Vacation rentals in DeSoto County

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Top-rated vacation rentals in DeSoto County

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Superhost
The lake house is nestled among lush greenery, featuring large windows that provide views of the surroundings. Warm lights illuminate the exterior, creating a welcoming ambiance. A wooden deck leads to the entrance, surrounded by trees and natural landscaping.
Home in Hernando
4.87 out of 5 average rating, 250 reviews

Hernando Hideaway (Entire Lakehouse)

Enjoy our 2000 sq ft lake house in a private peaceful community with panoramic views of the lake. We are a licensed BNB with DeSoto County and the State of Mississippi until the year 2035. (Lic # 20110070) You will have the entire lake house to yourself and we provide coffee and pastries for breakfast. We are 15 minutes from Tunica Expo, 5 minutes to Tunica National Golf Course, 10 Minutes to the casinos; 38 minutes to Beale St, Bass Pro Shop, Peabody Hotel, Graceland and The Lorraine Hotel.

Top guest favorite
Home in Southaven
5 out of 5 average rating, 27 reviews

Stylish & Cozy~5 min to Landers CTR+ Fenced Yard!

Step into this stylish and comfortable living area. The home features two spacious bedrooms and a double futon for extra guests. Located just minutes from great dining and shopping. Fully fenced yard! ☆18 min to Memphis Airport ☆12 min to Snowden Grove ☆5 min to Landers ☆17 min to Graceland ☆Fenced yard ☆USB plug in ☆Free parking ☆Dedicated workspace ☆Washer/Dryer ☆Roku TV in both bedroom ☆BBQ ☆Patio with Pergola ☆Fully stocked kitchen ☆Self check-in/digital guide book ☆5 min walk to park

Guest favorite
The exterior of the cottage is framed with natural wood and features a screened porch, allowing for views of the surrounding forest. A wooden staircase leads to the entrance, and a stone pathway guides visitors through the lush, green landscape.
Cottage in Coldwater
4.94 out of 5 average rating, 180 reviews

Wynnewood - Odell Cottage

Country get-away! Only 30 Minutes from Downtown Memphis, TN, yet out in the country on a 62 acre estate. Nature trails through the property allow for beautiful, peaceful strolls. We have fishing (in season). **** This cottage is set back in the woods and there is not a TV in this unit but there is Wifi. We have created a serene and unplugged experience. We have the "Wynnewood Elizabeth Cottage" and the "Wynnewood Jettie Jewel cottage" on our property that are listed separately.

Top guest favorite
A clear view of the detached guesthouse is showcased, featuring a covered porch with rocking chairs. The well-maintained pool reflects sunlight, with surrounding concrete patio enhancing the outdoor space. A clock and decorative elements adorn the porch, adding a welcoming touch.
Guesthouse in Hernando
4.99 out of 5 average rating, 251 reviews

Guesthouse 1 bed, beautiful views NO cleaning fees

Adorable 1 bedroom quite hide-a-way, but still have the convenience of being located close to everything. There are beautiful views from the front covered porch. NO PARTIES! Located about 20 minutes from Memphis and Tunica Casino Strip. Enjoy local attractions: Hernando Town Square, Snowden Grove, Shopping, Graceland, Memphis Botanic Gardens, Museums and Beale Street. This area and home is made for family life, not for the party style, come and enjoy your tranquil stay with us.

Guest favorite
The exterior of the home features a well-maintained facade with large windows framed by manicured greenery. A gentle rise of steps leads to the entrance, surrounded by lush lawns and mature trees under a clear blue sky.
Home in Olive Branch
4.97 out of 5 average rating, 59 reviews

Pleasant Hill Estate

Welcome to our unique and stylish home, nestled in a serene environment. With thoughtful amenities & a warm ambiance, you’ll never regret choosing to stay here. The property features elegant architectural design with natural stones, providing a harmonious blend of elegance and natural beauty. The well-maintained exterior, with a beautiful lake and inviting landscaping, adds to the overall appeal of the 8-acre land with oak and magnolia trees. Book your unforgettable experience today!

