Vacation rentals in Mesa, Phoenix

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Top-rated vacation rentals in Mesa, Phoenix

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A spacious driveway is shown, featuring a parked car on the left and a paved path leading toward a white guest house. Lush greenery is visible with several trees and shrubs, creating a peaceful outdoor setting.
Guesthouse in Paradise Valley Village
4.96 out of 5 average rating, 215 reviews

Clean and Cozy Guest Home

MESSAGE US IF YOU ARE LOOKING FOR A 3+DAY STAY IF DAYS APPEAR UNAVAILABLE! We are located in Northeast Phoenix in a safe quiet family neighborhood. We are 1/2 mile from the 51 and 101, less than 10 min from PV restaurants, & 20 min away from Sky Harbor Airport. Private guest house can accommodate 6 guests with 2 bedrooms with 1 Queen bed each, 1 Queen sleeper sofa in living room, 1 bathroom, and full kitchen. There are TVs in the common area as well as one bedroom. NO PETS,NO PARTIES,NO SMOKING

Top guest favorite
A well-lit bedroom features a spacious bed with crisp white linens and decorative pillows. A large mirror reflects the natural light, while a potted plant adds a touch of greenery. Soft textures are present with a woven rug beneath the bed and bedside tables on either side.
Home in Paradise Valley Village
4.97 out of 5 average rating, 137 reviews

Spacious Backyard & Office Near Mayo Clinic

Near Mayo Clinic Hospital, located in a quiet neighborhood in Paradise Valley Village, our fully remodeled home, offers the perfect stay for couples, families, or business guests. Enjoy fast Wi‑Fi, a dedicated work room, washer/dryer, FREE parking with RV gate, and a gourmet kitchen. Relax after adventure in the expansive backyard with cornhole games, or binge shows on the 75″ TV. Minutes from hiking, golf, dining, and Phoenix attractions. 15 min/11 miles to Airport —your desert getaway awaits!

Guest favorite
The open-concept living area features a light-colored sectional sofa paired with a wooden coffee table displaying decorative items. A dining area with a round table is visible, alongside a modern kitchen equipped with sleek cabinetry and bar stools. Natural light fills the space through multiple windows.
Home in Paradise Valley Village
4.98 out of 5 average rating, 183 reviews

Renovated Modern Boho | Pool/Hot Tub | PHX Vibes

Welcome to The Agave Abode by Desert Living Collective! This modern boho inspired 3BR/2B home will immerse you in what desert living is all about. Take a dip in the pool or relax in the hot tub and enjoy your private outdoor retreat with mountain views. Walking distance to Shadow Mountain and close to ample dining, shopping & activity options - you cannot beat this location! Lounge in the sun and catch some vibes with this beautiful home in the heart of Phoenix just 20 minutes from PHX airport.

Top guest favorite
Guesthouse in Paradise Valley Village
4.99 out of 5 average rating, 147 reviews

Urban Cabin - A unique Retreat

Escape to this one-of-a-kind cedar cabin, offering a private sanctuary in the heart of the city. Thoughtfully designed w/a modern edge, it features expansive windows flooding interior w/natural light yet maintaining a cozy, secluded feel. Outside, a private yard, where you'll find an antique clawfoot tub/shower, perfect for unwinding under the open sky. Inside, industrial elements blend seamlessly w/warm cedar tones, creating an inviting atmosphere ideal for both relaxation & inspiration.

Top guest favorite
A serene outdoor area features a private swimming pool reflecting palm trees and a clear blue sky. Comfortable lounge chairs surround the pool, alongside a shaded seating area under an umbrella, offering a perfect space for relaxation.
Villa in Paradise Valley Village
4.97 out of 5 average rating, 248 reviews

Villa de Paz

Looking for a sanctuary, a romantic getaway, a hiking haven? Come to Villa de Paz, a fully furnished, one bedroom casita, located on 2+ acres in the heart of Central Phoenix. Villa de Paz is located within walking distance of the Phoenix Mountain Preserve, known for its phenomenal hiking trails. Or, you can lay at the pool during the day and sit around the fire pit in the evening. Many restaurants are nearby or within minutes, you can drive to Scottsdale for shopping and entertainment.

Guest favorite
A spacious living area features a comfortable seating arrangement with a view of the outdoors. A dining table is positioned near large windows, allowing natural light to fill the room. The kitchen is equipped with modern appliances and ample counter space for meal preparation.
Home in Paradise Valley Village
4.84 out of 5 average rating, 220 reviews

The Cove at Scottsdale: Spacious 4BR + Heated Pool

Escape to this spacious Phoenix home right near the Scottsdale border, offering a great central location and plenty of room for your group to unwind. Enjoy the warm Arizona weather in your private backyard featuring a heated pool, BBQ, and a covered patio for relaxed outdoor living. Ideal for casual family trips or friend groups looking for a comfortable, laid-back home base, this desert retreat provides the space and convenience you need just minutes from top local attractions.

