Boutique hotel vacation rentals in Mississippi River

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Top-rated boutique hotel rentals in Mississippi River

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Top guest favorite

A spacious room features large windows overlooking Beaver Lake, allowing natural light to fill the space. A cozy sitting area includes a beige sofa and a rustic coffee table, while a queen pillow-top bed is positioned nearby. Accent walls of natural stone add texture to the room.

Hotel room in Eureka Springs

4.95 out of 5 average rating, 264 reviews

Romantic Lakeview Jacuzzi Suite

Jacuzzi Suites are the size of a hotel room with the privacy of a woodsy cabin. Our suites the perfect way to spend a romantic getaway. Each suite has a queen pillow-top bed, a sitting area, a Jacuzzi for two and a small deck with a stunning view of Beaver Lake. No kitchens; however, each one has a coffee bar w/ mini fridge, microwave and Keurig. Each suite has its own private boardwalk entrance to ensure privacy. We have 3 suites attached to the office building. No pets allowed in the suites.

Top guest favorite

The Grand Manor is showcased in an aerial view, framed by tall palm trees and a vibrant sunset sky. The elegant architecture features a three-story structure with a wrap-around porch, beautifully lit pathways, and lush greenery in the front yard.

Hotel room in Galveston

4.88 out of 5 average rating, 685 reviews

Tropicana Suite-Grand Manor Luxury Mansion Loft

The elegant Grand Manor (3.5 blks to cruise) Built 1905, a true southern tropical mansion. Luxury amenities seamlessly blended with Victorian grace (6 other rooms avail) Located in Galveston's East End Historic District , considered one of the top architectural structures on the Island Guest rooms are richly appointed, with king size beds. Private baths are soaker or claw-footed tubs. Best walking location to Island Funky bars & rooftop patios,harbor minutes to WORLD FAMOUS STRAND

Top guest favorite

The room features a queen size bed adorned with a decorative red and gold coverlet. Two windows are dressed with plush maroon curtains. A dresser with a mirror and a TV are positioned against one wall, while a faux fireplace adds warmth to the inviting space.

Hotel room in Osceola

4.93 out of 5 average rating, 108 reviews

Historic Commercial Hotel(1868),Sally Rand Suite

The Historic Commercial Hotel (Est.1868) on the Downtown square in beautiful Osceola,Missouri. Old world feel with modernized accommodations. The Historic Commercial Hotel has numerous themed rooms which are designed and named after past historical guests. This specific room is "The Sally Rand Suite". Named after past historical guest Sally Rand ( 1904 – 1979) who was an American burlesque dancer and Silver Screen star, most noted for her ostrich feather fan dance and balloon bubble dance.

Top guest favorite

A charming motor court unit is showcased, featuring rustic stone walls and vibrant green front doors. Two red chairs and a small table are positioned on the porch, complemented by a plant nearby. The structure is outlined against a clear sky.

Hotel room in Springfield

4.95 out of 5 average rating, 237 reviews

“Camp Rockwood”at Rockwood Motor Court on Route 66

Rockwood Motor Court, on historic Route 66, was built in 1929. Each room is themed and furnished to the era of Route 66. Camp Rockwood pays homage to the important history of motor courts along the road. It is decorated with historic photos of Rockwood and other courts and motels. Newly renovated in 2019, you’ll enjoy clean and comfortable room amenities while experiencing authentic motor court lodging. Need more space? We have larger rooms or can package multiple rooms for your group.

Guest favorite

The spacious studio features high ceilings and large industrial steel-frame windows, allowing natural light to fill the room. A modern sofa and armchairs are arranged around a wooden coffee table. A dining area with seating is visible, complementing the minimalist design.

Hotel room in St. Louis

4.91 out of 5 average rating, 134 reviews

Chic Ultramodern Studio Loft w/ Designer Features

The Nash Loft is a stunning minimalist studio with 12’ ceilings + bright 7’ industrial steel-frame windows, a spacious open layout, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, an Edison-illuminated community courtyard, and a fully-equipped kitchen with black stainless appliances and quartz countertops. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

Top guest favorite

The room features exposed brick walls and a wooden ceiling, enhancing the rustic charm. A spacious bed sits beside a cozy seating area with an orange armchair and a guitar. Natural light floods in through multiple large windows, with decorative elements like a cowhide rug and artwork adding character.

Hotel room in Hannibal

4.96 out of 5 average rating, 139 reviews

The Woodsman Suite

A third floor suite, facing the river with the train tracks only a couple blocks away. It took 2 months to do the ceiling. Carefully polished and placed the old lath in a specific design, the ceiling is a work of art. Eighty percent of the material used in this room is from re purposed lumber, either from this building or from a childhood barn built in the late 1800's. It will take you a while to notice every detail down to the toilet paper holder which is from an old barn post.

