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Vacation rentals in Hampton County

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Top-rated vacation rentals in Hampton County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Home in Varnville
New place to stay

Hank and Margie's Place

“Peaceful!! Nestled in the Lowcountry, a cozy look and Big City Feel” – “Hank and Margie’s Place” This home is in a charming quiet neighborhood off Hwy 63/ 64, at the end of a cul-de-sac. "Perfect" for traveling construction/maintenance crews, health care professionals. Less than 1 mile to 1 local hospital, 10 Miles from Allendale County, 24 Miles from Colleton Regional, 44 Miles from Beaufort Memorial. Accommodates comfortably 4 Guests - 4 BR, 2.5 BA, full home generator & Very Clean. The space This house is perfect for a "staycation". It is work friendly (desk, Wi-Fi and printer) and its family/children friendly. The inside has a beautiful open concept from living room, dining room and kitchen, plenty of space for a family of four. For the chefs, the kitchen is fully stocked with just about anything you could think of or need. We offer breakfast sandwiches, eggs. fruit cups. yogurt, sliced cheese, frozen waffles, in as tant grits/oatmeal, cereal, fresh bananas, and of course: Orange Juice Cranberry Juice, Tea, Coffee, AND Hot Chocolate. For the cereal lover, because of the different Milk products...., this is not provided. Amenities: Welcome Packet to include important Local Town Information of Upcoming Calendar of Events, Public Safety, Fire Department, Popular Restaurants) Home Fully Furnished - All you need to bring is your suitcase, groceries/snacks, and your favorite pillow!! Outside Patio with a Gas Grill. Full In-House Generator is a great benefit that comes equipped within the residence for any Electrical outages. Key Less Entry Doors. For Prior to Check-in Time, you will be provided the Security Code. Fenced in Doggie Yard for 1 Outdoor Large Dog Dog Friendly: Small Pets inside allowed (maximum 15 pounds) High Speed WiFi, Streaming and Internet. Quality Bedding Spacious Parking for up to 5 cars Open Concept with Full Kitchen; Gas Stove Microwave Kitchen Essentials - Dishes/Utensils/Glasses/Pots and Pans Dishwasher HVAC Full Size Upright Refrigerator Tabletop Ice Maker Machine Side By Side Washer/Dryer - In Unit Laundry Wall Mounted TV in Common Area TV in each Bedroom-Will need to bring your Firestick/XUMO/or ROKU and Remote to operate. Coffee Keurig Station Tea/Hot Chocolate Station Access entire house and yard Swing Set to enjoy the evening breeze. Other things to note Great for remote work Midterm Rentals - 2 Week, 3 Week, 1 Month, 3-6 months, and/or 6-12 months also available at a negotiable rate to any Construction Crews or Traveling Business Professionals. Close proximity to areas hospitals, schools, and businesses. If this is a connection you'd want to inquire about, reach out directly to the host for further details.

Top guest favorite
Home in Varnville
5 out of 5 average rating, 19 reviews

Hank and Margie's Place

“PEACEFUL!! Nestled in the Lowcountry, a COZY LOOK AND Big City FEEL” – “Hank and Margie’s Place” This home is in a charming quiet neighborhood off Hwy 63/ 64, at the end of a cul-de-sac. "Perfect" for traveling construction/maintenance crews, health care professionals. Less than 1 mile to 1 local hospital, 10 Miles from Allendale County, 24 Miles from Colleton Regional, 44 Miles from Beaufort Memorial. Accommodates comfortably 4 Guests - 4 BR, 2.5 BA, FULL HOUSE GENERATOR & Very CLEAN.

Home in Yemassee
5 out of 5 average rating, 5 reviews

Private Historic Home in Downtown Yemassee

Historic bungalow located just minutes from I-95 and a short drive to Beaufort. This cozy house is perfect for weary travelers or weekend getaways. Enjoy inviting living spaces, a fully equipped kitchen, and a large private backyard. Sit on the front porch under the grand live oaks or gather around the fire pit for a relaxing evening. Whether you are attending a wedding, graduating a Marine, antiquing, or hunting/fishing nearby, this is the place for you. Extended stays are welcome as well.

Top guest favorite
Home in Estill
4.98 out of 5 average rating, 63 reviews

The Cottage

Reconnect with loved ones in this family-friendly place-- a peaceful setting in the South Carolina Low Country. We are centrally located in Estill, SC off of hwy 321. Our home is ideal for visiting hunters 🦌 (some of the best hunting in the state), tourist 📸, golfers⛳, or anyone desiring a peaceful escape🧘🏾‍♀️. Our home is clean, newly renovated, cozy, and fully electric. Explore nearby Lake Warren State Park, Beaufort, Hilton Head Island, and Savannah. Our home is ready for you!

Top guest favorite
Home in Furman
5 out of 5 average rating, 10 reviews

Comfort in the Lowcountry • 3BR 1.5BA • 1GB Wi-Fi

Experience relaxed Southern comfort in this, single level 3BR/1.5BA Guest Favorite on a quiet, 1 acre lot in Furman, SC located off Hwy 601 near town hall. Recognized as a Top 5% Airbnb Guest Favorite, this home is consistently praised for its immaculate cleanliness, accuracy, and peaceful surroundings. Once the home of Lizzie Young, Furman’s first female and first African American mayor, this residence offers a meaningful connection to local history while delivering modern comfort.