Top guest favorite
A guesthouse is nestled among green trees and lush grass, with a pathway leading to a bright red door. Two small chairs are positioned in front of the entrance, inviting guests to relax in the outdoor space.
Guesthouse in Hernando
4.99 out of 5 average rating, 138 reviews

Cozy 2 Bedroom Guesthouse in a Relaxing Setting

Our two bedroom, two bath guesthouse is the perfect get-a-way from it all, yet close enough to everything you're looking to do: 3 minutes to the historic Hernando Town Square, 10 minutes to the MS River Delta and Historic Hwy 61, 12 minutes to Tanger Outlets & Landers Center in Southaven, 20 minutes to Snowden Grove Ballfields & Amphitheatre in Southaven, 23 minutes to Tunica Casino Strip, 25 minutes to Midtown/Downtown Memphis, 1 hour to Oxford, MS and 1 hour to Clarksdale, MS.

Guest favorite
A white picket fence frames the entrance to a wooded area as the sun sets, casting shades of pink and orange across the sky. Leafless trees stand along the winding path that leads deeper into the serene surroundings.
Home in Hernando
4.92 out of 5 average rating, 144 reviews

DeerRun:Hidden Gem with Woods,Wildlife,and Gardens

Deer Run is close to Memphis,TN, I-55, restaurants and dining, great views. The spacious, 750+ sq ft cottage on 10 acres is good for retiree, couple, solo and business travelers alike. We look forward to sharing our property in this semi-secluded setting. Come relax in the comfy 12 inch deep foam mattress with super soft sheets. Enjoy the splendor of the woods, wildlife and gardens. We are far enough off the road that you will not see the street. Wheelchair accessible.

Top guest favorite
The tiny house features a rustic wooden exterior with a red metal roof. Soft ambient lights are strung around the door area, which is framed by greenery and flower beds. Outdoor seating is provided by two white chairs on a gravel patio, creating a welcoming space.
Tiny home in Olive Branch
4.98 out of 5 average rating, 152 reviews

The Pony

-Boasting a small hoofprint of 128 square feet with a loft. Ideally situated in a safe area for those visiting/passing through Memphis. -Tranquil views of open fields, horses, and a variety of other furry friends at a working horse boarding barn. -Stay solo or with someone you don't mind cozying up to. Ideal for mobile guests comfortable with stairs and tighter spaces. Locals or those without positive reviews will be rejected. Our property is non smoking.

Guest favorite
A welcoming exterior view features a brick facade complemented by lush ivy. A sign reading 'IVY' is prominently displayed within the greenery. Seating areas with wooden lounge chairs are positioned on the patio, inviting relaxation in a serene outdoor setting.
Home in Hernando
4.94 out of 5 average rating, 85 reviews

Cozy 2-Bedroom Home in downtown Hernando

Enjoy this cozy 2-bedroom 2-bathroom house in walking distance to restaurants, bars, and boutiques for shopping. This cozy home is located in the town of Hernando, Mississippi. With less than a 30 minute drive to Memphis , a 10 minute drive to Southaven, and less than an hour to Oxford, this location offers various day trip opportunities!

Guest favorite
A covered patio features rocking chairs, providing views of a sunset over a tranquil waterway. The soft light reflects on the water, blending with the expansive landscape of the Mississippi Delta, framed by natural elements and open sky.
Cottage in Lake Cormorant
4.97 out of 5 average rating, 33 reviews

Green River Place Guest House

Enjoy a historic getaway at this brand new farmhouse overlooking the beautiful Mississippi Delta. This is an experience you must see to believe. Artifacts from the Delta can be found throughout this beautiful establishment and the view from the front patio is breathtaking.

Guest favorite
A bright living area is featured with a modern white couch adorned with golden and pink decorative pillows. A glass coffee table sits at the center, complemented by a decorative area rug. The space is enhanced by a cozy fireplace and natural light streaming through the nearby window.
Home in Southaven
4.84 out of 5 average rating, 116 reviews

center of southaven home

Heart of southaven. 10-15 minutes to access everything in southaven such as food, shopping mall, outlet, hospital, airport etc. Peace and safe environment to enjoy getaway and visiting

Top guest favorite
Guesthouse in Olive Branch
5 out of 5 average rating, 85 reviews

A hidden get away

A private secluded, romantic cottage. Very contemporary and Beautiful scenery’s all around the house. Fully fenced in for pets to enjoy 🦮🐶🐾🐈🐱🐈‍⬛

Popular amenities for DeSoto County vacation rentals