House vacation rentals in Santo Domingo de Guzman

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Top-rated house rentals in Santo Domingo de Guzman

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Guest favorite

Home in Santo Domingo

4.96 out of 5 average rating, 47 reviews

Private Pool | Fast Wi-Fi+A/C+BBQ+Family friendly+

Relax with the whole family in this accommodation where tranquility is breathed. Enjoy the pool and the brick barbecue in the tranquility of the patio next to the garden, listening to the waterfall in this Private House located in Santo Domingo, the first city of America. 4 Bedrooms with 3 comfortable Queen beds, 1 Twin Bed, 1 Sofa Bed, Crib, Queen Inflatable Mattress, 4 bathrooms, outdoor shower, A / C throughout the house, Board Games, full kitchen, Washer and dryer, hot water, near malls +++

Mar 3 – 10

R2,269 ZAR per night

Guest favorite

Home in Santo Domingo

4.99 out of 5 average rating, 75 reviews

Casa Serena: cozy, modern, spacious and peaceful

Welcome to Casa Serena! A cozy, modern, and spacious house that exudes tranquility... perfect for trips with family or friends seeking a peaceful retreat. The ideal home for those looking to stay in a central area of Santo Domingo while also enjoying the benefits of a low-density residential neighborhood. With easy access, minimal traffic, high safety standards, serene surroundings, friendly neighbors, and a sense of peace, Casa Serena in the La Castellana urbanization is the perfect choice.

Sep 15 – 22

R2,620 ZAR per night

Guest favorite

Home in Santo Domingo

5.0 out of 5 average rating, 10 reviews

Steel-Loft - Whole house with sea-view terrace

Where historic walls meet modern steel - 3 individual, comfortable, 73F cooled loft-studios with king-size bed, a spacious bathroom, big shower, 3 small kitchenettes with microwave, fridge and freezer. Working area, fast wifi , TV and safe. Different spaces to relax, have meeting or enjoy barbecue. Loft 01 has an additional private patio with warm jacuzzi. Located in a quiet, but centric neighborhood, near seaside restaurants If you look just for one or two rooms: check: steel-lofts 01/ 02/ 03

Sep 9 – 16

R4,540 ZAR per night

Guest favorite

Home in Santo Domingo

4.92 out of 5 average rating, 12 reviews

Charming & central place to live

Spacious and peaceful accommodation with a central location and view. The modern penthouse of 167 sqm is in 3rd floor and consists of two large bedrooms with walking closet and closet, two toilets, a large living room and terrace, fireplace, small pool, air conditioner, etc. Private parking (outside too). Access to both shops, public transport and some exciting places in the surrounding area such as Malecón, Guibia beach, Plaza Juan Baron, direct and easy travel route to Alcazar de Colon.

Apr 6 – 13

R1,016 ZAR per night

Guest favorite

Home in Santo Domingo

4.96 out of 5 average rating, 175 reviews

Cozy Casita at the heart of Colonial Zone

Cozy 2 bedroom house with capacity for 4 people, located in the heart of the Colonial Zone in Santo Domingo within walking distance of all cultural and tourist attractions. It has 2 comfortable rooms and a study with sofa bed; 2 bathrooms, a nice living room, large dining room, equipped kitchen and a beautiful interior patio. Wonderful for vacations and cultural travel, ideal for couples, families, friends, and business travelers.

Nov 13 – 20

R1,626 ZAR per night

Guest favorite

Home in Miraflores

4.94 out of 5 average rating, 127 reviews

Cozy, central, and well-equipped place

We are located in a quiet, central sector of the city, with access to Avenues 27 de Febrero, Máximo Gómez, Jhon F. kenndy. Nearby are the Universidad Iberoamericana (Uníbe), Zambil shopping center, Torre Banco Popular Dominicano, as well as pharmacies and health centers. The apartment is located on the first floor, with independent access, parking and electric gate. Features cable system, WiFi with high speed, inverter.

Oct 7 – 14

R642 ZAR per night

Guest favorite

Home in Santo Domingo

4.86 out of 5 average rating, 37 reviews

Casa Grullon

A Glimpse into History: Transport yourself to another era with a stay at Casa Grullon. Our 2-bedroom, 1-bathroom oasis, dating back to the 1600s, offers a unique chance to experience colonial charm without sacrificing modern conveniences (like air-conditioning for example). Stay here and discover La Zona just by walking! No need for a car since everything is within walking distance (top restaurants are just 1 min away!)

Jun 29 – Jul 6

R1,823 ZAR per night

Guest favorite

Home in Santo Domingo

5.0 out of 5 average rating, 12 reviews

Bella Vista 3 Bedroom Apartment| Rooftop Pool| Gym

Luxurious 3-bedroom apartment in the heart of Bella Vista, Santo Domingo. Perfect for families or groups, offering modern amenities and stylish design. Prime location near shopping malls and high-end restaurants. A cozy living space, a fully-equipped kitchen, and thoughtful details ensure a comfortable stay. Experience Santo Domingo's best from this centrally located haven. Book now for an unforgettable vacation!

Nov 8 – 15

R2,965 ZAR per night

Guest favorite

Home in Santo Domingo

4.95 out of 5 average rating, 99 reviews

Charming Old City Corner House

This charming 2 bedroom corner house is located in the walled colonial city of Santo Domingo. It’s only a few steps away from historical attractions, museums, restaurants, coffee shops, bars, souvenir shops, bakeries, supermarket and lovely squares. The beautiful covered terrace, overlooking the rooftops of the old town with living area, hammock and BBQ is perfect for a relaxing afternoon or evening.

Jul 26 – Aug 2

R2,805 ZAR per night

Guest favorite

Home in Santo Domingo

4.87 out of 5 average rating, 271 reviews

Heart of the colonial zone, Billini 54

At the very heart of the most exclusive part of the colonial city where all the fun and interesting activities take place. This beautiful one-bedroom apartment is on the first floor of a small building next to the colonial gate 4D cinema, electric bike rentals, beer market, food markets, historical landmarks, exclusive boutiques, galleries, restaurants and bars.

Sep 3 – 10

R1,054 ZAR per night

Guest favorite

Home in Santo Domingo

4.94 out of 5 average rating, 32 reviews

Cozy & Beautiful City Center House with Jacuzzi

The House is located in " El Cacique", one of the safest areas in the city, with access to Malecón ( Caribbean Sea), supermarket and clinics 5 minutes walk, access to Mirador Sur park, and 15-20 minutes from the most prestigious shopping centers in the city. Located approximately 40 minutes from the airport and 14 minutes from Zona Colonial.

Sep 3 – 10

R3,020 ZAR per night

Superhost

Home in Santo Domingo

4.85 out of 5 average rating, 75 reviews

Casa RossAmor

Casa RossAmor. Two-level house located in downtown Colonial Zone, in Santo Domingo D.N 40 minutes from the airport. 6 bedrooms 4 bathrooms, living rooms, and dining room. Bar, pool, social area, air conditioning , heater, internet, inverter, TV with Neflix, horn with bluetooth. It is located in the same historic center of the city.

Oct 7 – 14

R12,726 ZAR per night