Vacation rentals in Coahoma County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Coahoma County

Guests agree: these stays are highly rated for location, cleanliness, and more.

%{current} / %{total}1 / 1
Guest favorite
A cozy corner seating area features a bright blue upholstered couch with decorative pillows. A low, circular wooden table is positioned centrally. A green door with a unique design adds character to the wall, while framed artwork and photographs adorn the surrounding space.
Apartment in Clarksdale
4.93 out of 5 average rating, 179 reviews

The Squeeze Box-"get your Blues on"

LOCATION-LOCATION-LOCATION The Squeeze Box is a spacious, airy 425 sq. ft. private vacation apartment, located in the heart of Historic Downtown Clarksdale, Mississippi. The newly constructed apartment is located on the ground floor of the former Clarksdale Telegraph Building (Circa 1897) @ the corner of Second & Delta in the Historic Blues District. Located across the street from the Hambone Art Gallery, and the “Rock & Blues Museum”, this is the best location in town. Gift shops around the corner. Restaurants including The Stone Pony, Yazoo Pass, Levon's Bar and Grill, and Grandma's House of Pancakes are literally all within 300 feet of our front door. CatHead Blues, Lambfish Gallery, and Hambone Gallery are all on our block. The Delta Blues Museum is a short walk, and Ground Zero Blues Club, New Roxy and Red’s Lounge are an easy 5-minute stroll. The Squeeze Box is the best location in Clarksdale for walkable access to restaurants, music venues, museums,bars, clubs,art galleries,shopping on Delta,convenience store,and the wine & spirits store. No need to drive once you check in.....park your car, and party to your heart's content. And The Squeeze Box is located on the ground floor, so there are no stairways to climb or drag your bags up. And we have a covered veranda out front with seating for six,so you can enjoy the fresh air, while enjoying a nice beverage. Although there is no smoking allowed in the apartment, the veranda is just outside your door. Available by the night,weekends, and weekly. Inquire about longer stays.

Guest favorite
The living room presents a comfortable seating arrangement with a beige sofa and green armchair, accompanied by wooden side tables. A faux fireplace is visible beneath a large TV mounted on the wall. Natural light filters through the partially covered window, enhancing the inviting space.
Home in Clarksdale
5 out of 5 average rating, 5 reviews

Casa D'Amore ! ! !

Our adorable house is your home away from home. We are less than 1/2 mile from downtown, where all the live blues are located. Our neighborhood is quiet. Everything you need is there. It is fully equipped for cooking, full size washer & dryer, Smart TVs, High-speed internet. Whether you are in town for a long weekend or for a longer stay, we are sure you will enjoy your stay. Clarksdale offers live blues every day of the week. There is no place like Clarksdale for authentic delta blues.

Guest favorite
A brick exterior home is set on a grassy lot, showcasing a wide driveway leading towards the entrance. Large windows allow natural light to illuminate the front rooms, while trees provide shade in the surrounding area.
Home in Tutwiler
5 out of 5 average rating, 5 reviews

Dollie’s Cove, A Veteran owned Hospitality Service

Relax with friends and family at this peaceful place to stay. 15 minutes from Clarksdale, MS. Open-concept living, dining room, kitchen. Four bedrooms with sitting chairs & luggage rack. Two bathrooms with towels, shampoo, conditioner, body wash, & hairdryer. Central Air & heat, Wi-Fi, Outside Cameras, Smart Lock, alarm, Refrigerator, Stove, Countertop Ice Maker, Waffle Maker, Rice Cooker, Toaster, Blender, Microwave, Flex Brew Trio Coffee Maker, washer (wifi compatible), dryer & television.

Guest favorite
The exterior of the home features a vibrant yellow front door, flanked by decorative plants. The brick facade and large windows provide a welcoming entrance. A well-maintained lawn surrounds the front, enhancing the inviting appearance of the property.
Home in Clarksdale
5 out of 5 average rating, 32 reviews

Delta Dream Retreat (Entire Home)

Relax with the whole family at this peaceful place to stay. we have put our heart and soul into renovating this entire home with all new appliances , bedding, furniture, mattresses, etc. It Is very modern and comfortable for families. It incl wi-fi, usb and multi movie channels every room, games, coffee, water, tea, and complimentary snacks. Only one camera[ring door bell] at the front door. Great neighbors and less than 2m from downtown Blues venues, Historical Crossroads, & eateries.

Superhost
A single-story home presents a classic brick façade with a prominent garage. The well-kept yard features neatly trimmed shrubs and lush greenery. The driveway leads to the garage, providing ample parking space. Large windows allow natural light to enter the living spaces.
Home in Clarksdale
4.72 out of 5 average rating, 170 reviews

Down Home Southern Charmer

This is the home that my sister and I grew up in with our parents and younger brother, who have passed on. We love our home, and are now opening it up to guests from anywhere in the world who want a comfortable place to stay while visiting the Mississippi Delta. Available to our guests are a centrally heated and cooled home with two bedrooms, a living/dining room, a family room with TV and Internet, two bathrooms, a kitchen, washer and dryer, and a garage. And, we just put in new floors!

