House vacation rentals in Greater Uptown

Find and book unique houses on Airbnb

Top-rated house rentals in Greater Uptown

Guests agree: these houses are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Guest favorite

Home in The Museum District

4.94 out of 5 average rating, 219 reviews

Stately 2,400-square-foot Home in Museum Park Place

2400 sq ft stately, stand alone patio home. Enjoy a private driveway, 2 living spaces, eat in kitchen, formal dining, bedrooms (conveniently located on the same floor), in house laundry, and a covetted outdoor patio space to enjoy. 2nd living room has a full body reclining massage chair, large TV and access to the outdoor space. Home was recently designed and updated with all new furniture and decor. Offering a true gallery home experience, we currently are displaying several large paintings by local artist Rylie Caldwell. Her beautiful original paintings are sure to remind you of all the fabulous art you can find throughout the city and inspire you to get out and explore! Great for families, we have a fully stocked kitchen with coffee bar and even baby gates available upon request. Everything you need for your home away from home! Enjoy the whole house and outdoor space. I live just a couple of blocks away and am available for suggestions on the area and whatever else you may need. Located in Museum Park between downtown and the Medical Center, the neighborhood offers restaurants of all kinds, while nearby Hermann Park has a great running trail. Walk to the Light Rail and travel to the Theater District to take in a show. Walkable neighborhood, close to the light rail, and bike rental stations, with quick and easy access to all the highways.

Top guest favorite

Home in Washington Avenue Coalition / Memorial Park

4.99 out of 5 average rating, 116 reviews

Location, Modern, Convenient & Safe

In the Heart of Houston! 2 minutes from Memorial Park - less than 10 minutes from the Galleria -Downtown & 12 minutes from the Med Center, just seconds from freeway with easy access points! Freshly renovated and remodeled home giving it just the right touch to make your stay as clean, crisp and luxurious as you deserve! Bike trail? Walking Trail? This home leads you straight to both within minutes… This is an experience, not just a home, equipped with everything needed to live comfortably!☺️

Guest favorite

Home in Braeswood Place

4.8 out of 5 average rating, 148 reviews

Spacious and Modern Home Near NRG & Medical Center

Welcome to the DEAL house! This newly renovated 3 bedroom, 2.5 bath home is perfectly situated in Houston. Whether its the Houston Rodeo, a Texans game, or catching a great concert, our proximity to NRG cant be beat! The home is situated in a quiet neighborhood on a tree lined street. Our home is a 1 mi walk to NRG. Its a 2 mi or 10 min drive to the Texas Medical Center and close to 15 min drive to downtown Houston. We're also a 10 min drive to the Galleria. We look forward to hosting you!

Top guest favorite

Home in Neartown - Montrose

5 out of 5 average rating, 131 reviews

RIVER OAKS 🤩 4BR 3300 sq ft ❤️CLOSE TO EVERYTHING!!

LOCATION! LOCATION! *Rated in top 5% of Homes on Airbnb* Rare find! Nestled on a quiet & safe tree lined street in the middle of the city. Walk to fine dining, shops, gym, bookstore & grocery stores. Less than 5 miles from sports stadia, Medical Center, Downtown & The Galleria! *FAST 300 mbps WIFI* 3300 sq ft of luxe living w/ a serene & tranquil atmosphere. 4BR, 3.5 baths, washer/dryer, whirlpool bathtub. Dressing room with 3 stations for hair & makeup. Private patio w/ relaxing fountain.

Top guest favorite

Home in Texas Medical Center

4.99 out of 5 average rating, 162 reviews

2BR for 1-5pp - 1/3mile Med Cen - 1/2mile Rice Uni

*2 min walk to Med Center *2 min walk to metro to downtown & NRG *5 min walk to Rice Uni area *10 min walk to Hermann Park *Suitable & spacious for 1 to 5pp *A light airy all hardwoods 2 bedroom / 2 bath private duplex renovated in 2021 *1300 sqft downstairs unit in newly furnished 1940s house *Wifi, Smart TV, W/D access, ample luxury bedding, towels & comp bath amenities & coffee galore! *Dyson Hepafilter & GermGuardian units *Full kitchen *Private entrance *1 off road parking or permit spot

Top guest favorite

Home in Greater Heights

5 out of 5 average rating, 195 reviews

All Fees included/ New Bungalow in Houston Heights

The Bungalow is centrally located in one of Houston's most up-and-coming neighborhoods, Houston Heights, which boasts a wide array of unique cafes, boutiques, and local eateries. Let your body and mind enjoy a relaxing getaway at this newly constructed house with multiple outdoor spaces. Feel like exploring all Houston has to offer? —Downtown Houston is only a five minute drive, and both the Galleria and Montrose are within 15 minutes.Enjoy a stylish experience at this centrally-located place.