Guest favorite

A charming living area features a vibrant blue fireplace surrounded by decorative accents. A wooden coffee table rests on a cowhide rug, complemented by a brown leather couch. Colorful wall art and mirrors enhance the space, while a front door with stained glass adds character.

Hotel room in Eureka Springs

4.95 out of 5 average rating, 260 reviews

Clean, Eclectic, Private stay in Historic Loop

We offer a uniquely Eurekan experience on the upper loop of the Historic District. We are within walking distance to shopping, dining, and entertainment and right next to the trolly stop for those who prefer to ride! Enjoy two bath options with our oversized Jacuzzi tub or old-school claw-foot tub/shower! You will have a designated parking spot off the street and a private patio to people watch as you sip coffee, tea or a nightcap of your choice.

Top guest favorite

A well-lit room features a spacious bed topped with white bedding and pillows. A flat-screen TV is mounted on the wall opposite a large mirror, enhancing the sense of space. A sleek bathroom area is visible, showcasing modern fixtures and marble flooring.

Hotel room in Washington

4.95 out of 5 average rating, 101 reviews

River Sirens Hotel Junior Suite

11 Room Boutique Hotel in beautiful Downtown Washington. Each room has: Private Entrance Guest Access - Key Pad, Free Parking, King Size bed, TV, Wifi, Hair Dryer, Individual A/C & Heat. Guests can enjoy a shower room featuring a changing area with separate vanity and water closet spaces. Each room is also equipped with a full kitchen featuring large refrigerators with ice dispensers, induction stove top, microwave, toaster, and coffee station.

Guest favorite

A tranquil courtyard features a brick patio surrounding a small outdoor pool. Lush green plants and trees add natural beauty, while a stone archway leads to a secluded area. A round table with four metal chairs is positioned beside the pool.

Hotel room in New Orleans

4.96 out of 5 average rating, 150 reviews

Dauphine Street Balcony Suite + Courtyard Pool

Immerse yourself in the vibrant culture of New Orleans with a stay at this exquisite hotel suite, perfectly situated in the heart of the historic French Quarter. Just a stone's throw from the lively Bourbon Street, this accommodation offers unparalleled access to the city's renowned nightlife, eclectic shopping, and rich heritage. *Grenoble House is an all-adult boutique hotel *Grenoble House does not permit children under 13 years of age.

Top guest favorite

A spacious guest room is furnished with an antique queen bed and a vintage leather Chesterfield sofa. Natural light filters through the blackout shades, illuminating wooden flooring and a small dresser, while a large window offers a view. A decorative mirror is positioned beside the bed.

Hotel room in Galveston

5 out of 5 average rating, 131 reviews

#1 @ St. Helen's Hideaway + Cruise Port & Strand

Room #1 at Saint Helen's Hideaway -- This is the only downstairs guest room, no stairs to climb (except for the front porch stairs) and it's just steps from the kitchen, coffee bar, and back garden. It features an antique queen bed, blackout shades, a vintage leather Chesterfield sofa, and a flat-screen TV. There’s also an antique vanity and dresser, plus a private ensuite bathroom with classic black-and-white tile and a walk-in shower.

Top guest favorite

A spacious bedroom features a large wooden bed with decorative pillows and matching bedside tables. Soft lighting is provided by lamps on either side. Artwork with botanical themes adorns the wall above the bed, while a cozy chair adds an inviting touch to the warm-toned space.

Hotel room in Eureka Springs

5 out of 5 average rating, 174 reviews

STUNNING DOWNTOWN SUITE—private and convenient!

Welcome to Gorgeous! The Galloway Suite at Twilight Terrace offers the kind of comfortable elegance that will make you sigh when you enter. Beautiful and spacious, it has everything. Full kitchen, Wifi, flat screen TV, jet tub for 2—and an enormous shower with dual heads and misters. Throw in OFF-STREET PARKING and you’re home! Please be aware there is a staircase to get to the suite. It is well lit and has sturdy handrails!

Top guest favorite

A spacious bedroom features exposed brick walls and wooden beams, creating a rustic atmosphere. A grand wooden bed is complemented by two bedside lamps. A seating bench is positioned at the foot of the bed. Natural light enters through a large window, enhancing the room's open feel.

Hotel room in Natchez

4.94 out of 5 average rating, 250 reviews

The River Walk Inn - Room 801

Spacious upstairs room in a charming 1840's building located on top of the bluff with exquisite views of the MS river. This room has beautiful period furniture, a Keurig, mini fridge, access to a shared balcony, ice machine, washer/dryer, and is within walking distance to all events downtown. Please note that the rooms are above a popular restaurant/bar that frequently offers live entertainment on the weekends.