Vacation rentals in Pike County

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Top-rated vacation rentals in Pike County

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A living area is presented with a floral-patterned couch and a light-colored coffee table, complemented by wooden flooring. An entertainment center holds a television and speakers, while a small chair and a decorative plant enhance the space. Natural light enters through multiple windows.

Apartment in Clarksville

4.83 out of 5 average rating, 12 reviews

Space, Light & Privacy..Serene

1400 sq ft fully furnished apartment with 2BR/2BA, full gourmet kitchen, situated in the historic downtown artisan district of Clarksville, MO. Gorgeous riverfront park view from living area with golf, kayaking, canoeing, bike trails, antiques, winery and fine dining in immediate proximity. Only an hour from St. Louis, your stay includes a $25.00 gift certificate in Bee Naturals, our bath and body shop, below. Second floor apartment with private rear entrance. DirectTV and WiFi are included and we're pet friendly, too. Off-street parking.

A modern farmhouse is presented in a spacious landscape, featuring a sleek metal exterior and a black roof. A covered porch extends along the front, providing a shaded area. Lush green grass surrounds the building, and a tree-lined backdrop adds natural depth to the setting.

Home in Eolia

New place to stay

DairyLand

Unplug and unwind in rustic luxury at this peaceful 2 bed, 1 bath farmhouse on 16+ acres in Eolia, MO. It's the perfect blend of simple living and pampered touches - where the stars shine bright and the cows say goodnight. What You'll Love: Farm-fresh eggs and raw milk from our happy herd, available daily Snuggle up to our sweet dairy cows and calves Indulge in handmade artisan soap for a spa-like soak Plenty of parking for trailers Easy day trips to Bowling Green, Wentzville, or St. Louis

Top guest favorite

A porch swing with a plush cushion and decorative pillows is suspended from the ceiling. A small side table holds a drink and a vase with a fresh flower. Lush greenery surrounds the area, offering a peaceful outdoor setting.

Home in Bowling Green

4.97 out of 5 average rating, 211 reviews

Peaceful Country Cottage

Traveling for work or pleasure? Enjoy a peaceful country view while relaxing on the front porch. This home sits on 14 acres, just off US Highway 61. Guests will see deer roaming in the yard early morning and at night. This rental accommodates families traveling with children or the couple seeking a quiet retreat. Stay here while you visit family and friends in the area. It is a short drive to Vandalia, Louisiana, Hannibal or Mark Twain Lake. (40 Min). About one hour from St. Louis.

Guest favorite

A log home nestled in a wooded area, featuring a distinct blue roof and multiple gabled sections. The surrounding trees show autumn foliage, and the home is set against a gentle slope of greenery. A covered porch extends across the front, inviting relaxation.

Cabin in Elsberry

5 out of 5 average rating, 29 reviews

Relaxing Log Home Getaway

This log home is approximately 3800 sq ft. 3 bedrooms, 4 full baths. All the amenities are there for your stay. Full kitchen, washer/dryer. 1 bedroom w/ Queen bed, 1 bedroom w/ Double bed & 3rd bedroom w/2 bunk beds, sleeps 4, & a pull out sofa couch in upstairs family room. Cozy up to the 20ft height fireplace/chimney or sit by fire outside. Plenty of room if you are planning a special trip with family or friends. Need some peace and quiet time. This is the place to relax/enjoy.

Guest favorite

An outdoor seating area is arranged around a circular fire pit, featuring several chairs positioned on a sandy surface. The lodge's exterior, with its metal siding and welcoming porch, is visible in the background, surrounded by lush green grass and hills in the distance.

Cabin in Nebo

5 out of 5 average rating, 35 reviews

Sweet Water Lodge

An exclusive lodge set in a private location, Sweet Water Lodge is the perfect place for you to get off the grid. With a state of the art kitchen, 5 bedrooms, and 3 bathrooms, it is great for big groups, families, or even a couple looking for a romantic getaway. Our lodge is surrounded by beautiful scenery, with a pond just steps out the front door. So whether you want to hike, float on the pond, or just relax on the front porch, Sweet Water Lodge is the perfect place to get away!

Top guest favorite

A dining area is furnished with a wooden table surrounded by black chairs, complemented by framed artwork on the wall. The kitchen can be seen in the background, featuring wooden cabinetry and stainless steel appliances, providing a modern touch to the space.

