Vacation rentals in Mesa, Phoenix

A spacious driveway is shown, featuring a parked car on the left and a paved path leading toward a white guest house. Lush greenery is visible with several trees and shrubs, creating a peaceful outdoor setting.

4.96 out of 5 average rating, 215 reviews

Clean and Cozy Guest Home

MESSAGE US IF YOU ARE LOOKING FOR A 3+DAY STAY IF DAYS APPEAR UNAVAILABLE! We are located in Northeast Phoenix in a safe quiet family neighborhood. We are 1/2 mile from the 51 and 101, less than 10 min from PV restaurants, & 20 min away from Sky Harbor Airport. Private guest house can accommodate 6 guests with 2 bedrooms with 1 Queen bed each, 1 Queen sleeper sofa in living room, 1 bathroom, and full kitchen. There are TVs in the common area as well as one bedroom. NO PETS,NO PARTIES,NO SMOKING

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4.98 out of 5 average rating, 43 reviews

5 BR / Heated Pool / Fire Pit / BIG Backyard in PV

Step inside to a vibrant North Phoenix retreat where every corner feels brand new. Enjoy 5 stylish bedrooms with LED Smart TVs in every room, sleek white-oak modern cabinetry, quartz counters with island waterfall, and spacious double living rooms. Out back, stretch out and enjoy the massive 1/3-acre oasis with a heated pool, 10 luxe pool loungers, pergola dining, Adirondack seating and fire pit for six, a fun 3-hole putting green, and warm bistro lights that brings the entire backyard together.

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A well-lit bedroom features a spacious bed with crisp white linens and decorative pillows. A large mirror reflects the natural light, while a potted plant adds a touch of greenery. Soft textures are present with a woven rug beneath the bed and bedside tables on either side.

4.97 out of 5 average rating, 138 reviews

Spacious Backyard & Office Near Mayo Clinic

Near Mayo Clinic Hospital, located in a quiet neighborhood in Paradise Valley Village, our fully remodeled home, offers the perfect stay for couples, families, or business guests. Enjoy fast Wi‑Fi, a dedicated work room, washer/dryer, FREE parking with RV gate, and a gourmet kitchen. Relax after adventure in the expansive backyard with cornhole games, or binge shows on the 75″ TV. Minutes from hiking, golf, dining, and Phoenix attractions. 15 min/11 miles to Airport —your desert getaway awaits!

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The entrance features a pair of double doors adorned in a vibrant purple hue, framed by large windows on either side. Potted plants are positioned at the base of each window, enhancing the welcoming feel. A covered walkway provides shelter from the elements.

4.98 out of 5 average rating, 56 reviews

The Bunkhouse

A hidden gem. Unwind and relax from work or play at this cozy stand alone bunkhouse just 15 minutes from Sky Harbor Airport in the middle of Phoenix. Located close to cycling, hiking and horse trails at the Phoenix Preserve this get away allows a quiet retreat location with shopping and restaurants nearby. A separate entrance and covered parking provides privacy. Excellent internet connection allows access to streaming services. Enjoy all Phoenix has to offer from this sweet, restful spot.

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4.98 out of 5 average rating, 126 reviews

An aerial view showcases the home nestled within a canyon, surrounded by palm trees and mountain peaks. The inviting pool features lounge chairs arranged around its edges, providing a serene outdoor space. A lush green lawn complements the pool area, creating an ideal relaxation spot.

Villa in Paradise Valley

Private Canyon Retreat: Pool, Gym + Mountain Views

Nestled in a 1.5 acre canyon surrounded by soaring peaks and majestic Saguaro cacti, this newly renovated "Japandi-inspired," architectural home embraces the natural warmth of Japanese and Scandinavian design. Designed for an ultimate restorative desert escape, the home offers a range of relaxation and activity. Whether your idea of restoration is sipping wine by the brand-new sun-drenched pool, hiking, vinyassa on the lawn, or catching a class on the brand-new Peloton, this home has it all.

