
Vacation rentals in Santee River
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Top-rated vacation rentals in Santee River
Guests agree: these stays are highly rated for location, cleanliness, and more.
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Top guest favorite

Guesthouse in Summerville
5 out of 5 average rating, 39 reviews2 King beds 2 Bath*Gardens* Walkable Summerville
JohnRating, 5 stars2 weeks ago
Probably one of the nicest Air BnB’s we have ever stayed in! Beautifully decorated, comfy beds, spotless and large bathrooms. Thoughtful touches as well; coffee pods, snacks, and water were all provided. The grounds were beautifully landscaped as well with several outdoor sitting and relaxing areas. Our host lives on the grounds but did not intrude on our privacy in any way. We will definitely stay here again! I can’t recommend this property highly enough.

Home in Andrews
5 out of 5 average rating, 3 reviewsGraceful Comfort
JavantaeRating, 5 stars2 weeks ago
I Appreciated the welcoming stay while my family and I were in town for a funeral. Corey was understanding and respectful of the situation. Great host. 5 stars ⭐️⭐️⭐️⭐️⭐️
Guest favorite

Home in Moncks Corner
4.91 out of 5 average rating, 77 reviewsOur Home is Your Home!
AraRating, 5 stars2 weeks ago
The home was immaculate. We had everything we needed for a comfortable stay The beds were very comfortable. Kitchen had anything you needed to cook a meal. The neighborhood was quiet. Shelly answered any questions we had and quickly. She is by far one of the friendliest hostess, we have dealt with Our daughter and I are already talking about another trip there and will surely go to Shelly's.
Top guest favorite

Apartment in Summerville
4.98 out of 5 average rating, 45 reviewsThe Rustic Roost
BrittanyRating, 5 stars1 week ago
The Rustic Roost is very cute on the inside with beautiful green grass on the outside. The space had everything we needed to accommodate my family of four + our 12 year old pup. Great location for us as we were visiting for a busy graduation weekend. Owners let us know of an Adventure park nearby as well & our boys LOVED IT! Plenty of linens available for showering, blankets, & sheets if needed for the futon. We are already looking forward to our next adventure with TRR next year!🐓
Top guest favorite

Cottage in Hemingway
4.98 out of 5 average rating, 94 reviewsPeaceful cozy country cottage
MaryRating, 5 stars2 weeks ago
I absolutely loved Marie's place. I'm a city girl,the atmosphere of the country life is beautiful.Waking up to birds chirping and cows mooing was amazing. Everything was neat,clean, and peaceful. Ms. Marie was a great host and whenever I'm in town I wouldn't mind staying at her place.Thanks for everything Ms.Marie 😊

Cottage in Manning
4.74 out of 5 average rating, 141 reviewsA Great Lake house. Near Manning, SC and I-95.
KellyRating, 5 stars2 weeks ago
Ben was a super-responsive host. We had a great stay, and the cabin is peaceful. Perfect for a quiet restful vacation!
Top guest favorite

Farm stay in Georgetown
5 out of 5 average rating, 17 reviewsLo & Billy’s Place a historic 1940s Newlywed Cabin
MaryRating, 5 stars1 week ago
I loved it at Chris’s house! It was clean and well stocked with more items than I expected. It was so comfortable! The frig had milk, eggs, wine and even a pizza in the freezer. The chocolate chip cookies were a nice touch and they were delicious! They were very responsive and even alerted me to a storm that was brewing. The bed and bedding were comfortable. I loved the decorations! The cabin is about 5 miles from Georgetown. I was there to visit friends and family so the location was great for me. I look forward to staying there again.
Top guest favorite

Home in Cross
5 out of 5 average rating, 8 reviewsFish Haven
PatriciaRating, 5 stars1 week ago
This home was beautiful. Beds were very comfortable and my favorite was the bathtub!! Peaceful getaway and a sight to see with the lake right in the backyard!! My only issue was the lock pad but once we got inside it was amazing. We will definitely be back here again very soon!!!
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- Garden City Beach
- Sullivan's Island Beach
- Love's a Beach
- Huntington Beach State Park
- Middleton Place
- Hampton Park
- The Golf Club at Wescott Plantation
- James Island County Park
- Caledonia Golf & Fish Club
- Yeamans Hall Club
- Angel Oak Tree
- Shem Creek Park
- Broken Groin
- Waterfront Park
- Litchfield Beach and Golf Resort
- Morris Island Lighthouse
- White Point Garden
- The Charleston Museum
- Gibbes Museum of Art
- Isle of Palms Beach
- Shipyard Village Building A - Litchfield By The Sea
- Pawley's Island parking lot South
- Captain's Quarters Building C - Litchfield By The Sea
- Whirlin' Waters Adventure Waterpark