Guest favorite

Home in Neartown - Montrose

4.96 out of 5 average rating, 758 reviews

Vibrant Montrose Escape: Fast WiFi, Relaxing Porch

Step into a vibrant Houston getaway with this chic duplex home, featuring a stylish monochrome interior accented w/ colorful art. Enjoy your own back porch & a BBQ gazebo in a lush backyard. Located just 5 minutes from amenities like Whole Foods & Buffalo Bayou, & nestled in the trendy Lower Montrose area, your urban retreat awaits. W/ 2 queen beds, a cozy living space, & Houston’s best attractions at your doorstep, get ready for an unforgettable stay. Book now for your perfect HTX experience!

Guest favorite

Home in Braeswood Place

4.93 out of 5 average rating, 136 reviews

Light & Airy 3B/3B near the Texas Medical Center

This is the home you have been looking for! Here you have 3 bedrooms, each with an en-suite bathroom, home that can comfortably sleep 6 people. Family and dog friendly! We are on a major bus line that will take you into the light rail station that can take you anywhere you want to go in the city! We are tucked away on a quiet street, you'd never know 3 major league stadiums are close by, the world renowned TMC is a 10 min drive, and some amazing dining options are within walking distance.

Guest favorite

Home in Northwest Houston

4.88 out of 5 average rating, 138 reviews

Serene 2-Story Full Suite - Little Tokyo

Stunning, Japanese-themed get away in Houston. Enjoy our serene 2-story space that includes a comfy queen size bed, kitchenette, dining area and sectional couch (with pull-out). Just a stone throw away is Kirby Ice House Bar, Memorial City Mall, Terry Hershey park and City Centre. Our neighborhood is lined with majestic oak trees. Enjoy the convenience of being in the city, but tucked away in your own quiet oasis. Parking, Wifi, Complimentary Tea... please be our guest. ARIGATO (Thank you!)

Guest favorite

Home in Houston

4.99 out of 5 average rating, 128 reviews

Kirby Haus · Modern Elegance for 14 · Rice Village

Kirby Haus - Our luxurious 3900 sqft modern home conveniently located in Rice Village boasts 4 spacious bedrooms with en-suite bathrooms. ***CENTRAL*** Walking distance to fine restaurants and shopping! Rodeo Houston at NRG Stadium -2 mi~5mins MD Anderson Cancer-2mi.~6mins Texas Medical Center-2mi~7mins Rice University-.08 mi.~4mins Downtown(4.7 mi.~8 mins) River Oaks-1.7mi~5mins Toyota Center-5mi~7mins Galleria-4 mi.~8 mins Minute Maid Park -5.7mi~9mins Memorial Park Golf -5mi~12mins

Guest favorite

Home in Greater Heights

4.93 out of 5 average rating, 241 reviews

Heights Craftsman Bungalow in the Trees

Built in 1922, this charmingly restored garage apartment, up in the trees, is full of natural light and original art. (Blackout curtains in bedroom.) Full kitchen: range & oven, refrigerator, washer/dryer. Living room with TV with Roku, Showtime, premium channels Dining room/office Bathroom with shower or tub (shampoo etc; high quality linens provided). WIFI (strong signal) 3 blocks from 19th Street (Heights shopping and great dining). Off street, onsite covered parking.

Guest favorite

Home in Houston

4.94 out of 5 average rating, 118 reviews

Luxurious Central Heights Home King Suite

Welcome to Woodbrook! Walk the beautiful urban green space and nature trails. Explore, bike, run, or walk the convenient Heights Hike & Bike Trails. Whether your stay is related to Business, Health, Travel, or Pleasure, you;re in the best location in Houston...mins to Downtown, Galleria, Washington, Memorial Park, Medical Center, Washington or Energy Corridors, Katy, and easy access to all major freeways 1-10,610 Loop, I-45, 59 Freeway, 288, and 290