Vacation rentals in Williamston

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Top-rated vacation rentals in Williamston

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite

Cabin in Greenville

5.0 out of 5 average rating, 88 reviews

Riverfront A-frame cabin minutes from downtown

🌿 The Cabin at Fern Gully – Nestled on 36 acres of Camp Moondog's private wildlife sanctuary along the Saluda River. This 650 sq. ft. retreat offers two queen beds, a full bath, and modern comforts in a serene, natural setting just minutes from downtown Greenville, SC. 🌿Loft with Queen Bed 🌿Full Bath with Shower, Toilet, and Washer/Dryer combo 🌿Kitchen with Refrigerator, Sink, and Hot Plate 🌿Wrap around porch for beautiful Forest and River views 🌿Own private river spot with fire pit

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Guest favorite

The outdoor area showcases a tranquil pool surrounded by lush greenery, with comfortable lounge chairs positioned nearby. A pastel sunset provides a serene backdrop, while inflatable pool accessories add a playful touch to the inviting atmosphere.

Home in Simpsonville

4.93 out of 5 average rating, 110 reviews

Luxury Retreat & Heated Pool Downtown Simpsonville

Luxury Pool House in the Heart of Simpsonville – Perfect for Gatherings! Designed for comfort, fun, and relaxation. 2 minutes from Downtown Simpsonville and 15 minutes from Downtown Greenville, this luxury retreat feels like a private resort with all the warmth of home. With nature views and countless amenities, you’ll have everything you need for an unforgettable stay. Up to 8 guests with 4 Spacious Beds and 2.5 Baths. Indoor & Outdoor Entertainment, Well-Equipped Kitchen, Cozy Living Room!

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Guest favorite

The historic home is framed by large trees, showcasing a welcoming porch with a cozy seating area. The exterior features a flat metal roof and white walls, complemented by brick chimneys. A well-maintained lawn creates a serene setting among nature.

Home in Pelzer

5.0 out of 5 average rating, 93 reviews

Quaint farmhouse near Greenville and Clemson

This special property is near Greenville, Anderson, Clemson and more. Located just 3.6 miles from I-85 on Main Street West Pelzer, you can go any direction making this the perfect home base for exploring the Upstate. This 1917 home combines both charm and comfort, city and country. We strive to "think of everything" so your stay is fabulous. And you will love coming "home" after all your daily adventures! Now also available, The Canning House! See "other details" for more information!

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Top guest favorite

The front porch of the farmhouse features three rocking chairs positioned under a peaked roof. Potted flowers are placed at either end of the porch, complementing the welcoming entrance. A well-maintained pathway leads to the door, framed by landscaped greenery.

Home in Piedmont

4.98 out of 5 average rating, 54 reviews

Farmhouse • Greenville • Clemson •Lakes•Upstate SC

Discover the perfect blend of rustic charm and modern comfort in our 1920's fully renovated Villa Rosa farmhouse. Nestled in the countryside, this retreat offers an escape for families and friends while close to all. The whole family will have something to enjoy at this tranquil place. Enjoy a game night, sit by the fire pit, have a drink while rocking in the Adirondack chairs, or dive into a novel in the reading space. You'll enjoy the tranquility of nature in a comfortable setting.

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Top guest favorite

Home in Williamston

5.0 out of 5 average rating, 17 reviews

Mr. Wilson’s Country Home

Quiet 3 ac country retreat perfect for Clemson & AU events, family time, foodie trip or a business stay. Quick access to I-85. Inside are 2 separate entertainment areas, large front porch, & screened porch in back. Take a peaceful walk on our road to see the cows & babies- or enjoy the privacy and woods in back. The covered pavilion is the perfect place for a picnic or making memories around the fire pit. NO SMOKING, PETS or CHILDREN UNDER 3. Available for extended stay.

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Top guest favorite

The exterior of a cottage features a covered porch with two rocking chairs, surrounded by well-maintained landscaping. The building has a gray exterior, dark blue shutters, and a welcoming entrance, with trees providing a natural backdrop.

Cottage in Williamston

4.96 out of 5 average rating, 155 reviews

Charming cottage on a Family Farm.

Your family will relish the convenience of this centrally located accommodation, along with spectacular views of farm animals. This charming 2-bedroom, 1-bathroom cottage is nestled on a quaint family farm, just a 5-minute drive from Interstate 85, exits 32 and 27. Conveniently positioned between Greenville and Anderson, it's also only a 20-minute drive to Clemson from the cottage. Moreover, the cottage features a fenced yard, and pets are welcome!

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Top guest favorite

A spacious interior is revealed from an entryway, showcasing polished wood flooring and soft green walls. The open floor plan allows views of the kitchen and living area, where ample natural light enhances the inviting atmosphere. A staircase leads to an upper level in the background.

Loft in Piedmont

4.98 out of 5 average rating, 46 reviews

Guest Apartment @ Aletheia Farm

Nestled on 68 acres in the heart of Upstate South Carolina, we hope you find your time here as peaceful and relaxing as we do. We consider ourselves a small start-up family farm. On our property, you will find a working greenhouse with exterior raised beds, chickens housed in our chicken coop and honeybees in their hive. We love hospitality. We have welcomed friends to stay in our guest apartment and now desire to venture out and welcome others.

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Guest favorite

A charming brick house with a gabled roof is set on a spacious lot. A well-maintained lawn surrounds the home, while a paved driveway leads to a two-car garage. Large windows provide natural light, and a mailbox is positioned near the road.

Home in Anderson

4.93 out of 5 average rating, 41 reviews

Elegant 3BR Near Wed Venu | Grill+ Golf Next Door

Welcome to our spacious, family-friendly home in a beautiful neighborhood! Enjoy 3 bedrooms, including a master with a Temper-Pedic mattress. Modern amenities like FireTV, Italian coffee maker, and a fully equipped kitchen await. Work from our spacious office, relax on the tranquil patio, and stay connected with fast fiber optic internet. Perfect for families with cribs and high chairs available. Book now for comfort and convenience!

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Top guest favorite

A spacious grassy front yard is framed by several trees, providing shade and green foliage. The cottage, with its light-colored exterior, features a welcoming porch and adjacent covered area, visible through the lush lawn. A small structure is partially seen to the left.

Home in Belton

5.0 out of 5 average rating, 42 reviews

SC Farmstead Cottage w/ solitude & beautiful view!

Whether you are on vacation or a work-related trip, the SC Farmstead Cottage provides rest, comfort, and functionality so you can sip your coffee on the front porch at sunrise, or head out for the day to enjoy the many activities and sights across the Upstate. Come enjoy serenity, solitude & beautiful views! [Note: the total price displayed by AirBnB includes the AirBnB Fees, the $100 cleaning fee, & taxes.]

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Top guest favorite

A newly renovated cottage is set on a spacious lawn bordered by vibrant greenery. The exterior features a combination of light-colored brick and dark wooden accents. A welcoming path leads to the front entrance, framed by landscaped flowerbeds and trees that provide shade.

Home in Piedmont

5.0 out of 5 average rating, 57 reviews

Welcome to River House

Bring your fishing pole or kayak and enjoy this newly renovated cottage on a peaceful 3.5 acres nestled along the banks of the Saluda River. Centrally located 20 min from Greenville, 35 min from Clemson University and 25 min from Anderson, this beautifully appointed house has all the comforts of home. Enjoy your morning coffee on the large screened back porch while watching the abundant wildlife.

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Top guest favorite

A welcoming living room features a comfortable gray sofa and an armchair facing a wall-mounted TV. A round coffee table sits on a textured area rug. Natural light enters through the large front window, complementing the light wall color and wooden flooring.

Home in Pendleton

5.0 out of 5 average rating, 206 reviews

Cozy Pendleton Cottage ~ Minutes to Clemson

For your next getaway, escape to our Pendleton Cottage. Located just 9 miles from Clemson's Memorial Stadium and only 6 miles to Garrison Arena, you will find everything you need in our home away from home, including a full kitchen, a living room with a 65" TV, 3 bedrooms, each with its own 43" TV, 2 bathrooms, a huge fully fenced back yard, a full laundry room and so much more.

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Guest favorite

A spacious bed is centered against a light-colored wall, flanked by two bedside lamps. Decorative pillows in muted tones are arranged at the head of the bed, complemented by a soft, textured throw pillow. A piece of artwork hangs above the bed, adding a subtle visual interest.

Apartment in Williamston

4.94 out of 5 average rating, 53 reviews

Hope Ridge Hideaway

Take it easy at this cozy, tranquil country getaway with a farmette setting. We are located approximately 20 miles from Greenville, Clemson and Anderson with easy access to I85. This property sits on 16 wooded acres with walking trails to explore nature.. The apartment is situated in the back of the main house with its own private entrance.

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