
House vacation rentals in Santo Domingo de Guzman
Find and book unique houses on Airbnb
Top-rated house rentals in Santo Domingo de Guzman
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Santo Domingo de Guzman house rentals
House rentals with a pool

Steel-Loft - Whole house with sea-view terrace

PrivatePool - BBQ - Terrace - Excelent for Big Fam

Experience Ultimate Comfort | 4BR Home

Private Pool, Fast Wi-Fi, A/C, Near Zona Colonial

FIXIE Lofts: Elegant Colonial Villa with Pool

Casa Aló:Private house with jacuzzi in the Capital

Royal Villa with a swimming pool in Villa Mella SD Norte.

House located in the center of La capital
Weekly house rentals

Comfortable and Centrally Located with Elevator/Naco Lobby

Beautiful near the sea!

Large family residence

LJC Stay III

Colonial Treasure + Historic 2BR House+Terrace

House in Santo Domingo

Casa Baez

House in Prolongación Venezuela
Private house rentals

Stunning spacious home great location, 2 ensuites

8BR Old Town Colonial Villa w/ Pool for 20 Guests

Your perfect getaway in the Colonial Zone!

Graccie Hotel

luxurious house with pool free parking downtown

Lovely Relaxing home with parking

Naco apt Jacuzzi and gym

Newly Renovated 2bed in the Heart of the Capital.
Destinations to explore
- Beachfront rentals Distrito Nacional
- Rentals with a washer and dryer Distrito Nacional
- Rentals with a fire pit Distrito Nacional
- Waterfront rentals Distrito Nacional
- Loft rentals Distrito Nacional
- Pet-friendly rentals Distrito Nacional
- Rentals with pools Distrito Nacional
- Rentals with a sauna Distrito Nacional
- Villa rentals Distrito Nacional
- Rentals with a patio Distrito Nacional
- Rentals with a hot tub Distrito Nacional
- Serviced apartment rentals Distrito Nacional
- Hotel rentals Distrito Nacional
- Ski-in/ski-out rentals Distrito Nacional
- Family-friendly rentals Distrito Nacional
- Guesthouse rentals Distrito Nacional
- Rentals with outdoor seating Distrito Nacional
- Rentals with a fireplace Distrito Nacional
- Rentals with breakfast Distrito Nacional
- Apartment rentals Distrito Nacional
- Rentals with an accessible height bed Distrito Nacional
- Kid-friendly rentals Distrito Nacional
- Fitness-friendly rentals Distrito Nacional
- Rentals with beach access Distrito Nacional
- Rentals with lake access Distrito Nacional
- Rentals with an EV charger Distrito Nacional
- Smoking-friendly rentals Distrito Nacional
- Condo rentals Distrito Nacional
- Rentals with a home theater Distrito Nacional
- House rentals Dominican Republic
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom