Vacation rentals in De Soto

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in De Soto

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favorite

Tiny home in Viroqua

5.0 out of 5 average rating, 127 reviews

Little House on the Pretty! Tiny Home in Woods

Little House on the Pretty(LHP) is part of Sittin Pretty Farm. LHP is tucked into the woods giving a place to retreat and restore. The home is finely crafted embodying a simple elegance and character of the Driftless locale. Once inside, a sense of marvel and serenity are sure make heartfelt memories. We are six miles from Viroqua and nestled among Amish Paradise with several neighboring Amish farms. In season the Amish have roadside vegetable stands where you can purchase veggies and pie!

Jan 4 – 11

R1,992 ZAR per night
Guest favorite

Cabin in De Soto

5.0 out of 5 average rating, 23 reviews

Beautiful sunsets on the Great River

Experience the allure of the mighty Mississippii . This idyllic Driftless retreat offers everything you need for a tranquil getaway, complete with a spacious deck, a cozy fireplace, breathtaking riverboat views, and the majestic presence of eagles soaring overhead. Just 25 minutes to downtown La Crosse. Unwind and recharge as you step onto the expansive deck, where you'll be greeted by the soothing sounds of the flowing river. Breathe in the fresh air in the unparalleled beauty of nature.

Apr 7 – 12

R4,389 ZAR per night
Guest favorite

Cabin in Spring Grove

4.98 out of 5 average rating, 403 reviews

Modern Country Cabin

Clear your mind at this modern, fully furnished cabin in heart of the Driftless region of MN, WI, and IA. Built in 2016, this truly unique space has everything you need for a relaxing getaway. There is plenty of space inside the cabin. The cabin contains two private rooms, one with a king size bed and the other with a queen bed. In the summer months there is also opportunity to camp, with 4 acres of luscious green space + some woodlands! Indoor fireplace, outdoor fire pit, and Traeger grill!

Feb 12 – 19

R2,207 ZAR per night

Popular amenities for De Soto vacation rentals

Other great vacation rentals in De Soto

Guest favorite

Cabin in De Soto

4.95 out of 5 average rating, 63 reviews

RUSTIC RIDGE CHALET, hot tub, GRANDVIEW of RIVER!

Oct 13 – 20

R4,605 ZAR per night
Guest favorite

Cabin in De Soto

4.88 out of 5 average rating, 26 reviews

Paradise Point sleeps 4 Hot Tub

Nov 17 – 24

R6,405 ZAR per night
Guest favorite

Home in De Soto

5.0 out of 5 average rating, 25 reviews

Mississippi Escape

May 6 – 13

R3,519 ZAR per night
Guest favorite

Cabin in Eastman

4.88 out of 5 average rating, 17 reviews

The REAL ABNB

Sep 4 – 11

R2,350 ZAR per night
Superhost

Cabin in De Soto

4.9 out of 5 average rating, 21 reviews

Romance Valley Cabin on the River

Jul 24 – 31

R3,968 ZAR per night
Guest favorite

Cabin in De Soto

4.93 out of 5 average rating, 59 reviews

River View Lodge: Huge 3BR/3.5BA w/ stunning views

Sep 2 – 9

R9,719 ZAR per night
Guest favorite

Home in De Soto

5.0 out of 5 average rating, 47 reviews

Riverfront View

Dec 27 – Jan 3

R4,720 ZAR per night
Guest favorite

Tiny home in Lansing

4.88 out of 5 average rating, 43 reviews

Cheerful 1 bedroom cabin with lofted bedroom.

May 12 – 19

R1,705 ZAR per night
Guest favorite

Cabin in Genoa

4.99 out of 5 average rating, 75 reviews

Mee Mee's Cabin Retreat- River, nature, small town

Sep 11 – 18

R2,591 ZAR per night
Guest favorite

Cabin in Stoddard

4.92 out of 5 average rating, 39 reviews

Rustic River Cabin

Apr 19 – 26

R1,818 ZAR per night
Guest favorite

Tiny home in La Crosse

4.95 out of 5 average rating, 44 reviews

Come unwind with us at Kindred Tiny House.

Dec 8 – 15

R1,906 ZAR per night
Guest favorite

Cabin in Eastman

4.97 out of 5 average rating, 99 reviews

TranquiliTree Cabin- Secluded and Relaxing

Sep 25 – Oct 2

R2,932 ZAR per night

Quick stats about vacation rentals in De Soto

Total rentals

20 properties

Wifi availability

10 properties include access to wifi

Pet-friendly rentals

10 properties allow pets

Family-friendly rentals

10 properties are a good fit for families

Total number of reviews

340 reviews

Nightly prices starting at

R1,515 ZAR before taxes and fees

Frequently Asked Questions

  • Are there pet-friendly vacation rentals in De Soto?

    Four-legged friends are welcome in De Soto. Choose from more than 10 vacation rentals for guests traveling with pets.

  • Are there family-friendly vacation rentals in De Soto?

    De Soto has more than 10 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.

  • Do cabin rentals in De Soto have air conditioning?

    Absolutely! We offer over 10 cabin rentals with air conditioning in De Soto. Enjoy a tailored experience with all the comforts you desire.

  • Do cabin rentals in De Soto have free parking?

    Absolutely! We offer over 10 cabin rentals with free parking in De Soto. Enjoy a tailored experience with all the comforts you desire.

  • Do cabin rentals in De Soto have wifi?

    Absolutely! We offer over 10 cabin rentals with wifi in De Soto. Enjoy a tailored experience with all the comforts you desire.

  • Do cabin rentals in De Soto have a kitchen?

    Absolutely! We offer over 10 cabin rentals with a kitchen in De Soto. Enjoy a tailored experience with all the comforts you desire.

  • What are the most popular amenities for Cabin Rentals in De Soto?

    Enhance your stay in our Cabin Rentals with the most popular amenities: over 10 homes with air conditioning, over 10 homes with wifi, over 10 homes with a kitchen, over 10 homes with free parking, and more. Indulge in the ultimate retreat, tailored to your preferences.

  • How much does it cost to stay in cabin rentals in De Soto?

    Experience the best of De Soto with our cabin rentals, starting at about $110 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

Destinations to explore

  1. Airbnb
  2. United States
  3. Wisconsin
  4. Vernon County
  5. De Soto