
Vacation rentals in Williamston
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Top-rated vacation rentals in Williamston
Guests agree: these stays are highly rated for location, cleanliness, and more.

Luxury Retreat & Heated Pool Downtown Simpsonville
Luxury Pool House in the Heart of Simpsonville – Perfect for Gatherings! Designed for comfort, fun, and relaxation. 2 minutes from Downtown Simpsonville and 15 minutes from Downtown Greenville, this luxury retreat feels like a private resort with all the warmth of home. With nature views and countless amenities, you’ll have everything you need for an unforgettable stay. Up to 8 guests with 4 Spacious Beds and 2.5 Baths. Indoor & Outdoor Entertainment, Well-Equipped Kitchen, Cozy Living Room!
LocationFamilyIndoor spaces
4.93 out of 5 average rating, 111 reviews
Quaint farmhouse near Greenville and Clemson
This special property is near Greenville, Anderson, Clemson and more. Located just 3.6 miles from I-85 on Main Street West Pelzer, you can go any direction making this the perfect home base for exploring the Upstate. This 1917 home combines both charm and comfort, city and country. We strive to "think of everything" so your stay is fabulous. And you will love coming "home" after all your daily adventures! Now also available, The Canning House! See "other details" for more information!
FamilyValueAccuracy
5.0 out of 5 average rating, 93 reviews
Wildwood Farm Cottage
Welcome to Wildwoods Farmhouse, a thoughtfully designed modern farmhouse nestled on the grounds of Farm in the Wild Woods, a charming micro farm in Piedmont, SC. This is your chance to slow down, reconnect with nature, and experience the Upstate in a unique way. Spend your mornings sipping coffee on the back deck, stroll to the on-site farmstand for fresh seasonal produce, browse locally made goods, or pick up herbs and flowers from the nursery before heading out to explore Greenville.
LocationQuietNearby
5.0 out of 5 average rating, 3 reviews
Farmhouse • Greenville • Clemson •Lakes•Upstate SC
Discover the perfect blend of rustic charm and modern comfort in our 1920's fully renovated Villa Rosa farmhouse. Nestled in the countryside, this retreat offers an escape for families and friends while close to all. The whole family will have something to enjoy at this tranquil place. Enjoy a game night, sit by the fire pit, have a drink while rocking in the Adirondack chairs, or dive into a novel in the reading space. You'll enjoy the tranquility of nature in a comfortable setting.
LocationFamilyTV
4.98 out of 5 average rating, 56 reviews
Charming cottage on a Family Farm.
Your family will relish the convenience of this centrally located accommodation, along with spectacular views of farm animals. This charming 2-bedroom, 1-bathroom cottage is nestled on a quaint family farm, just a 5-minute drive from Interstate 85, exits 32 and 27. Conveniently positioned between Greenville and Anderson, it's also only a 20-minute drive to Clemson from the cottage. Moreover, the cottage features a fenced yard, and pets are welcome!
LocationFamilyAccuracy
4.96 out of 5 average rating, 156 reviews
Mr. Wilson’s Country Home
Quiet 3 ac country retreat perfect for Clemson & AU events, family time, foodie trip or a business stay. Quick access to I-85. Inside are 2 separate entertainment areas, large front porch, & screened porch in back. Take a peaceful walk on our road or enjoy the privacy and woods in back. The covered pavilion is the perfect place for a picnic or making memories around the fire pit. NO SMOKING, PETS or CHILDREN UNDER 3. Available for extended stay.
LocationFamilyCheckout
5.0 out of 5 average rating, 17 reviews
Guest Apartment @ Aletheia Farm
Nestled on 68 acres in the heart of Upstate South Carolina, we hope you find your time here as peaceful and relaxing as we do. We consider ourselves a small start-up family farm. On our property, you will find a working greenhouse with exterior raised beds, chickens housed in our chicken coop and honeybees in their hive. We love hospitality. We have welcomed friends to stay in our guest apartment and now desire to venture out and welcome others.
LocationFamilyIndoor spaces
4.98 out of 5 average rating, 47 reviews
Cabin with Saluda River access
Come and enjoy a beautiful stay just over the hill from the Saluda River. The cabin sits in the middle of 45 acres with 900 feet of river frontage. Less than thirty minutes from Greenville, Abbeville, Anderson, Laurens Greenwood and 15 minutes to Erskine College. If you are looking for a place to relax and enjoy a beautiful sunset, this is the place. The owners live on the property, so if anything is needed, we are just down the hill.
LocationValueAccess
5.0 out of 5 average rating, 24 reviews
Elegant 3BR Near Wed Venu | Grill+ Golf Next Door
Welcome to our spacious, family-friendly home in a beautiful neighborhood! Enjoy 3 bedrooms, including a master with a Temper-Pedic mattress. Modern amenities like FireTV, Italian coffee maker, and a fully equipped kitchen await. Work from our spacious office, relax on the tranquil patio, and stay connected with fast fiber optic internet. Perfect for families with cribs and high chairs available. Book now for comfort and convenience!
FamilyLocationHospitality
4.93 out of 5 average rating, 41 reviews
SC Farmstead Cottage w/ solitude & beautiful view!
Whether you are on vacation or a work-related trip, the SC Farmstead Cottage provides rest, comfort, and functionality so you can sip your coffee on the front porch at sunrise, or head out for the day to enjoy the many activities and sights across the Upstate. Come enjoy serenity, solitude & beautiful views! [Note: the total price displayed by AirBnB includes the AirBnB Fees, the $100 cleaning fee, & taxes.]
LocationFamilyComfort
5.0 out of 5 average rating, 42 reviews
Welcome to River House
Bring your fishing pole or kayak and enjoy this newly renovated cottage on a peaceful 3.5 acres nestled along the banks of the Saluda River. Centrally located 20 min from Greenville, 35 min from Clemson University and 25 min from Anderson, this beautifully appointed house has all the comforts of home. Enjoy your morning coffee on the large screened back porch while watching the abundant wildlife.
ValueLocationAccess
5.0 out of 5 average rating, 58 reviews
Cozy Pendleton Cottage ~ Minutes to Clemson
For your next getaway, escape to our Pendleton Cottage. Located just 9 miles from Clemson's Memorial Stadium and only 6 miles to Garrison Arena, you will find everything you need in our home away from home, including a full kitchen, a living room with a 65" TV, 3 bedrooms, each with its own 43" TV, 2 bathrooms, a huge fully fenced back yard, a full laundry room and so much more.
FamilyLocationCheck-in
5.0 out of 5 average rating, 206 reviewsPopular amenities for Williamston vacation rentals
Other great vacation rentals in Williamston

Riverfront A-frame cabin minutes from downtown
FamilyValueNearby
5.0 out of 5 average rating, 89 reviews
The Cozy Cabin at Mill Creek
LocationFamilyAccuracy
4.99 out of 5 average rating, 68 reviews
Luxury Country Chic
LocationFamilyComfort
5.0 out of 5 average rating, 27 reviews
Serenity On Broadway Lake
LocationValueView
4.97 out of 5 average rating, 36 reviews
North House - Charming home, walk to AU & AnMed
FamilyLocationQuiet
5.0 out of 5 average rating, 31 reviews
“What A View”- Lakefront on Broadway Lake
LocationFamilyOutdoor spaces
5.0 out of 5 average rating, 36 reviews
Lakefront 4BD Escape | Private Dock + Pet Friendly
HospitalityComfortIndoor spaces
5.0 out of 5 average rating, 3 reviews
Cozy home in the country
LocationValueHospitality
4.87 out of 5 average rating, 30 reviewsDestinations to explore
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