The kitchen features white cabinetry and a spacious countertop, with essential appliances including a refrigerator and an oven. Natural light enters through a window near the sink, illuminating the wood-like flooring. An open doorway leads to a dining area in the background.
Home in Fairfax
4.77 out of 5 average rating, 26 reviews

Entire home close to everything in town!

Ideal for teachers, traveling nurses, contractors or a families needing a base, this single-family unit offers the perfect blend of comfort and convenience. This single-family unit is within walking distance of all Fairfax offers. *Please note* that being this close to the center of town also puts you closer to the train tracks. We do have other locations, still located in town but further away from the tracks. Message me to inquire about vacancies, if you don't see one available.

A comfortable living area is furnished with a dark leather sofa set and a round coffee table. Decorative pillows add texture, while a lamp and a television provide functionality. The hardwood floor complements the rich tones of the furniture.
Home in Estill
4.73 out of 5 average rating, 44 reviews

Cheerful 3 bedroom 2 bath residential home

Have your morning coffee on the front or back porch. Family dinner in the formal dining room or a BBQ in the back yard. This home sits on a 1 acre lot. It has hardwood floors throughout and carpet in the bedrooms. Explore nearby Beaufort, Hilton head, or Savannah Georgia which are all about 49 minutes from this location. Locals boast of hunting being one of the best in the state. Family reunions, girls or a boys trips, this beauty is clean functional cozy and ready for you!

Guest favorite
An aerial view showcases a spacious 4BR home set on 2 acres. Surrounding greenery includes trees and open lawn areas, with pathways leading to the main entrance. Adjacent structures and a gravel road are visible in the background, emphasizing the property’s serene setting.
Home in Yemassee
4.95 out of 5 average rating, 63 reviews

Lowcountry Orchard Getaway

Anderson Orchards – A Lowcountry Retreat Relax in this 4BR home on 2 acres with a bridge, oak tree, muscadine vines, pear, and pecan trees. Ideal for families or groups (sleeps 12+), it’s a peaceful retreat near top destinations: Beaufort – 40 min (historic downtown) Hilton Head – 1 hr (beaches, golf) Savannah – 1 hr (riverfront, nightlife) Charleston – 1 hr 15 min (historic charm) Parris Island – 45 min (boot camp grads) Plenty of space to relax and explore!

Top guest favorite
A softly lit Tiny House is nestled beneath a moss-draped tree, creating a serene ambiance at night. Reflections can be seen in the water nearby, enhancing the tranquil setting. The surrounding grass is lush and well-maintained, contributing to the peaceful rural environment.
Farm stay in Yemassee
4.99 out of 5 average rating, 88 reviews

“Tiny house” nestled on private farm

We are less than 1 mile off of I-95 in the Low Country of South Carolina. Our 62 acre farm is nestled in the “middle of nowhere, but close to every where”. We are located close Beaufort, Charleston and Savannah! Our Tiny House, which used to be our feed shed, offers beautiful scenery from the Red barn, Moss draped Live Oak trees, Pecan Grove, horses, goats, free range donkeys and more. We have a brand new Bathhouse with a full bath. Washer & Dryer too!

Guest favorite
A spacious wooden deck is seen, surrounded by tall trees, providing a serene outdoor space. Two red chairs and a glass table are positioned on one side, while a wooden bench offers additional seating. Natural light filters through the greenery, enhancing the tranquil setting.
Cabin in Early Branch
4.91 out of 5 average rating, 47 reviews

"Tranquil Tiny Cabin Retreat"

"Experience the tranquility of our secluded tiny cabin in Early Branch, SC. Surrounded by nature, this charming retreat offers a peaceful escape. Relax by the fire pit, fish in the private pond, and enjoy the cozy interior with small rooms, bathroom, and kitchen. Ideal for those seeking serenity and intimacy in a rustic setting. Book now for a unique getaway unlike any other."

Guest favorite
The exterior of the cottage showcases a two-story structure with light-colored wooden siding and contrasting black trim. A welcoming entryway is highlighted by a small porch and a gentle staircase leading to the cottage door. Surrounding greenery enhances the peaceful rural setting.
Farm stay in Pineland
4.94 out of 5 average rating, 16 reviews

The Cottage

15 minutes off I-95! Welcome to our charming 1-bedroom, 1-bathroom cottage nestled on a picturesque family farm! Ideal for a peaceful retreat, this cozy cottage offers a perfect blend of rustic charm and modern amenities. Located less than an hour to Beaufort, Bluffton, and Savannah. The loft bedroom is accessible only by a ladder, so please consider this when booking.

Guest favorite
A spacious bedroom features a four-poster bed topped with white and gray bedding. Two windows with light-filtering curtains provide natural light, while a dresser and a television are positioned in the room, creating a comfortable and functional space.
Home in Fairfax
5 out of 5 average rating, 17 reviews

Darlington's corner

This home is nestled in a charming neighborhood directly off of highway, 278. Making it perfect for traveling construction and healthcare professionals. Within walking distance to Fairfax\Allendale hospital only 10 miles from Hampton regional medical center. Experience the charm of the South in this Idyllic retreat.

Popular amenities for Hampton County vacation rentals