Superhost
A cozy living area features two light-colored sofas opposite each other, adorned with decorative pillows. An intricate area rug covers the floor, complementing the rustic wooden walls and high ceiling. A room divider is positioned in the background, dividing the space from the bedroom. Natural light filters through the nearby windows.
Cottage in Clarksdale
4.91 out of 5 average rating, 318 reviews

Sunflower Cottage on the River

Only a mile from historic home of the blues, Clarksdale in a gated community. The cottage sits on the banks of the Sunflower River with beautiful views of rustic woods. Out your window you might see deer, fox & other wildlife. Take a walk along the riverbank. You’ll enjoy relaxing in the comfy beds, ,enjoy privacy, the piano , & closeness to all the blues music venues. It has two fire pits, an outside grill & full kitchen. Great for couples, adventurers, business travelers , musicians ,

Superhost
A charming blue cottage features a gabled roof and a white front door framed by two light fixtures. Two vintage chairs are positioned on the grassy area in front, surrounded by mature trees that provide some shade.
Cottage in Clarksdale
4.82 out of 5 average rating, 169 reviews

The Gallery at Chateau Debris

Welcome to The Gallery! This one-bedroom cottage sits behind the main house. It has recently been renovated, but is decorated with vintage furnishings for personality. The cottage is equipped with a full kitchen, bedroom, bathroom, washer and dryer, & Roku TV. Your stay will be unique, as the decor has been selected from my collector's lair, and the best part is - it's all for sale! The Gallery is a live-in collectibles showroom so, contrary to the saying - you CAN take it with you!

Guest favorite
A modern kitchen area features sleek black cabinetry and a wooden countertop with bar seating for three. Stainless steel appliances, including a refrigerator and microwave, are present, along with essential kitchen tools and a coffee maker conveniently arranged.
Loft in Clarksdale
4.85 out of 5 average rating, 13 reviews

Sunflower Loft A

Welcome to The Sunflower Lofts! These modern, fully furnished apartment-style accommodations are located in the heart of downtown Clarksdale. With a coffee shop just a few doors down and all the best restaurants & music venues within walking distance, you won't even need to get in the car until you leave! We accept long and short-term guests, so stay with us for one night or a few weeks! No pets. No smoking. Quiet hours begin at 10:00 pm. We do not accept local reservations.

Apartment in Clarksdale
4.67 out of 5 average rating, 3 reviews

Downtown Clarksdale Carriage House

Stay in the heart of downtown Clarksdale and enjoy all the charm, convenience, and music the Delta has to offer. This one-bedroom, one-bath apartment is the perfect home base for short or long term stays—modern, comfortable, and just steps from restaurants, shops, and world-famous blues venues. A highlight of this space is the private screened-in patio—your own quiet retreat where you can sip morning coffee, enjoy a book, or relax with a cocktail after exploring downtown.

Guest favorite
The brick exterior of Blues Hound Flat is characterized by large glass block windows and a centrally positioned red door. Horizontal blinds cover the windows, providing a sense of privacy while allowing light to filter through. A small air conditioning unit is visible above the door.
Loft in Clarksdale
4.93 out of 5 average rating, 441 reviews

Blues Hound Flat

Blues Hound Flat sits quietly across from the historic Greyhound bus station in the center of downtown Clarksdale. Step outside, and you're in the heart of the Delta Blues, surrounded by local eateries, shops, bars, and music venues! The air itself is heavy with the traditions of the Delta. This loft-style flat features all the basic amenities one could want and solitude when needed.

Guest favorite
The living area features exposed brick walls and large windows, providing natural light. A cozy couch is complemented by two side tables and lamps on either side. A decorative coffee table enhances the inviting atmosphere of the space.
Apartment in Clarksdale
4.9 out of 5 average rating, 30 reviews

High Cotton Condo Unit D

High Cotton Condo Unit D is centrally located in heart of downtown Clarksdale with 2 bedroom, 2 baths, and a foldout couch in the living room. This unit is updated and fresh with a large living room, a modern kitchen, and great retractable windows that look out onto Delta Avenue below! Condo D has all the modern luxuries you need to make your trip to Clarksdale complete!  

Guest favorite
A spacious living area features a comfortable seating arrangement with light grey sofas and a round ottoman. A wooden coffee table is centered, and warm lighting is provided by stylish floor lamps. Exposed brick walls add character, enhancing the modern rustic aesthetic.
Loft in Clarksdale
4.98 out of 5 average rating, 84 reviews

Delta Sunset Lofts - Historic 1910 Synagogue Apt B

Newly renovated one-bedroom loft style apartment in Clarksdale’s original 1910 Synagogue. Located within walking distance of the restaurants and clubs that make the Delta unique. With off street parking, a fully stocked kitchen, a washer and dryer, luxury linens, internet, and a unique style, 69 Delta is ideal for your weekend away or longer stay in Clarksdale.

Popular amenities for Coahoma County vacation rentals

Destinations to explore