Guest favorite
The backyard features a heated pool surrounded by sun loungers and vibrant landscaping. A hot tub can be seen beside the pool, while a shaded outdoor seating area and BBQ grill are available under the covered patio. Lush palm trees provide a tropical feel.
Home in Paradise Valley Village
4.92 out of 5 average rating, 132 reviews

Serene Home, Heated Pool & Games

This serene home can fit up to 22 guests with its 7 bedrooms and 4 bathrooms. With lots of upscale amenities and a stunning heated pool and spa in the backyard, this home is your ultimate travel destination. Filled with sunlight and professionally selected décor, this airy and classy home is custom-designed for large groups to experience extravagant living. The professionally designed spaces offer open-concept layouts and kitchen & dining spaces perfect for entertaining.

Top guest favorite
The hillside home is framed by lush landscaping, featuring various desert plants including tall cacti and palm trees. A manicured lawn leads up to the house, which showcases large windows that reflect the surrounding beauty.
Home in Camelback East
4.99 out of 5 average rating, 135 reviews

The ViewPointe! Mountain & Cityscape

Stay here and immerse yourself in the natural romantic beauty of Arizona. Enjoy not only stunning mountain views but also the cityscape of downtown Phoenix. With walls of windows bringing the outside in, a spacious living area, king beds, and idyllic private patios, let the beauty of nature be the backdrop for sweet memories in our hillside mid century view home. Only 15 minutes from the airport, our guests love the convenient central city location.

Top guest favorite
A bright living area features a grey sofa adorned with vibrant pillows, complemented by a patterned chair. A wooden coffee table sits on a textured rug. Natural light streams through large windows, illuminating a dining table set for four against a backdrop of white walls.
Guesthouse in Paradise Valley Village
5.0 out of 5 average rating, 117 reviews

Private, Spacious, Desert View on 1.5 acres!

Light, bright, airy, private, and recently renovated 1100 sq ft. unit. Great for people who love both an urban and nature experience. Perfectly situated next to the Phoenix Mountain Preserve, which has some of the best hiking and mountain biking in the city just minutes from your doorstep. Despite having a quiet country feel, we're close to restaurants, coffee shops, grocery stores in Scottsdale, Paradise Valley, and downtown Phoenix.

Top guest favorite
A serene outdoor space features a tranquil swimming pool, bordered by sleek tile and lush landscaping. Comfortable lounge chairs are positioned by the pool, reflecting a leisurely atmosphere. Expansive glass doors provide a view of the connected casita units beyond, enhancing the indoor-outdoor experience.
Guesthouse in Paradise Valley Village
5.0 out of 5 average rating, 73 reviews

Modern Casita Nestled in Tranquil Sonoran Desert

An architectural delight - designed and remodeled by nationally re-known Construction Zone, Ltd. - this casita is perfectly located in a north central Phoenix neighborhood. Amazing access to Phoenix Mountain Preserve, dining, nightlife, cultural events and more. The casita has a private entrance with access to shared courtyard, pickleball court and swimming pool. The architecture, construction and decor is impeccable. Come enjoy!

Guest favorite
A resort-style heated pool is featured, surrounded by palm trees and lounge chairs. A covered patio area with seating is visible, and a gentle waterfall effect adds a soothing touch. The sky transitions from orange to purple at sunset, enhancing the tranquil setting.
Home in Paradise Valley Village
5.0 out of 5 average rating, 24 reviews

HÓZHÓ | Golf-Themed Home: Putting Green & Hot Tub

This 5-bedroom Scottsdale home features a private putting green, arcade games, heated pool, hot tub, and fire pit in a fully fenced backyard. Inside, a pool table and dedicated workspace complement the gourmet kitchen. Close to championship golf courses, Old Town, and Spring Training venues. Built for multi-generational families and golf groups seeking entertainment on-site and quick access to Scottsdale's top attractions.

Top guest favorite
An open living area features large windows offering panoramic views of the surrounding landscape. A spacious sectional sofa sits in the foreground, accompanied by a hanging chair. A dining area with a modern table and chairs is visible, enhancing the inviting space for relaxation and dining.
Home in North Mountain
4.99 out of 5 average rating, 551 reviews

*360degree views of Phx/for couples/Decks/Hot Tub

The “Nest” sits proudly atop a mountain, offering stunning 360° views of Phoenix. Every window frames mesmerizing panoramas, making your stay truly immersive. The property is thoughtfully equipped with all the amenities you need for ultimate relaxation.

Popular amenities for Mesa, Phoenix vacation rentals