozy home
Jan 26 – Feb 2
Guesthouse in Raleigh
5.0 out of 5 average rating, 27 reviewsCarriage House Studio in Quiet Neighborhood
Sep 19 – 26
Guesthouse in Holly Springs
5.0 out of 5 average rating, 83 reviews"Wit's End" welcomes you! 2BR comfy guest house
Dec 26 – Jan 2
Guesthouse in Chapel Hill
4.81 out of 5 average rating, 31 reviewsGuesthouse + Access to Morgan Creek Trail
Feb 8 – 15
Guesthouse in Raleigh
4.99 out of 5 average rating, 82 reviewsNeighborhood Loft
Jan 16 – 23
Guesthouse in Raleigh
5.0 out of 5 average rating, 41 reviewsThe Nest: Private Downtown Guest House
May 26 – Jun 2
Guest house rentals with a washer and dryer
Guesthouse in Durham
5.0 out of 5 average rating, 5 reviewsPinky - A Cute Durham Camping Trailer
Sep 11 – 18
Guesthouse in Durham
4.83 out of 5 average rating, 36 reviewsProfessor's Cottage in Duke Park.
Jul 28 – Aug 4
Guesthouse in Durham
4.93 out of 5 average rating, 41 reviewsDuplex filled with natural light
Jan 19 – 26
Guesthouse in Durham
5.0 out of 5 average rating, 3 reviews* Private Garage * Studio Apartment * Pet Friendly
Aug 18 – 25
Guesthouse in Durham
5.0 out of 5 average rating, 15 reviews1 Bedroom Apartment Overlooking Duke Campus East
Nov 5 – 12
Guesthouse in Durham
4.97 out of 5 average rating, 35 reviewsDownUnder @DukePark Standing Desk Charming & Clean
Aug 31 – Sep 7
Guesthouse in Durham
4.95 out of 5 average rating, 43 reviewsBeautiful Alley House 2 Blocks to Duke + Downtown.
Mar 5 – 12
Guesthouse in Durham
4.94 out of 5 average rating, 87 reviewsSunny New Carriage House off Duke’s East Campus
May 9 – 14
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