Vacation rentals in Sikeston

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Top-rated vacation rentals in Sikeston

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favorite

Apartment in Cape Girardeau

4.97 out of 5 average rating, 345 reviews

Beautiful Historic Boulevard District Apartment

This beautiful, private upstairs apartment is located on a favorite street in Cape Girardeau’s Historic Boulevard District. It is walking distance to SEMO University, Capaha Park, and the downtown riverfront. Recently remodeled for laundry, spacious rooms offer private bedroom spaces and a cozy den for watching movies or reading. The kitchen is fully equipped with amenities. This quiet neighborhood setting even has a front porch swing and sitting area where you can enjoy your morning coffee.

Jun 7 – 14

R1,851 ZAR per night
Guest favorite

Home in Jackson

4.92 out of 5 average rating, 263 reviews

The Rusty Owl-A Charming Victorian Dwelling

The Rusty Owl is a peaceful place with easy access to I-55. House has high speed (300 up and down) wifi. Jackson: Check out Flickerwood Arena, (9 minutes away... for ATV and barrel racing; horse shows and rodeos) Jackson History Center: Free. Open daily. Cape Girardeau: Live music and relaxation at The Library and 21 Taps. Hunter Valley Winery open weekends. 1 private lower level queen bedroom/ two private (1 queen, 1 twin) rooms and room with a antique full bed and a twin bed upstairs.

Nov 18 – 25

R2,005 ZAR per night
Guest favorite

Treehouse in Greenville

5.0 out of 5 average rating, 137 reviews

NEW treehouse B&B for 2 "The Roost” with hot tub

Cozy new 2022 custom built rustic but not primitive cabin 2 hours south of St Louis MO. Yes it has indoor plumbing and running water. Accommodates two adults only, has a fully equipped kitchen and breakfast items are provided for you to cook. Surrounded by thousands of acres of national forest. Observe wildlife sightings from the deck while soaking in the hot tub, sleep comfortably in a queen size pillowtop Serta bed on a Motion Air base, and relax as you enjoy the ambience of the fireplace.

Jan 10 – 17

R3,306 ZAR per night

Popular amenities for Sikeston vacation rentals

Other great vacation rentals in Sikeston

Guest favorite

Home in Dexter

4.88 out of 5 average rating, 65 reviews

Home Away from Home

Nov 3 – 10

R1,995 ZAR per night
Guest favorite

Home in Oran

4.88 out of 5 average rating, 49 reviews

The Blue Door

Sep 27 – Oct 4

R1,765 ZAR per night
Guest favorite

Treehouse in Cape Girardeau

4.98 out of 5 average rating, 53 reviews

Twisted Sassafras Treehouse

Mar 5 – 12

R5,153 ZAR per night
Guest favorite

Apartment in Dexter

5.0 out of 5 average rating, 40 reviews

Upstairs studio apartment

Dec 7 – 14

R1,521 ZAR per night
Guest favorite

Guesthouse in Dexter

5.0 out of 5 average rating, 35 reviews

The Cottage at Evergreen

Jun 13 – 20

R1,585 ZAR per night
Superhost

Home in Bloomfield

5.0 out of 5 average rating, 4 reviews

Ridge Road Cottage

Sep 13 – 20

R1,586 ZAR per night
Guest favorite

Cottage in Cape Girardeau

4.91 out of 5 average rating, 75 reviews

Country cottage with view of winding creek

Apr 26 – May 1

R2,758 ZAR per night
Guest favorite

Barn in Cape Girardeau

4.95 out of 5 average rating, 100 reviews

Under the Stars - Farmhouse

Nov 10 – 17

R4,077 ZAR per night
Guest favorite

Apartment in Cape Girardeau

4.97 out of 5 average rating, 59 reviews

Private Downtown Apartment

Oct 16 – 23

R2,377 ZAR per night
Guest favorite

Home in Campbell

5.0 out of 5 average rating, 43 reviews

Spacious, private, three bedroom country home.

Jan 3 – 10

R2,635 ZAR per night
Guest favorite

Cabin in Dexter

4.95 out of 5 average rating, 37 reviews

Cozy cabin on the hill!

Aug 14 – 21

R2,828 ZAR per night
Guest favorite

Guest suite in Cape Girardeau

5.0 out of 5 average rating, 92 reviews

Cape Comfy! Close to SEMO & Capaha! CLEAN! 5 Star!

Sep 4 – 11

R1,593 ZAR per night

Destinations to explore

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  2. United States
  3. Missouri
  4. Scott County
  5. Sikeston