Condo in Bowling Green

5 out of 5 average rating, 28 reviews

Cozy Townhouse Retreat

Welcome to "Cozy Townhouse Retreat," a beautifully designed new construction offering three cozy bedrooms and 2.5 baths. This modern home features high-speed internet, a convenient washer and dryer, and a cozy fire pit for those chilly evenings. Outside, enjoy an outdoor gas grill and seating area, ideal for entertaining or relaxing. With a one-car garage and off-street parking, convenience is at your doorstep. Experience comfort, style, and modern amenities all in one place!

Top guest favorite

A single-story home with a welcoming covered porch is displayed. Greenery surrounds the house, and flower pots hang near the entrance. The porch features a pair of outdoor chairs, inviting relaxation. The light-colored exterior is complemented by a well-maintained lawn.

Home in Bowling Green

4.95 out of 5 average rating, 145 reviews

Home away from Home

A relaxing and inviting home away from home with everything that you need for your stay in Bowling Green. During your stay here you will enjoy the smart TV, free Wi-fi, and washer and dryer. A comfortable night’s sleep is a given with a brand new mattress on all three beds (queen bed and two twin beds). Located on the north side of town, you are less than 1 mile from Wood’s Smoked Meats and Bankhead’s Chocolates. This is an ideal base for your Pike County, MO visit.

Guest favorite

A river cabin sits elevated on stilts, surrounded by lush greenery, with a spacious deck offering views of the Mississippi River. A concrete patio leads to the water's edge, where a wooden dock allows for easy access. The peaceful setting is enhanced by mature trees in the background.

Treehouse in Annada

4.93 out of 5 average rating, 67 reviews

“Exclusive” River Cabin on Stilts (3 bedroom)

Your Perfect Riverfront Getaway Awaits! Nestled in a laid-back river cabin community, this charming cabin offers stunning views of the mighty Mississippi River. Whether you're into fishing or simply soaking up nature, the abundant wildlife and serene setting make it the ideal place to unwind. This cabin, elevated on stilts to protect from seasonal flooding, features three spacious bedrooms, one bath, and recent updates. Don’t miss out – book your escape today!

Guest favorite

The rustic cabin presents a welcoming facade with a blend of wood and stone finishes. A metal roof extends over the porch, offering protection from the elements. Surrounding the cabin, expansive grass lawns and mature trees contribute to the serene rural setting, under a clear blue sky.

Cabin in Middletown

5 out of 5 average rating, 17 reviews

Papa's Cabin - 40 acres & 5 acre lake!

Nestled in a rural country setting amidst Amish country, this spacious and rustic cabin sits on 40 acres, just 3.8 miles from the small town of Middletown, MO. Enjoy a lake for fishing, wide open fields, fire pit areas, and a BBQ space. Though this old cabin is far from fancy, it offers a clean, tidy, cozy and quiet atmosphere, even as we continue renovations and an ideal spot for your next staycation with ample room to explore the outdoors.

Guest favorite

A two-story yellow brick home is set against a bright blue sky. White trim outlines the windows and porch, while a manicured lawn and landscaping decorate the front. The structure features multiple windows, providing ample natural light.

Home in Louisiana

4.93 out of 5 average rating, 42 reviews

The Yellow Rose Historic Home

This cozy home is 8 blocks to the Mississippi. Beautiful overlooks, nice restaurants, historic homes. A short drive to Two Rivers Marina, the SLU Lay Center Sculpture Park, Hopewell Winery, Ted Shanks Conservation Area, Clarksville Apple Shed. 30 min. to Hannibal, MO - home of Mark Twain. 45 min. to Mark Twain Lake. 90 min. to St Louis. Plenty of sight-seeing, hunting, fishing, boating in the area. Fur babies are welcome.

Top guest favorite

A cozy living room is featured, showcasing a light-colored rug and a coffee table surrounded by comfortable seating. Large windows provide natural light and a view of the outdoors. A ceiling fan is positioned above, and soft curtains frame the windows.

Farm stay in New London

5 out of 5 average rating, 29 reviews

The Milkhouse

Get away from it all when you stay under the stars, commune with the cows and observe wildlife. See a working ranch and learn about farm life from us. Stay in a climate controlled modern farm house with lots of extras. Highway access and solid driveway to the farm house. Explore the hills, hollers and creeks. Close to Hannibal Mo and Mark Twain Lake among other local attractions.