Vacation rentals in Des Moines County

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Top-rated vacation rentals in Des Moines County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite

Apartment in Burlington

5.0 out of 5 average rating, 238 reviews

Downtown Living

Greater Burlington is rich in history and full of exciting attractions such as the PZAZZ! Entertainment Complex, minor league baseball, and Starr's Cave Park. Known for Snake Alley, "The Crookedest Street in the World," Burlington delights all with many attractions, a lot of history, and a little magic. The unit is located one block from the Mississippi River. Walking distance to several restaurants and pubs. Iowa welcome center is in the Port of Burlington on the river just east of the unit.

Dec 9 – 16

R3,343 ZAR per night

Guest favorite

Home in Oquawka

4.89 out of 5 average rating, 19 reviews

Oquawka Cottage With River View

Reconnect with loved ones in this family-friendly place. Enjoy the comfortable living area, or kick back on the deck with a view of the Mississippi River. There's also a quaint front porch. Walking distance from local bar & grill. Quiet, safe neighborhood. The kitchen has all the amenities of home. Washer and dryer are located in one end of the bathroom. We are only a phone call away should you need anything. No matter if you're visiting family or here working we hope you enjoy your stay.

Jul 15 – 22

R2,073 ZAR per night

Guest favorite

Loft in Burlington

5.0 out of 5 average rating, 182 reviews

The Peacock Loft / Spacious Artistic Loft

Welcome to The Peacock Loft! This space is my full time photography studio that I also share on Airbnb! My love for design, color and visually beautiful details has spilled into every corner of this space. The loft is full of art, custom design, travel finds, creative literature, vintage decor and boho dreaminess. It's an old charming building with modern renovations and only a few blocks from nostalgic Downtown Burlington, Iowa. We have all the amenities you need and off street parking.

Jul 31 – Aug 7

R1,443 ZAR per night

Guest favorite

Home in West Burlington

4.86 out of 5 average rating, 49 reviews

Lovely Leffler Lodge - 2 BRM Sleeps 6

Bright and cozy pet friendly 2 bedroom, lower unit of a duplex on a beautiful corner lot in a quiet neighborhood. Perfect for traveling families with pets. Bedroom one has a queen bed, and bedroom two has a bunk-bed with full size futon on the bottom and twin on top. Convenient laundry room, large kitchen, dining room with workstation, and living room. Located one block from downtown West Burlington shops and restaurants and our local shopping mall and movie theater.

Feb 4 – 11

R1,948 ZAR per night

Guest favorite

Home in Burlington

4.99 out of 5 average rating, 149 reviews

Snake Alley Inn, a one-of-a-kind location.

Snake Alley Inn, a Victorian home nestled high on the hill on Burlington's famous Snake Alley. This 1894 landmark brick-paved street, was once recognized by Ripley's Believe It or Not as the Crookedest Street in the World. Built in 1860 this historic home is adorned with 3 bedrooms and 2 full baths. Located within walking distance to Burlington's dynamic downtown, where you'll find many shops, pubs and eateries.

Jan 28 – Feb 4

R3,423 ZAR per night

Guest favorite

Townhouse in Burlington

5.0 out of 5 average rating, 30 reviews

Comfy Corner North

Welcome to Comfy Corner North in downtown Burlington, Iowa. Enjoy your stay in our 1880 duplex that overlooks downtown. You are just a walk over the bridge from all the shops and restaurants on Jefferson St. and another block north to Burlington’s infamous Snake Alley - the crookedest road in America. Conveniently located close to downtown entertainment and all the Mississippi river front has to offer.

Sep 29 – Oct 6

R2,432 ZAR per night

Guest favorite

Home in Burlington

4.95 out of 5 average rating, 59 reviews

The Fleetwood Bungalow with Dreamy Porch

Welcome to The Fleetwood Inn! A charming, cozy one-bedroom bungalow in the heart of Burlington, Iowa. Right between our bustling business district and our nostalgic downtown, this little house has vast character. My favorite feature is all the original built-ins and beams. You will love the Western American inspiration and vintage finds, modern touches throughout, and dreamy details in every corner.

Jan 2 – 9

R1,245 ZAR per night

Guest favorite

Apartment in Burlington

4.98 out of 5 average rating, 91 reviews

Riverview Upstairs Apartment

Upper level duplex located near downtown Burlington. We are within walking distance from Dairy Queen and Jerry’s Main Lunch (our favorite breakfast!) Only 1.5 miles to downtown shopping, riverfront, entertainment and restaurants. Private balcony with river views, private laundry and pet waste stations. Set next to a large open lot for pets and outdoor activities.

Feb 4 – 11

R2,101 ZAR per night

Guest favorite

Loft in Burlington

5.0 out of 5 average rating, 38 reviews

The Brick House 100. Luxury Downtown Apt

Luxury 2 bedroom apartment. Renovated historic building with view of downtown, the Mississippi and the manor grounds. The downstairs apt will be available by May 5th. We have shared some upstairs photos. The layout will be very similar. Large master bedroom. Twin bunk bed room. Door to deck overlooking downtown.

Nov 5 – 12

R2,191 ZAR per night

Guest favorite

Townhouse in Burlington

4.93 out of 5 average rating, 15 reviews

Mosquito Park Condo

Have fun with the whole family at this stylish 1890 building. There's a park that overlooks the Mississippi. And for the musically inclined there is a piano! It's just a short walk downtown. Where there's lots of great restaurants and cool shops.

Nov 1 – 8

R1,642 ZAR per night

Superhost

Apartment in Burlington

4.93 out of 5 average rating, 14 reviews

2nd Floor beautiful 1 bedroom apartment.

This is a newly renovated second-floor apartment. There is washer dryer in the building. This apartment is set up for long-term stays. Please let us know if you have any questions about the property or about long-term stays. Caston Properties

Apr 28 – May 5

R1,237 ZAR per night