Vacation rentals in Pike County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Pike County

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favorite

Place to stay in Hannibal

4.95 out of 5 average rating, 21 reviews

Ol’ Blue Gallery Guesthouse (studio loft)

It's rare to find a place that's both historic and one-of-a-kind. This cozy loft in the historic district sits above an art gallery about 3-4 blocks from the Mighty Mississippi & historic Main Street where you can walk to shops, restaurants and museums. It’s also walking distance to theaters, the farmers market and the stunning Sodalis Nature Preserve. The space is compact and the ceiling does slope down toward the T.V. & washer and dryer. Prefect for couples who spend their days exploring!

Apr 7 – 14

R1,501 ZAR per night
Guest favorite

Home in Pittsfield

4.83 out of 5 average rating, 201 reviews

Florence Guest House

This 1,200 sq. ft. PRIVATE BOOK is a 173 year old building that Abe Lincoln stayed in. Central A/C, Forced air heat, Two decks (one overlooking the Illinois River), burn pit, outside grill, fully equipped kitchen, screened in porch, ample parking, access to the Illinois River/ boat ramp near, tie up on Our Private Lots! NOTE: RECENTLY HAD Guests' wanting to "JUST GET AWAY" for A Time!!! WE'RE HERE, IF YOU NEED YOUR PRIVATE TIME ALONE, AS WELL!!! ***NEW KEURIG; BRING YOUR K-CUPS!!!***

Jun 19 – 26

R1,297 ZAR per night
Guest favorite

Home in Hannibal

5.0 out of 5 average rating, 27 reviews

Little House in the Hollow

Enjoy a private peaceful setting that is Conveniently located. Large fenced in yard for the kids and/or pets. Also has a 4 person hotub which is available year-round. The house is fully stocked for convenience. The house also has covered parking, outdoor fire pit, BBQ grill a play place for the kids and more. You will be within walking distance of 2 National Landmarks (Mark Twain Cave, Cameron Cave) as well as our Winery and Giftshop. Located just two miles from Hannibal's Historic District.

Jan 6 – 13

R3,500 ZAR per night

Popular amenities for Pike County vacation rentals

Other great vacation rentals in Pike County

Guest favorite

Home in Hannibal

4.96 out of 5 average rating, 55 reviews

Molly’s Riverview Retreat

Sep 7 – 14

R7,885 ZAR per night
Guest favorite

Home in Hannibal

5.0 out of 5 average rating, 12 reviews

The Widow Douglas-guest house

May 8 – 15

R5,348 ZAR per night
Guest favorite

Home in Hannibal

4.98 out of 5 average rating, 48 reviews

The Quarry House

Jan 2 – 9

R10,929 ZAR per night
Guest favorite

Home in Hannibal

4.88 out of 5 average rating, 17 reviews

The Indigo House

May 24 – 31

R5,421 ZAR per night
Superhost

Apartment in Hannibal

4.81 out of 5 average rating, 26 reviews

Huck Finn: Studio

Oct 9 – 16

R3,241 ZAR per night

Apartment in Hannibal

4.84 out of 5 average rating, 129 reviews

Farmhouse

Jun 21 – 28

R2,172 ZAR per night
Guest favorite

Loft in Pittsfield

4.82 out of 5 average rating, 22 reviews

Historic Loft on Adams

Jun 19 – 26

R1,162 ZAR per night
Guest favorite

Home in Pittsfield

5.0 out of 5 average rating, 8 reviews

Newly remodeled home

Jan 10 – 17

R2,807 ZAR per night
Guest favorite

Guesthouse in Pittsfield

4.87 out of 5 average rating, 15 reviews

Private Guesthouse Kitchen Washer Dryer Dishwasher

Mar 6 – 13

R1,638 ZAR per night
Guest favorite

Tiny home in Hannibal

5.0 out of 5 average rating, 6 reviews

The View on Reservoir

Aug 18 – 25

R3,691 ZAR per night
Guest favorite

Home in Hannibal

5.0 out of 5 average rating, 16 reviews

Historic Mansion-close to downtown-no cleaning fee

Aug 11 – 18

R14,072 ZAR per night

Home in Quincy

4.83 out of 5 average rating, 6 reviews

Cottage with Open Floor Plan

Feb 1 – 8

R2,930 ZAR per night

Destinations to explore

  1. Airbnb
  2. United States
  3. Illinois
  4. Pike County