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4.99 out of 5 average rating, 149 reviews

Urban Cabin - A unique Retreat

Escape to this one-of-a-kind cedar cabin, offering a private sanctuary in the heart of the city. Thoughtfully designed w/a modern edge, it features expansive windows flooding interior w/natural light yet maintaining a cozy, secluded feel. Outside, a private yard, where you'll find an antique clawfoot tub/shower, perfect for unwinding under the open sky. Inside, industrial elements blend seamlessly w/warm cedar tones, creating an inviting atmosphere ideal for both relaxation & inspiration.

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Villa in Paradise Valley Village

A serene outdoor area features a private swimming pool reflecting palm trees and a clear blue sky. Comfortable lounge chairs surround the pool, alongside a shaded seating area under an umbrella, offering a perfect space for relaxation.

Villa de Paz

Looking for a sanctuary, a romantic getaway, a hiking haven? Come to Villa de Paz, a fully furnished, one bedroom casita, located on 2+ acres in the heart of Central Phoenix. Villa de Paz is located within walking distance of the Phoenix Mountain Preserve, known for its phenomenal hiking trails. Or, you can lay at the pool during the day and sit around the fire pit in the evening. Many restaurants are nearby or within minutes, you can drive to Scottsdale for shopping and entertainment.

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4.97 out of 5 average rating, 249 reviews

Guest favorite

A spacious living area features a comfortable seating arrangement with a view of the outdoors. A dining table is positioned near large windows, allowing natural light to fill the room. The kitchen is equipped with modern appliances and ample counter space for meal preparation.

4.84 out of 5 average rating, 221 reviews

The Cove at Scottsdale: Spacious 4BR + Heated Pool

Escape to this spacious Phoenix home right near the Scottsdale border, offering a great central location and plenty of room for your group to unwind. Enjoy the warm Arizona weather in your private backyard featuring a heated pool, BBQ, and a covered patio for relaxed outdoor living. Ideal for casual family trips or friend groups looking for a comfortable, laid-back home base, this desert retreat provides the space and convenience you need just minutes from top local attractions.

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Guest favorite

The backyard features a heated pool surrounded by sun loungers and vibrant landscaping. A hot tub can be seen beside the pool, while a shaded outdoor seating area and BBQ grill are available under the covered patio. Lush palm trees provide a tropical feel.

4.91 out of 5 average rating, 133 reviews

Serene Home, Heated Pool & Games

This serene home can fit up to 22 guests with its 7 bedrooms and 4 bathrooms. With lots of upscale amenities and a stunning heated pool and spa in the backyard, this home is your ultimate travel destination. Filled with sunlight and professionally selected décor, this airy and classy home is custom-designed for large groups to experience extravagant living. The professionally designed spaces offer open-concept layouts and kitchen & dining spaces perfect for entertaining.

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4.99 out of 5 average rating, 135 reviews

The hillside home is framed by lush landscaping, featuring various desert plants including tall cacti and palm trees. A manicured lawn leads up to the house, which showcases large windows that reflect the surrounding beauty.

Home in Camelback East

The ViewPointe! Mountain & Cityscape

Stay here and immerse yourself in the natural romantic beauty of Arizona. Enjoy not only stunning mountain views but also the cityscape of downtown Phoenix. With walls of windows bringing the outside in, a spacious living area, king beds, and idyllic private patios, let the beauty of nature be the backdrop for sweet memories in our hillside mid century view home. Only 15 minutes from the airport, our guests love the convenient central city location.

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A bright living area features a grey sofa adorned with vibrant pillows, complemented by a patterned chair. A wooden coffee table sits on a textured rug. Natural light streams through large windows, illuminating a dining table set for four against a backdrop of white walls.

5.0 out of 5 average rating, 117 reviews

Private, Spacious, Desert View on 1.5 acres!

Light, bright, airy, private, and recently renovated 1100 sq ft. unit. Great for people who love both an urban and nature experience. Perfectly situated next to the Phoenix Mountain Preserve, which has some of the best hiking and mountain biking in the city just minutes from your doorstep. Despite having a quiet country feel, we're close to restaurants, coffee shops, grocery stores in Scottsdale, Paradise Valley, and downtown Phoenix.

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A serene outdoor space features a tranquil swimming pool, bordered by sleek tile and lush landscaping. Comfortable lounge chairs are positioned by the pool, reflecting a leisurely atmosphere. Expansive glass doors provide a view of the connected casita units beyond, enhancing the indoor-outdoor experience.