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Guesthouse vacation rentals in Cameron County

Find and book unique guesthouse rentals on Airbnb

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Popular amenities for Cameron County guesthouse rentals

Family-friendly guest house rentals

Guest favorite
A view of a well-maintained property featuring lush greenery and flowering shrubs. The expansive lawn surrounds the home, while trees provide natural shade. The building's architecture is complemented by the surrounding flora, offering a tranquil setting within the landscape.
Guesthouse in San Benito
4.96 out of 5 average rating, 73 reviews

Magic Valley Outdoor Get-A-Way

JuanitaRating, 5 stars4 weeks ago
We enjoyed our stay. We were close to family members we were visiting. Also, we were close to South Padre and we would love to come back.
Guest favorite
A spacious room is furnished with two queen-size beds, each dressed in red floral bedding. Decorative panels adorn the walls, adding cultural detail. A nightstand with a lamp sits between the beds, and a cooling system is mounted above, ensuring comfort.
Guesthouse in Brownsville
4.79 out of 5 average rating, 163 reviews

EFICIENCY WITH 2 QUEEN AND KICHENET

DavidRating, 5 stars12 months ago
This is my second stay at Enrique's place. Absolutely enjoy staying there as it is located in a quiet and peaceful place. We enjoy having coffee in the balcony overseeing the beautiful resaca and all his beautiful plants. The beds are very comfortable and cozy. Has a nice kitchen and dining area. I highly recommend Enrique's place!!
Top guest favorite
The image shows a private outdoor area enclosed by greenery and a lattice fence. A small white chair is positioned on the patio, with foliage providing a natural backdrop. The cottage can be seen in the distance, surrounded by trees and shaded by plants.
Guesthouse in Harlingen
4.97 out of 5 average rating, 594 reviews

Private Cottage close to Airport

LorenaRating, 5 stars2 weeks ago
Very cozy and worth your stay!
A private covered patio is surrounded by lush greenery and tropical plants. A small table and two chairs are positioned under a wooden pergola, providing an inviting space for relaxation. The patio opens to the ground level entrance of the apartment.
Guesthouse in South Padre Island
4.8 out of 5 average rating, 132 reviews

Tropical Casita-Grounds w/Pool &Hot Tub

SherylRating, 5 stars4 months ago
Weather was not the best ie cold & rainy so spent more time in room. It was cozy and had what we needed to be comfortable . Kitchen was adequate . We travel with a small K Keurig pot and our own coffee so we had an easy am . So close to everything . The one nice day I was able to walk to the beach . All other restaurants were close and easy to get to. Bed was comfortable and really only comfy spot to watch to the rainy days . It’s basically a hotel room with nice patio area. Pool and hot tub are shared with others in the larger house area . We did not use either because of the weather. Meet other guests just once very nice . Dayna was helpful before and during our trip . Worked well for or first trip to SPI . Stayed 5 days looking for maybe 2 months next winter in a larger unit on the island

Guest house rentals with a washer and dryer

Guest favorite
A spacious pool area is surrounded by tropical landscaping, featuring a bright blue pool with a shallow entry and spa. Palm trees offer shade, while outdoor seating is arranged near a covered patio. A vibrant purple structure adds a pop of color to the scene.
Guesthouse in Port Isabel
4.95 out of 5 average rating, 20 reviews

Hacienda-style studio (Casa Luna)

JulianRating, 5 stars4 weeks ago
Great stay, very close to SPI and easy access to local restaurants. There is a park across the street which helped a lot with our dog walks in the mornings. Overall awesome place with a nice pool and very quiet. Will stay again in the future.
Superhost
A serene body of water reflects the colors of a sunset, with vibrant oranges and yellows blending softly into the sky. Silhouetted palm trees line the bank, creating a tranquil atmosphere. The gentle ripples of the water enhance the peaceful setting.
Private room in Rancho Viejo
5 out of 5 average rating, 20 reviews

BeautifulI Studio 4, Rancho Viejo Golf Resort

EzequielRating, 5 stars26 months ago
Good spot! recommend it
Guest favorite
Guesthouse in Los Fresnos
5 out of 5 average rating, 9 reviews

Bills Resaca Rental

NubiaRating, 5 stars5 months ago
This home was perfect for out needs. The view of the resaca is beautiful, and the remote location is nice for star gazing. The home was stocked with all the basic things we needed. Thank you for a lovely stay. We'd love to book again when we're in town.
Guest favorite
A vibrant pool area is framed by tall palm trees and lush landscaping. The clear water reflects the blue sky, while a partially shaded seating area is located under a trellis nearby. Steps lead into the pool, enhancing accessibility for relaxation.
Guesthouse in Port Isabel
4.92 out of 5 average rating, 26 reviews

Hacienda-style studio (La Casita)

VanessaRating, 5 stars1 week ago
Love everything about Martin & Isabel’s place! Very private, peaceful and comfortable! This is our 4th time staying , it is definitely our number one place in port Isabel!
A stacked washer and dryer unit is prominently positioned against a neutral wall. Below is a welcome mat with a bicycle design, enhancing the entryway's warmth. Gray tile flooring extends throughout the area, contributing to a clean and organized appearance.
Guesthouse in Brownsville
4.78 out of 5 average rating, 49 reviews

Centrally located guesthouse!

AlejandraRating, 5 stars5 months ago
Everything about the stay was great, highly recommended! We'll be back for sure 👌 Carlos always responded to our messages, everything was very good with the house, very clean and just as described in the listing!! Very good option to visit Brownsville and McAllen, very close to everything, very good location, very quiet and safe.
A dining area is set under a shaded umbrella, featuring a glass tabletop surrounded by four rattan chairs with leafy cushions. In the background, a private pool is visible alongside two loungers, offering a relaxing outdoor space.
Guesthouse in South Padre Island

House w/ Private Pool (Walking distance to beach)

Destinations to explore